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Items: 1 to 20 of 160

1.

Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells.

Motterle A, Pu X, Wood H, Xiao Q, Gor S, Ng FL, Chan K, Cross F, Shohreh B, Poston RN, Tucker AT, Caulfield MJ, Ye S.

Hum Mol Genet. 2012 Sep 15;21(18):4021-9. doi: 10.1093/hmg/dds224. Epub 2012 Jun 15.

2.

Expression of Chr9p21 genes CDKN2B (p15(INK4b)), CDKN2A (p16(INK4a), p14(ARF)) and MTAP in human atherosclerotic plaque.

Holdt LM, Sass K, Gäbel G, Bergert H, Thiery J, Teupser D.

Atherosclerosis. 2011 Feb;214(2):264-70. doi: 10.1016/j.atherosclerosis.2010.06.029. Epub 2010 Jun 23.

PMID:
20637465
3.

Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B.

Congrains A, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T, Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi M, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H.

Atherosclerosis. 2012 Feb;220(2):449-55. doi: 10.1016/j.atherosclerosis.2011.11.017. Epub 2011 Nov 19.

PMID:
22178423
4.

Methylation of p15INK4b and expression of ANRIL on chromosome 9p21 are associated with coronary artery disease.

Zhuang J, Peng W, Li H, Wang W, Wei Y, Li W, Xu Y.

PLoS One. 2012;7(10):e47193. doi: 10.1371/journal.pone.0047193. Epub 2012 Oct 16.

5.

Interferon-γ activates expression of p15 and p16 regardless of 9p21.3 coronary artery disease risk genotype.

Almontashiri NA, Fan M, Cheng BL, Chen HH, Roberts R, Stewart AF.

J Am Coll Cardiol. 2013 Jan 15;61(2):143-7. doi: 10.1016/j.jacc.2012.08.1020. Epub 2012 Nov 28.

6.

Resequencing and clinical associations of the 9p21.3 region: a comprehensive investigation in the Framingham heart study.

Johnson AD, Hwang SJ, Voorman A, Morrison A, Peloso GM, Hsu YH, Thanassoulis G, Newton-Cheh C, Rogers IS, Hoffmann U, Freedman JE, Fox CS, Psaty BM, Boerwinkle E, Cupples LA, O'Donnell CJ.

Circulation. 2013 Feb 19;127(7):799-810. doi: 10.1161/CIRCULATIONAHA.112.111559. Epub 2013 Jan 11.

7.

Expression of linear and novel circular forms of an INK4/ARF-associated non-coding RNA correlates with atherosclerosis risk.

Burd CE, Jeck WR, Liu Y, Sanoff HK, Wang Z, Sharpless NE.

PLoS Genet. 2010 Dec 2;6(12):e1001233. doi: 10.1371/journal.pgen.1001233.

8.

Fine-mapping loss of gene architecture at the CDKN2B (p15INK4b), CDKN2A (p14ARF, p16INK4a), and MTAP genes in head and neck squamous cell carcinoma.

Worsham MJ, Chen KM, Tiwari N, Pals G, Schouten JP, Sethi S, Benninger MS.

Arch Otolaryngol Head Neck Surg. 2006 Apr;132(4):409-15.

PMID:
16618910
9.

[Methylation profile of INK4B-ARF-INK4A locus in atherosclerosis].

Nazarenko MS, Markov AV, Lebedev IN, Slepsov AA, Koroleva YA, Frolov AV, Barbarash OL, Barbarash LS, Puzirev VP.

Genetika. 2013 Jun;49(6):783-7. Russian.

PMID:
24450202
10.

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.

Visel A, Zhu Y, May D, Afzal V, Gong E, Attanasio C, Blow MJ, Cohen JC, Rubin EM, Pennacchio LA.

Nature. 2010 Mar 18;464(7287):409-12. doi: 10.1038/nature08801. Epub 2010 Feb 21.

11.

Prognostic significance of p14ARF, p15INK4b, and p16INK4a inactivation in malignant peripheral nerve sheath tumors.

Endo M, Kobayashi C, Setsu N, Takahashi Y, Kohashi K, Yamamoto H, Tamiya S, Matsuda S, Iwamoto Y, Tsuneyoshi M, Oda Y.

Clin Cancer Res. 2011 Jun 1;17(11):3771-82. doi: 10.1158/1078-0432.CCR-10-2393. Epub 2011 Jan 24.

12.

ANRIL expression is associated with atherosclerosis risk at chromosome 9p21.

Holdt LM, Beutner F, Scholz M, Gielen S, Gäbel G, Bergert H, Schuler G, Thiery J, Teupser D.

Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):620-7. doi: 10.1161/ATVBAHA.109.196832. Epub 2010 Jan 7.

13.

The severity of internal carotid artery stenosis is associated with the cyclin-dependent kinase inhibitor 2A gene expression.

Bayoglu B, Arslan C, Gode S, Kaya Dagistanli F, Arapi B, Burc Deser S, Dirican A, Cengiz M.

J Atheroscler Thromb. 2014;21(7):659-71. Epub 2014 Mar 5.

14.

Genetic mechanisms mediating atherosclerosis susceptibility at the chromosome 9p21 locus.

Cunnington MS, Keavney B.

Curr Atheroscler Rep. 2011 Jun;13(3):193-201. doi: 10.1007/s11883-011-0178-z. Review.

PMID:
21487702
15.

Functional genomics of the 9p21.3 locus for atherosclerosis: clarity or confusion?

Chen HH, Almontashiri NA, Antoine D, Stewart AF.

Curr Cardiol Rep. 2014 Jul;16(7):502. doi: 10.1007/s11886-014-0502-7. Review.

PMID:
24893939
16.

9p21.3 Coronary Artery Disease Risk Variants Disrupt TEAD Transcription Factor-Dependent Transforming Growth Factor β Regulation of p16 Expression in Human Aortic Smooth Muscle Cells.

Almontashiri NA, Antoine D, Zhou X, Vilmundarson RO, Zhang SX, Hao KN, Chen HH, Stewart AF.

Circulation. 2015 Nov 24;132(21):1969-78. doi: 10.1161/CIRCULATIONAHA.114.015023. Epub 2015 Oct 20.

17.

Role of noncoding RNA ANRIL in genesis of plexiform neurofibromas in neurofibromatosis type 1.

Pasmant E, Sabbagh A, Masliah-Planchon J, Ortonne N, Laurendeau I, Melin L, Ferkal S, Hernandez L, Leroy K, Valeyrie-Allanore L, Parfait B, Vidaud D, Bièche I, Lantieri L, Wolkenstein P, Vidaud M; NF France Network.

J Natl Cancer Inst. 2011 Nov 16;103(22):1713-22. doi: 10.1093/jnci/djr416. Epub 2011 Oct 27.

PMID:
22034633
18.

Genomic instability, mutations and expression analysis of the tumour suppressor genes p14(ARF), p15(INK4b), p16(INK4a) and p53 in actinic keratosis.

Kanellou P, Zaravinos A, Zioga M, Stratigos A, Baritaki S, Soufla G, Zoras O, Spandidos DA.

Cancer Lett. 2008 Jun 8;264(1):145-61. doi: 10.1016/j.canlet.2008.01.042. Epub 2008 Mar 10.

PMID:
18331779
19.

Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene.

Kotake Y, Nakagawa T, Kitagawa K, Suzuki S, Liu N, Kitagawa M, Xiong Y.

Oncogene. 2011 Apr 21;30(16):1956-62. doi: 10.1038/onc.2010.568. Epub 2010 Dec 13.

20.

Ocular expression and distribution of products of the POAG-associated chromosome 9p21 gene region.

Chidlow G, Wood JP, Sharma S, Dimasi DP, Burdon KP, Casson RJ, Craig JE.

PLoS One. 2013 Sep 19;8(9):e75067. doi: 10.1371/journal.pone.0075067. eCollection 2013.

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