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Items: 1 to 20 of 99

1.

Structural and biochemical consequences of disease-causing mutations in the ankyrin repeat domain of the human TRPV4 channel.

Inada H, Procko E, Sotomayor M, Gaudet R.

Biochemistry. 2012 Aug 7;51(31):6195-206. Epub 2012 Jul 25.

2.

Structural analyses of the ankyrin repeat domain of TRPV6 and related TRPV ion channels.

Phelps CB, Huang RJ, Lishko PV, Wang RR, Gaudet R.

Biochemistry. 2008 Feb 26;47(8):2476-84. doi: 10.1021/bi702109w. Epub 2008 Jan 31.

3.

TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P₂.

Takahashi N, Hamada-Nakahara S, Itoh Y, Takemura K, Shimada A, Ueda Y, Kitamata M, Matsuoka R, Hanawa-Suetsugu K, Senju Y, Mori MX, Kiyonaka S, Kohda D, Kitao A, Mori Y, Suetsugu S.

Nat Commun. 2014 Sep 26;5:4994. doi: 10.1038/ncomms5994.

PMID:
25256292
4.

Crystal structure of the N-terminal ankyrin repeat domain of TRPV3 reveals unique conformation of finger 3 loop critical for channel function.

Shi DJ, Ye S, Cao X, Zhang R, Wang K.

Protein Cell. 2013 Dec;4(12):942-50. doi: 10.1007/s13238-013-3091-0. Epub 2013 Nov 18.

5.

Crystal structure of the human TRPV2 channel ankyrin repeat domain.

McCleverty CJ, Koesema E, Patapoutian A, Lesley SA, Kreusch A.

Protein Sci. 2006 Sep;15(9):2201-6. Epub 2006 Aug 1.

6.

Differential regulation of TRPV1, TRPV3, and TRPV4 sensitivity through a conserved binding site on the ankyrin repeat domain.

Phelps CB, Wang RR, Choo SS, Gaudet R.

J Biol Chem. 2010 Jan 1;285(1):731-40. doi: 10.1074/jbc.M109.052548. Epub 2009 Oct 28.

7.

Insights into the roles of conserved and divergent residues in the ankyrin repeats of TRPV ion channels.

Phelps CB, Procko E, Lishko PV, Wang RR, Gaudet R.

Channels (Austin). 2007 May-Jun;1(3):148-51. Epub 2007 Jul 9.

PMID:
18690026
8.

The ankyrin repeats of TRPV1 bind multiple ligands and modulate channel sensitivity.

Lishko PV, Procko E, Jin X, Phelps CB, Gaudet R.

Neuron. 2007 Jun 21;54(6):905-18.

9.

Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.

Lau SY, Procko E, Gaudet R.

J Gen Physiol. 2012 Nov;140(5):541-55. doi: 10.1085/jgp.201210810.

10.

Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.

Garcia-Elias A, Berna-Erro A, Rubio-Moscardo F, Pardo-Pastor C, Mrkonjić S, Sepúlveda RV, Vicente R, González-Nilo F, Valverde MA.

Structure. 2015 Aug 4;23(8):1404-13. doi: 10.1016/j.str.2015.05.018. Epub 2015 Jul 2.

11.

Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C.

Auer-Grumbach M, Olschewski A, Papić L, Kremer H, McEntagart ME, Uhrig S, Fischer C, Fröhlich E, Bálint Z, Tang B, Strohmaier H, Lochmüller H, Schlotter-Weigel B, Senderek J, Krebs A, Dick KJ, Petty R, Longman C, Anderson NE, Padberg GW, Schelhaas HJ, van Ravenswaaij-Arts CM, Pieber TR, Crosby AH, Guelly C.

Nat Genet. 2010 Feb;42(2):160-4. doi: 10.1038/ng.508. Epub 2009 Dec 27.

12.

A TRPV4 channel C-terminal folding recognition domain critical for trafficking and function.

Lei L, Cao X, Yang F, Shi DJ, Tang YQ, Zheng J, Wang K.

J Biol Chem. 2013 Apr 12;288(15):10427-39. doi: 10.1074/jbc.M113.457291. Epub 2013 Mar 2.

13.

Mutations in TRPV4 cause an inherited arthropathy of hands and feet.

Lamandé SR, Yuan Y, Gresshoff IL, Rowley L, Belluoccio D, Kaluarachchi K, Little CB, Botzenhart E, Zerres K, Amor DJ, Cole WG, Savarirayan R, McIntyre P, Bateman JF.

Nat Genet. 2011 Oct 2;43(11):1142-6. doi: 10.1038/ng.945.

PMID:
21964574
14.

Mutations in TRPV4 cause Charcot-Marie-Tooth disease type 2C.

Landouré G, Zdebik AA, Martinez TL, Burnett BG, Stanescu HC, Inada H, Shi Y, Taye AA, Kong L, Munns CH, Choo SS, Phelps CB, Paudel R, Houlden H, Ludlow CL, Caterina MJ, Gaudet R, Kleta R, Fischbeck KH, Sumner CJ.

Nat Genet. 2010 Feb;42(2):170-4. doi: 10.1038/ng.512. Epub 2009 Dec 27.

15.

TRPV4-pathy, a novel channelopathy affecting diverse systems.

Dai J, Cho TJ, Unger S, Lausch E, Nishimura G, Kim OH, Superti-Furga A, Ikegawa S.

J Hum Genet. 2010 Jul;55(7):400-2. doi: 10.1038/jhg.2010.37. Epub 2010 May 27. Review.

PMID:
20505684
16.

Structure of the N-terminal ankyrin repeat domain of the TRPV2 ion channel.

Jin X, Touhey J, Gaudet R.

J Biol Chem. 2006 Sep 1;281(35):25006-10. Epub 2006 Jun 29.

17.

PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4.

Cuajungco MP, Grimm C, Oshima K, D'hoedt D, Nilius B, Mensenkamp AR, Bindels RJ, Plomann M, Heller S.

J Biol Chem. 2006 Jul 7;281(27):18753-62. Epub 2006 Apr 20.

18.

Structural insight into the assembly of TRPV channels.

Huynh KW, Cohen MR, Chakrapani S, Holdaway HA, Stewart PL, Moiseenkova-Bell VY.

Structure. 2014 Feb 4;22(2):260-8. doi: 10.1016/j.str.2013.11.008. Epub 2013 Dec 26.

19.

ATP modulates Ca2+ uptake by TRPV6 and is counteracted by isoform-specific phosphorylation.

Al-Ansary D, Bogeski I, Disteldorf BM, Becherer U, Niemeyer BA.

FASEB J. 2010 Feb;24(2):425-35. doi: 10.1096/fj.09-141481. Epub 2009 Oct 5.

PMID:
19805577
20.

Asparaginyl beta-hydroxylation of proteins containing ankyrin repeat domains influences their stability and function.

Hardy AP, Prokes I, Kelly L, Campbell ID, Schofield CJ.

J Mol Biol. 2009 Oct 2;392(4):994-1006. doi: 10.1016/j.jmb.2009.07.070. Epub 2009 Jul 30.

PMID:
19646994

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