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Use of class I and class II HLA loci for predicting age at onset of type 1 diabetes in multiple populations.

Valdes AM, Erlich HA, Carlson J, Varney M, Moonsamy PV, Noble JA.

Diabetologia. 2012 Sep;55(9):2394-401. doi: 10.1007/s00125-012-2608-z. Epub 2012 Jun 17.


The association of specific HLA class I and II alleles with type 1 diabetes among Filipinos.

Bugawan TL, Klitz W, Alejandrino M, Ching J, Panelo A, Solfelix CM, Petrone A, Buzzetti R, Pozzilli P, Erlich HA.

Tissue Antigens. 2002 Jun;59(6):452-69.


HLA class I and genetic susceptibility to type 1 diabetes: results from the Type 1 Diabetes Genetics Consortium.

Noble JA, Valdes AM, Varney MD, Carlson JA, Moonsamy P, Fear AL, Lane JA, Lavant E, Rappner R, Louey A, Concannon P, Mychaleckyj JC, Erlich HA; Type 1 Diabetes Genetics Consortium.

Diabetes. 2010 Nov;59(11):2972-9. doi: 10.2337/db10-0699. Epub 2010 Aug 26.


The distribution of HLA class II susceptible/protective haplotypes could partially explain the low incidence of type 1 diabetes in continental Italy (Lazio region).

Petrone A, Bugawan TL, Mesturino CA, Nisticò L, Galgani A, Giorgi G, Cascino I, Erlich HA, Di Mario U, Buzzetti R.

Tissue Antigens. 2001 Dec;58(6):385-94.


14th International HLA and Immunogenetics Workshop: report on the HLA component of type 1 diabetes.

Steenkiste A, Valdes AM, Feolo M, Hoffman D, Concannon P, Noble J, Schoch G, Hansen J, Helmberg W, Dorman JS, Thomson G, Pugliese A; 13th IHWS 1 Diabetes Component participating investigators.

Tissue Antigens. 2007 Apr;69 Suppl 1:214-25. Review.


Absolute risk of childhood-onset type 1 diabetes defined by human leukocyte antigen class II genotype: a population-based study in the United Kingdom.

Lambert AP, Gillespie KM, Thomson G, Cordell HJ, Todd JA, Gale EA, Bingley PJ.

J Clin Endocrinol Metab. 2004 Aug;89(8):4037-43.


Stepwise or linear decrease in penetrance of type 1 diabetes with lower-risk HLA genotypes over the past 40 years.

Steck AK, Armstrong TK, Babu SR, Eisenbarth GS; Type 1 Diabetes Genetics Consortium.

Diabetes. 2011 Mar;60(3):1045-9. doi: 10.2337/db10-1419. Epub 2011 Feb 9.


HLA class I (A, B, C) and class II (DRB1, DQA1, DQB1, DPB1) alleles and haplotypes in the Han from southern China.

Trachtenberg E, Vinson M, Hayes E, Hsu YM, Houtchens K, Erlich H, Klitz W, Hsia Y, Hollenbach J.

Tissue Antigens. 2007 Dec;70(6):455-63. Epub 2007 Sep 27.


Two distinct MICA gene markers discriminate major autoimmune diabetes types.

Gambelunghe G, Ghaderi M, Tortoioli C, Falorni A, Santeusanio F, Brunetti P, Sanjeevi CB, Falorni A; Umbria Type 1 Diabetes Registry.

J Clin Endocrinol Metab. 2001 Aug;86(8):3754-60.


Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) Group.

Horton V, Stratton I, Bottazzo GF, Shattock M, Mackay I, Zimmet P, Manley S, Holman R, Turner R.

Diabetologia. 1999 May;42(5):608-16.


Genetics of the HLA region in the prediction of type 1 diabetes.

Noble JA, Valdes AM.

Curr Diab Rep. 2011 Dec;11(6):533-42. doi: 10.1007/s11892-011-0223-x. Review.


Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes.

Lipponen K, Gombos Z, Kiviniemi M, Siljander H, Lempainen J, Hermann R, Veijola R, Simell O, Knip M, Ilonen J.

Diabetes. 2010 Dec;59(12):3253-6. doi: 10.2337/db10-0167. Epub 2010 Aug 25.


Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin-dependent) diabetes mellitus.

Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Ono M, Nishino M, Taniguchi H, Noso S, Yamada K, Babaya N, Ogihara T.

Hum Immunol. 2000 Jun;61(6):624-9.


Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies.

James I, McKinnon E, Gaudieri S, Morahan G; Diabetes Genetics Consortium.

Diabetes Obes Metab. 2009 Feb;11 Suppl 1:101-7. doi: 10.1111/j.1463-1326.2008.01010.x.


HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families.

Erlich H, Valdes AM, Noble J, Carlson JA, Varney M, Concannon P, Mychaleckyj JC, Todd JA, Bonella P, Fear AL, Lavant E, Louey A, Moonsamy P; Type 1 Diabetes Genetics Consortium.

Diabetes. 2008 Apr;57(4):1084-92. doi: 10.2337/db07-1331. Epub 2008 Feb 5.


A second component of HLA-linked susceptibility to type 1 diabetes maps to class I region.

Kawabata Y, Ikegami H, Fujisawa T, Noso S, Asano K, Hiromine Y, Ogihara T.

Ann N Y Acad Sci. 2006 Oct;1079:278-84.


[Predictive genetic screening for type-1 diabetes in the Hungarian population].

Hermann R, Soltész G.

Orv Hetil. 2004 Feb 15;145(7):337-42. Hungarian.


Analysis of the HLA and non-HLA susceptibility loci in Japanese type 1 diabetes.

Yamashita H, Awata T, Kawasaki E, Ikegami H, Tanaka S, Maruyama T, Shimada A, Nakanishi K, Takahashi K, Kobayashi T, Kawabata Y, Miyashita Y, Kurihara S, Morita-Ohkubo T, Katayama S; Japanese Study Group on Type 1 Diabetes Genetics.

Diabetes Metab Res Rev. 2011 Nov;27(8):844-8. doi: 10.1002/dmrr.1234.


Low frequency of HLA DRB1*03 - DQB1*02 and DQB1*0302 haplotypes in Romania is consistent with the country's low incidence of Type I diabetes.

Ionescu-Tîrgoviste C, Guja C, Herr M, Cucca E, Welsh K, Bunce M, Marshall S, Todd JA.

Diabetologia. 2001 Oct;44 Suppl 3:B60-6.


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