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Items: 1 to 20 of 117

1.

Mechanistic insights into the dual inhibition strategy for checking Leishmaniasis.

Grover A, Katiyar SP, Jeyakanthan J, Dubey VK, Sundar D.

J Biomol Struct Dyn. 2012;30(4):474-87. doi: 10.1080/07391102.2012.682212. Epub 2012 Jun 12.

PMID:
22694167
2.

A leishmaniasis study: structure-based screening and molecular dynamics mechanistic analysis for discovering potent inhibitors of spermidine synthase.

Grover A, Katiyar SP, Singh SK, Dubey VK, Sundar D.

Biochim Biophys Acta. 2012 Dec;1824(12):1476-83. doi: 10.1016/j.bbapap.2012.05.016. Epub 2012 Jun 8.

PMID:
22684087
3.

Targeting polyamine metabolism for finding new drugs against leishmaniasis: a review.

Ilari A, Fiorillo A, Baiocco P, Poser E, Angiulli G, Colotti G.

Mini Rev Med Chem. 2015;15(3):243-52. Review.

PMID:
25769972
4.

Molecular Modeling and Virtual Screening Approach to Discover Potential Antileishmanial Inhibitors Against Ornithine Decarboxylase.

Pandey RK, Prajapati P, Goyal S, Grover A, Prajapati VK.

Comb Chem High Throughput Screen. 2016;19(10):813-823. doi: 10.2174/1386207319666160907100134.

PMID:
27604958
6.

Effects of bis(benzyl)polyamine analogs on Leishmania donovani promastigotes.

Mukhopadhyay R, Madhubala R.

Exp Parasitol. 1995 Aug;81(1):39-46.

PMID:
7628565
7.

Developing imidazole analogues as potential inhibitor for Leishmania donovani trypanothione reductase: virtual screening, molecular docking, dynamics and ADMET approach.

Pandey RK, Sharma D, Bhatt TK, Sundar S, Prajapati VK.

J Biomol Struct Dyn. 2015;33(12):2541-53. doi: 10.1080/07391102.2015.1085904. Epub 2015 Sep 28.

PMID:
26305585
8.

Mechanistic insights into mode of actions of novel oligopeptidase B inhibitors for combating leishmaniasis.

Goyal S, Grover S, Dhanjal JK, Goyal M, Tyagi C, Chacko S, Grover A.

J Mol Model. 2014 Mar;20(3):2099. doi: 10.1007/s00894-014-2099-6. Epub 2014 Feb 25.

PMID:
24567150
9.
10.

Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.

Dufe VT, Qiu W, Müller IB, Hui R, Walter RD, Al-Karadaghi S.

J Mol Biol. 2007 Oct 12;373(1):167-77. Epub 2007 Aug 2.

PMID:
17822713
11.

Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs.

Roberts SC, Jiang Y, Gasteier J, Frydman B, Marton LJ, Heby O, Ullman B.

Antimicrob Agents Chemother. 2007 Feb;51(2):438-45. Epub 2006 Nov 20.

13.
14.

Polyamine biosynthetic enzymes as drug targets in parasitic protozoa.

Heby O, Roberts SC, Ullman B.

Biochem Soc Trans. 2003 Apr;31(2):415-9. Review.

PMID:
12653650
15.

Ornithine decarboxylase and S-adenosylmethionine decarboxylase in trypanosomatids.

Persson L.

Biochem Soc Trans. 2007 Apr;35(Pt 2):314-7.

PMID:
17371268
16.

Effects of pentamidine on polyamine level and biosynthesis in wild-type, pentamidine-treated, and pentamidine-resistant Leishmania.

Basselin M, Badet-Denisot MA, Lawrence F, Robert-Gero M.

Exp Parasitol. 1997 Mar;85(3):274-82.

PMID:
9085924
17.

Ornithine decarboxylase gene deletion mutants of Leishmania donovani.

Jiang Y, Roberts SC, Jardim A, Carter NS, Shih S, Ariyanayagam M, Fairlamb AH, Ullman B.

J Biol Chem. 1999 Feb 5;274(6):3781-8.

18.

Translational regulation of ornithine decarboxylase and other enzymes of the polyamine pathway.

Shantz LM, Pegg AE.

Int J Biochem Cell Biol. 1999 Jan;31(1):107-22. Review.

PMID:
10216947
19.

Spermidine synthase is required for virulence of Leishmania donovani.

Gilroy C, Olenyik T, Roberts SC, Ullman B.

Infect Immun. 2011 Jul;79(7):2764-9. doi: 10.1128/IAI.00073-11. Epub 2011 May 2.

20.

Mechanistic insights into mode of action of potent natural antagonists of BACE-1 for checking Alzheimer's plaque pathology.

Dhanjal JK, Goyal S, Sharma S, Hamid R, Grover A.

Biochem Biophys Res Commun. 2014 Jan 17;443(3):1054-9. doi: 10.1016/j.bbrc.2013.12.088. Epub 2013 Dec 21.

PMID:
24365147

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