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Toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection.

Walsh KB, Teijaro JR, Zuniga EI, Welch MJ, Fremgen DM, Blackburn SD, von Tiehl KF, Wherry EJ, Flavell RA, Oldstone MB.

Cell Host Microbe. 2012 Jun 14;11(6):643-53. doi: 10.1016/j.chom.2012.04.016.


MyD88 is critical for the development of innate and adaptive immunity during acute lymphocytic choriomeningitis virus infection.

Zhou S, Kurt-Jones EA, Mandell L, Cerny A, Chan M, Golenbock DT, Finberg RW.

Eur J Immunol. 2005 Mar;35(3):822-30.


B Cell-intrinsic TLR7 signaling is required for optimal B cell responses during chronic viral infection.

Clingan JM, Matloubian M.

J Immunol. 2013 Jul 15;191(2):810-8. doi: 10.4049/jimmunol.1300244. Epub 2013 Jun 12.


Plasmacytoid dendritic cells control T-cell response to chronic viral infection.

Cervantes-Barragan L, Lewis KL, Firner S, Thiel V, Hugues S, Reith W, Ludewig B, Reizis B.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3012-7. doi: 10.1073/pnas.1117359109. Epub 2012 Feb 6.


Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection.

Oxenius A, Bachmann MF, Zinkernagel RM, Hengartner H.

Eur J Immunol. 1998 Jan;28(1):390-400.


Aplastic anemia rescued by exhaustion of cytokine-secreting CD8+ T cells in persistent infection with lymphocytic choriomeningitis virus.

Binder D, van den Broek MF, Kägi D, Bluethmann H, Fehr J, Hengartner H, Zinkernagel RM.

J Exp Med. 1998 Jun 1;187(11):1903-20.


Role of virus and host variables in virus persistence or immunopathological disease caused by a non-cytolytic virus.

Moskophidis D, Battegay M, van den Broek M, Laine E, Hoffmann-Rohrer U, Zinkernagel RM.

J Gen Virol. 1995 Feb;76 ( Pt 2):381-91.


Hematopoietic and nonhematopoietic cells promote Type I interferon- and TLR7-dependent monocytosis during low-dose LCMV infection.

Buechler MB, Gessay GM, Srivastava S, Campbell DJ, Hamerman JA.

Eur J Immunol. 2015 Nov;45(11):3064-72. doi: 10.1002/eji.201445331. Epub 2015 Sep 14.


The alternative NF-kappaB signalling pathway is a prerequisite for an appropriate immune response against lymphocytic choriomeningitis virus infection.

Droebner K, Klein B, Paxian S, Schmid R, Stitz L, Planz O.

Viral Immunol. 2010 Jun;23(3):295-308. doi: 10.1089/vim.2009.0101.


Nucleoprotein-specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcγR.

Straub T, Schweier O, Bruns M, Nimmerjahn F, Waisman A, Pircher H.

Eur J Immunol. 2013 Sep;43(9):2338-48. doi: 10.1002/eji.201343565. Epub 2013 Jul 15.


Negative regulation of type I IFN expression by OASL1 permits chronic viral infection and CD8⁺ T-cell exhaustion.

Lee MS, Park CH, Jeong YH, Kim YJ, Ha SJ.

PLoS Pathog. 2013;9(7):e1003478. doi: 10.1371/journal.ppat.1003478. Epub 2013 Jul 18.


Interferon regulatory factor 7 (IRF7) is required for the optimal initial control but not subsequent clearance of lymphocytic choriomeningitis virus infection in mice.

Li W, Hofer MJ, Noçon AL, Manders P, Campbell IL.

Virology. 2013 May 10;439(2):152-62. doi: 10.1016/j.virol.2013.02.015. Epub 2013 Mar 12.


Plasmacytoid dendritic cells promote host defense against acute pneumovirus infection via the TLR7-MyD88-dependent signaling pathway.

Davidson S, Kaiko G, Loh Z, Lalwani A, Zhang V, Spann K, Foo SY, Hansbro N, Uematsu S, Akira S, Matthaei KI, Rosenberg HF, Foster PS, Phipps S.

J Immunol. 2011 May 15;186(10):5938-48. doi: 10.4049/jimmunol.1002635. Epub 2011 Apr 11.


Immunosuppression by lymphocytic choriomeningitis virus infection: competent effector T and B cells but impaired antigen presentation.

Althage A, Odermatt B, Moskophidis D, Kündig T, Hoffman-Rohrer U, Hengartner H, Zinkernagel RM.

Eur J Immunol. 1992 Jul;22(7):1803-12.


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