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Items: 1 to 20 of 96

1.

St. John's wort significantly increased the systemic exposure and toxicity of methotrexate in rats.

Yang SY, Juang SH, Tsai SY, Chao PD, Hou YC.

Toxicol Appl Pharmacol. 2012 Aug 15;263(1):39-43. doi: 10.1016/j.taap.2012.05.020.

PMID:
22699020
2.

Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients.

Bauer S, Störmer E, Johne A, Krüger H, Budde K, Neumayer HH, Roots I, Mai I.

Br J Clin Pharmacol. 2003 Feb;55(2):203-11.

3.

Life-threatening interaction between the root extract of Pueraria lobata and methotrexate in rats.

Chiang HM, Fang SH, Wen KC, Hsiu SL, Tsai SY, Hou YC, Chi YC, Chao PD.

Toxicol Appl Pharmacol. 2005 Dec 15;209(3):263-8.

PMID:
15936791
4.

Time-course effects of St John's wort on the pharmacokinetics of cyclosporine in dogs: interactions between herbal extracts and drugs.

Fukunaga K, Orito K.

J Vet Pharmacol Ther. 2012 Oct;35(5):446-51. doi: 10.1111/j.1365-2885.2011.01348.x.

PMID:
22091645
5.

Glycyrrhizin and licorice significantly affect the pharmacokinetics of methotrexate in rats.

Lin SP, Tsai SY, Hou YC, Chao PD.

J Agric Food Chem. 2009 Mar 11;57(5):1854-9. doi: 10.1021/jf8029918.

PMID:
19209930
6.

Drug interaction between St John's wort and zolpidem in healthy subjects.

Hojo Y, Echizenya M, Ohkubo T, Shimizu T.

J Clin Pharm Ther. 2011 Dec;36(6):711-5. doi: 10.1111/j.1365-2710.2010.01223.x.

PMID:
21058968
7.

The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity.

Wang Z, Gorski JC, Hamman MA, Huang SM, Lesko LJ, Hall SD.

Clin Pharmacol Ther. 2001 Oct;70(4):317-26.

PMID:
11673747
8.
9.

Pharmacokinetics of the co-administration of boceprevir and St John's wort to male and female healthy volunteers.

Jackson A, D'Avolio A, Moyle G, Bonora S, Di Perri G, Else L, Simiele M, Singh GJ, Back D, Boffito M.

J Antimicrob Chemother. 2014 Jul;69(7):1911-5. doi: 10.1093/jac/dku060.

10.

Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers.

Hebert MF, Park JM, Chen YL, Akhtar S, Larson AM.

J Clin Pharmacol. 2004 Jan;44(1):89-94.

PMID:
14681346
11.

Drug interactions with St. John's Wort (Hypericum perforatum): a review of the clinical evidence.

Izzo AA.

Int J Clin Pharmacol Ther. 2004 Mar;42(3):139-48. Review.

PMID:
15049433
12.

Effects of St. John's wort supplementation on ibuprofen pharmacokinetics.

Bell EC, Ravis WR, Lloyd KB, Stokes TJ.

Ann Pharmacother. 2007 Feb;41(2):229-34.

PMID:
17284505
13.

Effect of St John's wort on imatinib mesylate pharmacokinetics.

Frye RF, Fitzgerald SM, Lagattuta TF, Hruska MW, Egorin MJ.

Clin Pharmacol Ther. 2004 Oct;76(4):323-9.

PMID:
15470331
14.

Inhibitory effect of the herbal antidepressant St. John's wort (Hypericum perforatum) on rat gastric motility.

Capasso R, Borrelli F, Aviello G, Capasso F, Izzo AA.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Feb;376(6):407-14. doi: 10.1007/s00210-007-0230-2.

PMID:
18172613
15.

St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4.

Dürr D, Stieger B, Kullak-Ublick GA, Rentsch KM, Steinert HC, Meier PJ, Fattinger K.

Clin Pharmacol Ther. 2000 Dec;68(6):598-604.

PMID:
11180019
16.

Hyperforin content determines the magnitude of the St John's wort-cyclosporine drug interaction.

Mai I, Bauer S, Perloff ES, Johne A, Uehleke B, Frank B, Budde K, Roots I.

Clin Pharmacol Ther. 2004 Oct;76(4):330-40.

PMID:
15470332
17.

An update on clinical drug interactions with the herbal antidepressant St. John's wort.

Zhou SF, Lai X.

Curr Drug Metab. 2008 Jun;9(5):394-409. Review.

PMID:
18537576
18.

Effect of St John's wort on bone formation in the orthopaedically expanded premaxillary suture in rats: a histological study.

Halicioglu K, Çörekçi B, Akkaş İ, Irgin C, Özan F, Yilmaz F, Türker A.

Eur J Orthod. 2015 Apr;37(2):164-9. doi: 10.1093/ejo/cju028.

19.

Effect of pre-treatment with St John's Wort on nephrotoxicity of cisplatin in rats.

Shibayama Y, Kawachi A, Onimaru S, Tokunaga J, Ikeda R, Nishida K, Kuchiiwa S, Nakagawa S, Takamura N, Motoya T, Takeda Y, Yamada K.

Life Sci. 2007 Jun 20;81(2):103-8.

PMID:
17543347
20.

Minimal effects from developmental exposure to St. John's wort (Hypericum perforatum) in Sprague-Dawley rats.

Cada AM, Hansen DK, LaBorde JB, Ferguson SA.

Nutr Neurosci. 2001;4(2):135-41.

PMID:
11842881
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