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Items: 1 to 20 of 137

1.

Synthesis of 6-substituted 9-methoxy-11H-indeno[1,2-c]quinoline-11-one derivatives as potential anticancer agents.

Tseng CH, Chen YL, Yang CL, Cheng CM, Han CH, Tzeng CC.

Bioorg Med Chem. 2012 Jul 15;20(14):4397-404. doi: 10.1016/j.bmc.2012.05.035. Epub 2012 Jun 1.

PMID:
22705019
2.

Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinoline derivatives.

Tseng CH, Chen YL, Chung KY, Cheng CM, Wang CH, Tzeng CC.

Bioorg Med Chem. 2009 Nov 1;17(21):7465-76. doi: 10.1016/j.bmc.2009.09.021. Epub 2009 Sep 16.

PMID:
19796956
3.

Synthesis and antiproliferative evaluation of 6-aryl-11-iminoindeno[1,2-c]quinoline derivatives.

Tseng CH, Tzeng CC, Chung KY, Kao CL, Hsu CY, Cheng CM, Huang KS, Chen YL.

Bioorg Med Chem. 2011 Dec 15;19(24):7653-63. doi: 10.1016/j.bmc.2011.10.014. Epub 2011 Oct 20.

PMID:
22079254
4.

Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2.

Tseng CH, Tzeng CC, Yang CL, Lu PJ, Chen HL, Li HY, Chuang YC, Yang CN, Chen YL.

J Med Chem. 2010 Aug 26;53(16):6164-79. doi: 10.1021/jm1005447.

PMID:
20662543
5.

Design and synthesis of 6,7-methylenedioxy-4-substituted phenylquinolin-2(1H)-one derivatives as novel anticancer agents that induce apoptosis with cell cycle arrest at G2/M phase.

Chen YF, Lin YC, Huang PK, Chan HC, Kuo SC, Lee KH, Huang LJ.

Bioorg Med Chem. 2013 Sep 1;21(17):5064-75. doi: 10.1016/j.bmc.2013.06.046. Epub 2013 Jun 26.

6.

TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells.

Liu YP, Chen HL, Tzeng CC, Lu PJ, Lo CW, Lee YC, Tseng CH, Chen YL, Yang CN.

Breast Cancer Res Treat. 2013 Apr;138(2):383-93. doi: 10.1007/s10549-013-2441-1. Epub 2013 Feb 22.

PMID:
23430225
7.

Discovery of indeno[1,2-b]quinoxaline derivatives as potential anticancer agents.

Tseng CH, Chen YR, Tzeng CC, Liu W, Chou CK, Chiu CC, Chen YL.

Eur J Med Chem. 2016 Jan 27;108:258-273. doi: 10.1016/j.ejmech.2015.11.031. Epub 2015 Nov 24.

PMID:
26686931
8.

Cytotoxicity and cell death mechanisms induced by a novel bisnaphthalimidopropyl derivative against the NCI-H460 non-small lung cancer cell line.

Lima RT, Barron GA, Grabowska JA, Bermano G, Kaur S, Roy N, Vasconcelos MH, Lin PK.

Anticancer Agents Med Chem. 2013 Mar;13(3):414-21.

PMID:
23092269
9.

Synthesis and antiproliferative evaluation of certain indolo[3,2-c]quinoline derivatives.

Lu CM, Chen YL, Chen HL, Chen CA, Lu PJ, Yang CN, Tzeng CC.

Bioorg Med Chem. 2010 Mar 1;18(5):1948-57. doi: 10.1016/j.bmc.2010.01.033. Epub 2010 Jan 28.

PMID:
20171108
10.

Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives.

Tseng CH, Chen YL, Lu PJ, Yang CN, Tzeng CC.

Bioorg Med Chem. 2008 Mar 15;16(6):3153-62. doi: 10.1016/j.bmc.2007.12.028. Epub 2007 Dec 23.

PMID:
18180162
11.

Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.

Huang WT, Liu J, Liu JF, Hui L, Ding YL, Chen SW.

Eur J Med Chem. 2012 Mar;49:48-54. doi: 10.1016/j.ejmech.2011.12.005. Epub 2011 Dec 9.

PMID:
22244588
12.

Discovery of 3-phenylquinolinylchalcone derivatives as potent and selective anticancer agents against breast cancers.

Tseng CH, Tzeng CC, Hsu CY, Cheng CM, Yang CN, Chen YL.

Eur J Med Chem. 2015 Jun 5;97:306-19. doi: 10.1016/j.ejmech.2015.04.054. Epub 2015 Apr 30.

PMID:
26005780
13.

GL-V9, a newly synthetic flavonoid derivative, induces mitochondrial-mediated apoptosis and G2/M cell cycle arrest in human hepatocellular carcinoma HepG2 cells.

Li L, Lu N, Dai Q, Wei L, Zhao Q, Li Z, He Q, Dai Y, Guo Q.

Eur J Pharmacol. 2011 Nov 16;670(1):13-21. doi: 10.1016/j.ejphar.2011.08.054. Epub 2011 Sep 17.

PMID:
21944925
14.

Induction of tumor cell death through targeting tubulin and evoking dysregulation of cell cycle regulatory proteins by multifunctional cinnamaldehydes.

Nagle AA, Gan FF, Jones G, So CL, Wells G, Chew EH.

PLoS One. 2012;7(11):e50125. doi: 10.1371/journal.pone.0050125. Epub 2012 Nov 21.

15.

Synthesis and anticancer activity of heteroaromatic linked 4β-amido podophyllotoxins as apoptotic inducing agents.

Kamal A, Tamboli JR, Vishnuvardhan MV, Adil SF, Nayak VL, Ramakrishna S.

Bioorg Med Chem Lett. 2013 Jan 1;23(1):273-80. doi: 10.1016/j.bmcl.2012.10.099. Epub 2012 Nov 1.

PMID:
23182091
16.

Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives.

Ryckebusch A, Garcin D, Lansiaux A, Goossens JF, Baldeyrou B, Houssin R, Bailly C, Hénichart JP.

J Med Chem. 2008 Jun 26;51(12):3617-29. doi: 10.1021/jm800017u. Epub 2008 May 29.

PMID:
18507368
17.

Synthesis and in vitro antiproliferative evaluation of pyrimido[5,4-c]quinoline-4-(3H)-one derivatives.

Ai Y, Liang YJ, Liu JC, He HW, Chen Y, Tang C, Yang GZ, Fu LW.

Eur J Med Chem. 2012 Jan;47(1):206-13. doi: 10.1016/j.ejmech.2011.10.044. Epub 2011 Oct 25.

PMID:
22079378
18.

Synthesis of pyrazolo[1,5-a]pyrimidine linked aminobenzothiazole conjugates as potential anticancer agents.

Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.

Bioorg Med Chem Lett. 2013 Jun 1;23(11):3208-15. doi: 10.1016/j.bmcl.2013.03.129. Epub 2013 Apr 6.

PMID:
23623491
19.

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.

J Agric Food Chem. 2012 Jan 18;60(2):665-75. doi: 10.1021/jf204193v. Epub 2012 Jan 6.

PMID:
22148415
20.

Anticancer potential of 3-(arylideneamino)-2-phenylquinazoline-4(3H)-one derivatives.

Das S, Chatterjee N, Bose D, Dey SK, Munda RN, Nandy A, Bera S, Biswas SK, Das Saha K.

Cell Physiol Biochem. 2012;29(1-2):251-60. doi: 10.1159/000337606. Epub 2012 Mar 1.

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