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Items: 1 to 20 of 101

1.

Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos.

Voruganti VS, Higgins PB, Ebbesson SO, Kennish J, Göring HH, Haack K, Laston S, Drigalenko E, Wenger CR, Harris WS, Fabsitz RR, Devereux RB, Maccluer JW, Curran JE, Carless MA, Johnson MP, Moses EK, Blangero J, Umans JG, Howard BV, Cole SA, Comuzzie AG.

Front Genet. 2012 Jun 11;3:86. doi: 10.3389/fgene.2012.00086. eCollection 2012.

2.

Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study.

Zietemann V, Kröger J, Enzenbach C, Jansen E, Fritsche A, Weikert C, Boeing H, Schulze MB.

Br J Nutr. 2010 Dec;104(12):1748-59. doi: 10.1017/S0007114510002916. Epub 2010 Aug 9.

PMID:
20691134
3.

Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.

Al-Hilal M, Alsaleh A, Maniou Z, Lewis FJ, Hall WL, Sanders TA, O'Dell SD; MARINA study team.

J Lipid Res. 2013 Feb;54(2):542-51. doi: 10.1194/jlr.P032276. Epub 2012 Nov 15.

4.

Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease.

Tosi F, Sartori F, Guarini P, Olivieri O, Martinelli N.

Adv Exp Med Biol. 2014;824:61-81. doi: 10.1007/978-3-319-07320-0_7. Review.

PMID:
25038994
5.

Associations between variants of FADS genes and omega-3 and omega-6 milk fatty acids of Canadian Holstein cows.

Ibeagha-Awemu EM, Akwanji KA, Beaudoin F, Zhao X.

BMC Genet. 2014 Feb 17;15:25. doi: 10.1186/1471-2156-15-25.

6.

Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.

Bokor S, Dumont J, Spinneker A, Gonzalez-Gross M, Nova E, Widhalm K, Moschonis G, Stehle P, Amouyel P, De Henauw S, Molnàr D, Moreno LA, Meirhaeghe A, Dallongeville J; HELENA Study Group.

J Lipid Res. 2010 Aug;51(8):2325-33. doi: 10.1194/jlr.M006205. Epub 2010 Apr 28.

7.

DNA methylation in an enhancer region of the FADS cluster is associated with FADS activity in human liver.

Howard TD, Mathias RA, Seeds MC, Herrington DM, Hixson JE, Shimmin LC, Hawkins GA, Sellers M, Ainsworth HC, Sergeant S, Miller LR, Chilton FH.

PLoS One. 2014 May 19;9(5):e97510. doi: 10.1371/journal.pone.0097510. eCollection 2014.

8.

Variation in the FADS1/2 gene cluster alters plasma n-6 PUFA and is weakly associated with hsCRP levels in healthy young adults.

Roke K, Ralston JC, Abdelmagid S, Nielsen DE, Badawi A, El-Sohemy A, Ma DW, Mutch DM.

Prostaglandins Leukot Essent Fatty Acids. 2013 Sep;89(4):257-63. doi: 10.1016/j.plefa.2013.06.003. Epub 2013 Jul 16.

PMID:
23867726
10.

Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.

Reardon HT, Zhang J, Kothapalli KS, Kim AJ, Park WJ, Brenna JT.

Prostaglandins Leukot Essent Fatty Acids. 2012 Jul;87(1):25-33. doi: 10.1016/j.plefa.2012.04.011. Epub 2012 Jun 27.

11.

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.

Rzehak P, Heinrich J, Klopp N, Schaeffer L, Hoff S, Wolfram G, Illig T, Linseisen J.

Br J Nutr. 2009 Jan;101(1):20-6. doi: 10.1017/S0007114508992564. Epub 2008 May 15.

PMID:
18479586
12.

Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.

Merino DM, Johnston H, Clarke S, Roke K, Nielsen D, Badawi A, El-Sohemy A, Ma DW, Mutch DM.

Mol Genet Metab. 2011 Jun;103(2):171-8. doi: 10.1016/j.ymgme.2011.02.012. Epub 2011 Feb 23.

PMID:
21414826
13.

[Desaturases of fatty acids (FADS) and their physiological and clinical implication].

Žák A, Slabý A, Tvrzická E, Jáchymová M, Macášek J, Vecka M, Zeman M, Staňková B.

Cas Lek Cesk. 2016;155(2):15-21. Czech.

PMID:
27088787
14.

A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle.

Nakayama K, Bayasgalan T, Tazoe F, Yanagisawa Y, Gotoh T, Yamanaka K, Ogawa A, Munkhtulga L, Chimedregze U, Kagawa Y, Ishibashi S, Iwamoto S; Jichi Medical University Promotion Team of a Large-scale Human Genome Bank for All over Japan.

Hum Genet. 2010 Jun;127(6):685-90. doi: 10.1007/s00439-010-0815-6. Epub 2010 Apr 3.

PMID:
20364269
15.

Recent insights into the relation of Δ5 desaturase and Δ6 desaturase activity to the development of type 2 diabetes.

Kröger J, Schulze MB.

Curr Opin Lipidol. 2012 Feb;23(1):4-10. doi: 10.1097/MOL.0b013e32834d2dc5. Review.

PMID:
22123669
16.

Genetic variation in APOJ, LPL, and TNFRSF10B affects plasma fatty acid distribution in Alaskan Eskimos.

Voruganti VS, Cole SA, Ebbesson SO, Göring HH, Haack K, Laston S, Wenger CR, Tejero ME, Devereux RB, Fabsitz RR, MacCluer JW, Umans JG, Howard BV, Comuzzie AG.

Am J Clin Nutr. 2010 Jun;91(6):1574-83. doi: 10.3945/ajcn.2009.28927. Epub 2010 Apr 21.

17.

Gene expression of desaturase (FADS1 and FADS2) and Elongase (ELOVL5) enzymes in peripheral blood: association with polyunsaturated fatty acid levels and atopic eczema in 4-year-old children.

Chisaguano AM, Montes R, Pérez-Berezo T, Castellote AI, Guerendiain M, Bustamante M, Morales E, García-Esteban R, Sunyer J, Franch A, López-Sabater MC.

PLoS One. 2013 Oct 22;8(10):e78245. doi: 10.1371/journal.pone.0078245. eCollection 2013.

18.

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease.

Malerba G, Schaeffer L, Xumerle L, Klopp N, Trabetti E, Biscuola M, Cavallari U, Galavotti R, Martinelli N, Guarini P, Girelli D, Olivieri O, Corrocher R, Heinrich J, Pignatti PF, Illig T.

Lipids. 2008 Apr;43(4):289-99. doi: 10.1007/s11745-008-3158-5. Epub 2008 Mar 5.

PMID:
18320251
19.

Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study.

Xie L, Innis SM.

J Nutrigenet Nutrigenomics. 2009;2(4-5):243-50. doi: 10.1159/000255636. Epub 2010 Apr 15.

PMID:
20395685
20.

Lack of association of SNPs from the FADS1-FADS2 gene cluster with major depression or suicidal behavior.

Sublette ME, Vaquero C, Baca-Garcia E, Pachano G, Huang YY, Oquendo MA, Mann JJ.

Psychiatr Genet. 2016 Apr;26(2):81-6. doi: 10.1097/YPG.0000000000000111.

PMID:
26513616
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