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Items: 1 to 20 of 137


Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway.

Gavrilovskaya IN, Gorbunova EE, Mackow ER.

J Virol. 2013 Dec;87(23):12999-3008. doi: 10.1128/JVI.02103-13. Epub 2013 Sep 25.


Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability.

Pepini T, Gorbunova EE, Gavrilovskaya IN, Mackow JE, Mackow ER.

J Virol. 2010 Nov;84(22):11929-36. doi: 10.1128/JVI.01658-10. Epub 2010 Sep 15.


VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability.

Gorbunova EE, Gavrilovskaya IN, Pepini T, Mackow ER.

J Virol. 2011 Mar;85(5):2296-303. doi: 10.1128/JVI.02319-10. Epub 2010 Dec 22.


Slit2-Robo4 receptor responses inhibit ANDV directed permeability of human lung microvascular endothelial cells.

Gorbunova EE, Gavrilovskaya IN, Mackow ER.

Antiviral Res. 2013 Aug;99(2):108-12. doi: 10.1016/j.antiviral.2013.05.004. Epub 2013 May 20.


The Andes Virus Nucleocapsid Protein Directs Basal Endothelial Cell Permeability by Activating RhoA.

Gorbunova EE, Simons MJ, Gavrilovskaya IN, Mackow ER.

MBio. 2016 Oct 25;7(5). pii: e01747-16. doi: 10.1128/mBio.01747-16.


Role of vascular and lymphatic endothelial cells in hantavirus pulmonary syndrome suggests targeted therapeutic approaches.

Mackow ER, Gorbunova EE, Dalrymple NA, Gavrilovskaya IN.

Lymphat Res Biol. 2013 Sep;11(3):128-35. doi: 10.1089/lrb.2013.0006. Epub 2013 Sep 11.


Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses.

Geimonen E, Neff S, Raymond T, Kocer SS, Gavrilovskaya IN, Mackow ER.

Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13837-42. Epub 2002 Oct 4.


Pathogenic hantaviruses direct the adherence of quiescent platelets to infected endothelial cells.

Gavrilovskaya IN, Gorbunova EE, Mackow ER.

J Virol. 2010 May;84(9):4832-9. doi: 10.1128/JVI.02405-09. Epub 2010 Feb 24.


Hantavirus interferon regulation and virulence determinants.

Mackow ER, Dalrymple NA, Cimica V, Matthys V, Gorbunova E, Gavrilovskaya I.

Virus Res. 2014 Jul 17;187:65-71. doi: 10.1016/j.virusres.2013.12.041. Epub 2014 Jan 8.


Andes virus recognition of human and Syrian hamster beta3 integrins is determined by an L33P substitution in the PSI domain.

Matthys VS, Gorbunova EE, Gavrilovskaya IN, Mackow ER.

J Virol. 2010 Jan;84(1):352-60. doi: 10.1128/JVI.01013-09.


Dysregulation of the β3 integrin-VEGFR2 complex in Hantaan virus-directed hyperpermeability upon treatment with VEGF.

Wang W, Zhang Y, Li Y, Pan L, Bai L, Zhuang Y, Huang CX, Wang JP, Yu HT, Wei X, Jiang W, Nan YY, Yang DQ, Su WJ, Wang PZ, Bai XF.

Arch Virol. 2012 Jun;157(6):1051-61. doi: 10.1007/s00705-012-1245-7. Epub 2012 Mar 11.


An innate immunity-regulating virulence determinant is uniquely encoded by the Andes virus nucleocapsid protein.

Cimica V, Dalrymple NA, Roth E, Nasonov A, Mackow ER.

MBio. 2014 Feb 18;5(1). pii: e01088-13. doi: 10.1128/mBio.01088-13.


Host mTORC1 signaling regulates andes virus replication.

McNulty S, Flint M, Nichol ST, Spiropoulou CF.

J Virol. 2013 Jan;87(2):912-22. doi: 10.1128/JVI.02415-12. Epub 2012 Nov 7.


Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability.

Marsac D, García S, Fournet A, Aguirre A, Pino K, Ferres M, Kalergis AM, Lopez-Lastra M, Veas F.

Virol J. 2011 May 13;8:223. doi: 10.1186/1743-422X-8-223.


A novel Sin Nombre virus DNA vaccine and its inclusion in a candidate pan-hantavirus vaccine against hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS).

Hooper JW, Josleyn M, Ballantyne J, Brocato R.

Vaccine. 2013 Sep 13;31(40):4314-21. doi: 10.1016/j.vaccine.2013.07.025. Epub 2013 Jul 24.


Hantavirus pulmonary syndrome.

Macneil A, Nichol ST, Spiropoulou CF.

Virus Res. 2011 Dec;162(1-2):138-47. doi: 10.1016/j.virusres.2011.09.017. Epub 2011 Sep 17. Review.


Hantavirus regulation of endothelial cell functions.

Mackow ER, Gavrilovskaya IN.

Thromb Haemost. 2009 Dec;102(6):1030-41. doi: 10.1160/TH09-09-0640. Review.


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