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Items: 1 to 20 of 120

1.

Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model.

Kim PH, Lee M, Kim SW.

J Control Release. 2012 Aug 20;162(1):9-18. doi: 10.1016/j.jconrel.2012.06.010. Epub 2012 Jun 15.

2.

Efficient GLP-1 gene delivery using two-step transcription amplification plasmid system with a secretion signal peptide and arginine-grafted bioreducible polymer.

Kim TI, Lee M, Kim SW.

J Control Release. 2012 Jan 30;157(2):243-8. doi: 10.1016/j.jconrel.2011.09.072. Epub 2011 Sep 16.

4.

An efficient GLP-1 expression system using two-step transcription amplification.

Lee M, Oh S, Ahn CH, Kim SW, Rhee BD, Ko KS; Mitochondrial Research Group.

J Control Release. 2006 Oct 27;115(3):316-21. Epub 2006 Jul 21.

PMID:
17045357
5.

A new orally available glucagon-like peptide-1 receptor agonist, biotinylated exendin-4, displays improved hypoglycemic effects in db/db mice.

Jin CH, Chae SY, Son S, Kim TH, Um KA, Youn YS, Lee S, Lee KC.

J Control Release. 2009 Feb 10;133(3):172-7. doi: 10.1016/j.jconrel.2008.09.091. Epub 2008 Oct 21.

PMID:
18977255
6.

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice.

Maida A, Hansotia T, Longuet C, Seino Y, Drucker DJ.

Gastroenterology. 2009 Dec;137(6):2146-57. doi: 10.1053/j.gastro.2009.09.004. Epub 2009 Sep 17.

PMID:
19766644
7.

A novel exendin-4 human serum albumin fusion protein, E2HSA, with an extended half-life and good glucoregulatory effect in healthy rhesus monkeys.

Zhang L, Wang L, Meng Z, Gan H, Gu R, Wu Z, Gao L, Zhu X, Sun W, Li J, Zheng Y, Dou G.

Biochem Biophys Res Commun. 2014 Mar 7;445(2):511-6. doi: 10.1016/j.bbrc.2014.02.045. Epub 2014 Feb 21.

PMID:
24565847
8.

Enhanced protection of Ins-1 beta cells from apoptosis under hypoxia by delivery of DNA encoding secretion signal peptide-linked exendin-4.

Ah Kim H, Lee S, Park JH, Lee S, Lee BW, Ihm SH, Kim TI, Kim SW, Ko KS, Lee M.

J Drug Target. 2009 Apr;17(3):242-8. doi: 10.1080/10611860902718664.

PMID:
19558363
9.

Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db Mice.

Hou S, Li C, Huan Y, Liu S, Liu Q, Sun S, Jiang Q, Jia C, Shen Z.

J Diabetes Res. 2015;2015:817839. doi: 10.1155/2015/817839. Epub 2015 Aug 17.

10.

Incretins and other peptides in the treatment of diabetes.

Todd JF, Bloom SR.

Diabet Med. 2007 Mar;24(3):223-32. Review.

PMID:
17263764
11.

Glucagon-like peptide-1 plasmid construction and delivery for the treatment of type 2 diabetes.

Choi S, Oh S, Lee M, Kim SW.

Mol Ther. 2005 Nov;12(5):885-91. Epub 2005 Jul 21.

13.

Biological activity of AC3174, a peptide analog of exendin-4.

Hargrove DM, Kendall ES, Reynolds JM, Lwin AN, Herich JP, Smith PA, Gedulin BR, Flanagan SD, Jodka CM, Hoyt JA, McCowen KM, Parkes DG, Anderson CM.

Regul Pept. 2007 Jun 7;141(1-3):113-9. Epub 2007 Jan 11.

PMID:
17292977
14.

Effects of 1-mo bolus subcutaneous administration of exendin-4 in type 2 diabetes.

Egan JM, Meneilly GS, Elahi D.

Am J Physiol Endocrinol Metab. 2003 Jun;284(6):E1072-9. Epub 2002 Dec 10.

15.

Anti-diabetic actions of glucagon-like peptide-1 on pancreatic beta-cells.

Lee YS, Jun HS.

Metabolism. 2014 Jan;63(1):9-19. doi: 10.1016/j.metabol.2013.09.010. Epub 2013 Oct 17. Review.

PMID:
24140094
16.

Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors.

Neumiller JJ.

J Am Pharm Assoc (2003). 2009 Sep-Oct;49 Suppl 1:S16-29. doi: 10.1331/JAPhA.2009.09078. Review.

PMID:
19801361
17.

Glucagon-like peptide-1 and islet lipolysis.

Sörhede Winzell M, Ahrén B.

Horm Metab Res. 2004 Nov-Dec;36(11-12):795-803.

PMID:
15655711
18.

Glucagon-like peptide 1 based therapy for type 2 diabetes.

Yu BS, Wang AR.

World J Pediatr. 2008 Feb;4(1):8-13. doi: 10.1007/s12519-008-0002-1. Review.

PMID:
18402245
19.
20.

Role of the incretin pathway in the pathogenesis of type 2 diabetes mellitus.

Freeman JS.

Cleve Clin J Med. 2009 Dec;76 Suppl 5:S12-9. doi: 10.3949/ccjm.76.s5.03. Review.

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