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Items: 1 to 20 of 168


TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction.

Doyle EL, Booher NJ, Standage DS, Voytas DF, Brendel VP, Vandyk JK, Bogdanove AJ.

Nucleic Acids Res. 2012 Jul;40(Web Server issue):W117-22. doi: 10.1093/nar/gks608. Epub 2012 Jun 12.


Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting.

Cermak T, Doyle EL, Christian M, Wang L, Zhang Y, Schmidt C, Baller JA, Somia NV, Bogdanove AJ, Voytas DF.

Nucleic Acids Res. 2011 Jul;39(12):e82. doi: 10.1093/nar/gkr218. Epub 2011 Apr 14. Erratum in: Nucleic Acids Res. 2011 Sep 1;39(17):7879.


TAL effectors: highly adaptable phytobacterial virulence factors and readily engineered DNA-targeting proteins.

Doyle EL, Stoddard BL, Voytas DF, Bogdanove AJ.

Trends Cell Biol. 2013 Aug;23(8):390-8. doi: 10.1016/j.tcb.2013.04.003. Epub 2013 May 23. Review.


Targeting G with TAL effectors: a comparison of activities of TALENs constructed with NN and NK repeat variable di-residues.

Christian ML, Demorest ZL, Starker CG, Osborn MJ, Nyquist MD, Zhang Y, Carlson DF, Bradley P, Bogdanove AJ, Voytas DF.

PLoS One. 2012;7(9):e45383. doi: 10.1371/journal.pone.0045383. Epub 2012 Sep 24.


Tools for TAL effector design and target prediction.

Booher NJ, Bogdanove AJ.

Methods. 2014 Sep;69(2):121-7. doi: 10.1016/j.ymeth.2014.06.006. Epub 2014 Jun 27. Review.


Computational predictions provide insights into the biology of TAL effector target sites.

Grau J, Wolf A, Reschke M, Bonas U, Posch S, Boch J.

PLoS Comput Biol. 2013;9(3):e1002962. doi: 10.1371/journal.pcbi.1002962. Epub 2013 Mar 14.


SAPTA: a new design tool for improving TALE nuclease activity.

Lin Y, Fine EJ, Zheng Z, Antico CJ, Voit RA, Porteus MH, Cradick TJ, Bao G.

Nucleic Acids Res. 2014 Apr;42(6):e47. doi: 10.1093/nar/gkt1363. Epub 2014 Jan 16.


A TAL effector repeat architecture for frameshift binding.

Richter A, Streubel J, Bl├╝cher C, Szurek B, Reschke M, Grau J, Boch J.

Nat Commun. 2014 Mar 11;5:3447. doi: 10.1038/ncomms4447.


Programmable DNA-binding proteins from Burkholderia provide a fresh perspective on the TALE-like repeat domain.

de Lange O, Wolf C, Dietze J, Elsaesser J, Morbitzer R, Lahaye T.

Nucleic Acids Res. 2014 Jun;42(11):7436-49. doi: 10.1093/nar/gku329. Epub 2014 May 3.


TAL effector specificity for base 0 of the DNA target is altered in a complex, effector- and assay-dependent manner by substitutions for the tryptophan in cryptic repeat -1.

Doyle EL, Hummel AW, Demorest ZL, Starker CG, Voytas DF, Bradley P, Bogdanove AJ.

PLoS One. 2013 Dec 3;8(12):e82120. doi: 10.1371/journal.pone.0082120. eCollection 2013.


Engineering synthetic TAL effectors with orthogonal target sites.

Garg A, Lohmueller JJ, Silver PA, Armel TZ.

Nucleic Acids Res. 2012 Aug;40(15):7584-95. doi: 10.1093/nar/gks404. Epub 2012 May 11.


TAL effectors: tools for DNA targeting.

Jankele R, Svoboda P.

Brief Funct Genomics. 2014 Sep;13(5):409-19. doi: 10.1093/bfgp/elu013. Epub 2014 Jun 6.


Assembly of custom TALE-type DNA binding domains by modular cloning.

Morbitzer R, Elsaesser J, Hausner J, Lahaye T.

Nucleic Acids Res. 2011 Jul;39(13):5790-9. doi: 10.1093/nar/gkr151. Epub 2011 Mar 18.


Mojo Hand, a TALEN design tool for genome editing applications.

Neff KL, Argue DP, Ma AC, Lee HB, Clark KJ, Ekker SC.

BMC Bioinformatics. 2013 Jan 16;14:1. doi: 10.1186/1471-2105-14-1.


The last half-repeat of transcription activator-like effector (TALE) is dispensable and thereby TALE-based technology can be simplified.

Zheng CK, Wang CL, Zhang XP, Wang FJ, Qin TF, Zhao KJ.

Mol Plant Pathol. 2014 Sep;15(7):690-7. doi: 10.1111/mpp.12125. Epub 2014 Apr 10.


ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool.

Sander JD, Maeder ML, Reyon D, Voytas DF, Joung JK, Dobbs D.

Nucleic Acids Res. 2010 Jul;38(Web Server issue):W462-8. doi: 10.1093/nar/gkq319. Epub 2010 Apr 30.


A simple cipher governs DNA recognition by TAL effectors.

Moscou MJ, Bogdanove AJ.

Science. 2009 Dec 11;326(5959):1501. doi: 10.1126/science.1178817.


Rapid and highly efficient construction of TALE-based transcriptional regulators and nucleases for genome modification.

Li L, Piatek MJ, Atef A, Piatek A, Wibowo A, Fang X, Sabir JS, Zhu JK, Mahfouz MM.

Plant Mol Biol. 2012 Mar;78(4-5):407-16. doi: 10.1007/s11103-012-9875-4. Epub 2012 Jan 22.


Assembly of designer TAL effectors by Golden Gate cloning.

Weber E, Gruetzner R, Werner S, Engler C, Marillonnet S.

PLoS One. 2011;6(5):e19722. doi: 10.1371/journal.pone.0019722. Epub 2011 May 19.


Breaking the code of DNA binding specificity of TAL-type III effectors.

Boch J, Scholze H, Schornack S, Landgraf A, Hahn S, Kay S, Lahaye T, Nickstadt A, Bonas U.

Science. 2009 Dec 11;326(5959):1509-12. doi: 10.1126/science.1178811.

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