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Items: 1 to 20 of 91

1.

Enhanced genotoxicity of silver nanoparticles in DNA repair deficient Mammalian cells.

Lim HK, Asharani PV, Hande MP.

Front Genet. 2012 Jun 13;3:104. doi: 10.3389/fgene.2012.00104. eCollection 2012.

2.

DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells.

Lim HK, Gurung RL, Hande MP.

Mutat Res. 2017 Dec;824:32-41. doi: 10.1016/j.mrgentox.2017.10.001. Epub 2017 Oct 13.

PMID:
29150048
3.

Biochemical evidence for Ku-independent backup pathways of NHEJ.

Wang H, Perrault AR, Takeda Y, Qin W, Wang H, Iliakis G.

Nucleic Acids Res. 2003 Sep 15;31(18):5377-88.

5.

Non-homologous end joining is the responsible pathway for the repair of fludarabine-induced DNA double strand breaks in mammalian cells.

de Campos-Nebel M, Larripa I, González-Cid M.

Mutat Res. 2008 Nov 10;646(1-2):8-16. doi: 10.1016/j.mrfmmm.2008.08.013. Epub 2008 Sep 4.

PMID:
18812179
6.

Wortmannin potentiates the combined effect of etoposide and cisplatin in human glioma cells.

Pastwa E, Poplawski T, Lewandowska U, Somiari SB, Blasiak J, Somiari RI.

Int J Biochem Cell Biol. 2014 Aug;53:423-31. doi: 10.1016/j.biocel.2014.06.007. Epub 2014 Jun 19.

PMID:
24953561
7.

Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.

Wang H, Zeng ZC, Perrault AR, Cheng X, Qin W, Iliakis G.

Nucleic Acids Res. 2001 Apr 15;29(8):1653-60.

8.

Akt promotes post-irradiation survival of human tumor cells through initiation, progression, and termination of DNA-PKcs-dependent DNA double-strand break repair.

Toulany M, Lee KJ, Fattah KR, Lin YF, Fehrenbacher B, Schaller M, Chen BP, Chen DJ, Rodemann HP.

Mol Cancer Res. 2012 Jul;10(7):945-57. doi: 10.1158/1541-7786.MCR-11-0592. Epub 2012 May 17.

9.

Inhibition of homologous recombination by variants of the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs).

Convery E, Shin EK, Ding Q, Wang W, Douglas P, Davis LS, Nickoloff JA, Lees-Miller SP, Meek K.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1345-50. Epub 2005 Jan 24.

10.

DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption.

Zhou X, Zhang X, Xie Y, Tanaka K, Wang B, Zhang H.

PLoS One. 2013 Aug 27;8(8):e72641. doi: 10.1371/journal.pone.0072641. eCollection 2013.

11.
12.

Cytotoxicity and genotoxicity of silver nanoparticles in human cells.

AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S.

ACS Nano. 2009 Feb 24;3(2):279-90. doi: 10.1021/nn800596w.

PMID:
19236062
13.

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage.

Olsen BB, Wang SY, Svenstrup TH, Chen BP, Guerra B.

BMC Mol Biol. 2012 Mar 9;13:7. doi: 10.1186/1471-2199-13-7.

14.

Heat exposure enhances radiosensitivity by depressing DNA-PK kinase activity during double strand break repair.

Ihara M, Takeshita S, Okaichi K, Okumura Y, Ohnishi T.

Int J Hyperthermia. 2014 Mar;30(2):102-9. doi: 10.3109/02656736.2014.887793.

PMID:
24571173
15.

Inhibition of ERK activation enhances the repair of double-stranded breaks via non-homologous end joining by increasing DNA-PKcs activation.

Wei F, Yan J, Tang D, Lin X, He L, Xie Y, Tao L, Wang S.

Biochim Biophys Acta. 2013 Jan;1833(1):90-100. doi: 10.1016/j.bbamcr.2012.10.016. Epub 2012 Oct 23.

16.

Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair.

Gustafsson AS, Abramenkovs A, Stenerlöw B.

Mutat Res. 2014 Nov;769:1-10. doi: 10.1016/j.mrfmmm.2014.06.004. Epub 2014 Jun 22.

17.

Autophosphorylation-dependent remodeling of the DNA-dependent protein kinase catalytic subunit regulates ligation of DNA ends.

Block WD, Yu Y, Merkle D, Gifford JL, Ding Q, Meek K, Lees-Miller SP.

Nucleic Acids Res. 2004 Aug 16;32(14):4351-7. Print 2004.

18.

Mechanisms of DNA double strand break repair and chromosome aberration formation.

Iliakis G, Wang H, Perrault AR, Boecker W, Rosidi B, Windhofer F, Wu W, Guan J, Terzoudi G, Pantelias G.

Cytogenet Genome Res. 2004;104(1-4):14-20. Review.

PMID:
15162010
19.

The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damage.

Reynolds P, Anderson JA, Harper JV, Hill MA, Botchway SW, Parker AW, O'Neill P.

Nucleic Acids Res. 2012 Nov;40(21):10821-31. doi: 10.1093/nar/gks879. Epub 2012 Sep 24.

20.

Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.

Boldogh I, Roy G, Lee MS, Bacsi A, Hazra TK, Bhakat KK, Das GC, Mitra S.

Toxicology. 2003 Nov 15;193(1-2):137-52.

PMID:
14599773

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