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Items: 1 to 20 of 221

1.

Mixed-1,10-phenanthroline-Cu(II) complexes: synthesis, cytotoxic activity versus hematological and solid tumor cells and complex formation equilibria with glutathione.

Pivetta T, Isaia F, Verani G, Cannas C, Serra L, Castellano C, Demartin F, Pilla F, Manca M, Pani A.

J Inorg Biochem. 2012 Sep;114:28-37. doi: 10.1016/j.jinorgbio.2012.04.017. Epub 2012 May 4.

PMID:
22687563
2.

Novel copper(II) complexes as new promising antitumour agents. A crystal structure of [Cu(1,10-phenanthroline-5,6-dione)2(OH2)(OClO3)](ClO4).

Pivetta T, Trudu F, Valletta E, Isaia F, Castellano C, Demartin F, Tuveri R, Vascellari S, Pani A.

J Inorg Biochem. 2014 Dec;141:103-113. doi: 10.1016/j.jinorgbio.2014.08.011. Epub 2014 Sep 4.

PMID:
25238635
3.

Synthesis, structural characterization and cytotoxic activity of ternary copper(II)-dipeptide-phenanthroline complexes. A step towards the development of new copper compounds for the treatment of cancer.

Iglesias S, Alvarez N, Torre MH, Kremer E, Ellena J, Ribeiro RR, Barroso RP, Costa-Filho AJ, Kramer MG, Facchin G.

J Inorg Biochem. 2014 Oct;139:117-23. doi: 10.1016/j.jinorgbio.2014.06.007. Epub 2014 Jun 17.

PMID:
25033418
4.

Ferrocene-conjugated L-tryptophan copper(II) complexes of phenanthroline bases showing DNA photocleavage activity and cytotoxicity.

Goswami TK, Chakravarthi BV, Roy M, Karande AA, Chakravarty AR.

Inorg Chem. 2011 Sep 5;50(17):8452-64. doi: 10.1021/ic201028e. Epub 2011 Jul 28.

PMID:
21797197
5.

Nitroimidazole and glucosamine conjugated heteroscorpionate ligands and related copper(II) complexes. Syntheses, biological activity and XAS studies.

Pellei M, Papini G, Trasatti A, Giorgetti M, Tonelli D, Minicucci M, Marzano C, Gandin V, Aquilanti G, Dolmella A, Santini C.

Dalton Trans. 2011 Oct 14;40(38):9877-88. doi: 10.1039/c1dt10486a. Epub 2011 Jun 28.

PMID:
21709917
6.

Two new ternary complexes of copper(II) with tetracycline or doxycycline and 1,10-phenanthroline and their potential as antitumoral: cytotoxicity and DNA cleavage.

Silva PP, Guerra W, Silveira JN, Ferreira AM, Bortolotto T, Fischer FL, Terenzi H, Neves A, Pereira-Maia EC.

Inorg Chem. 2011 Jul 18;50(14):6414-24. doi: 10.1021/ic101791r. Epub 2011 Jun 21.

PMID:
21692452
7.

Synthesis, crystal structure and biological activities of a novel amidrazone derivative and its copper(II) complex--a potential antitumor drug.

Mazur L, Modzelewska-Banachiewicz B, Paprocka R, Zimecki M, Wawrzyniak UE, Kutkowska J, Ziółkowska G.

J Inorg Biochem. 2012 Sep;114:55-64. doi: 10.1016/j.jinorgbio.2012.04.021. Epub 2012 May 10.

PMID:
22694858
8.

Syntheses and crystal structures of tetracopper(II) complexes bridged by asymmetric N,N'-bis(substituted)oxamides: Molecular docking, DNA-binding and in vitro anticancer activity.

Li XJ, Zheng K, Wang LD, Li YT, Wu ZY, Yan CW.

J Inorg Biochem. 2013 Nov;128:97-107. doi: 10.1016/j.jinorgbio.2013.07.027. Epub 2013 Jul 23.

PMID:
23948578
9.
10.

Synthesis, crystal structures and spectroscopy of meclofenamic acid and its metal complexes with manganese(II), copper(II), zinc(II) and cadmium(II). Antiproliferative and superoxide dismutase activity.

Kovala-Demertzi D, Staninska M, Garcia-Santos I, Castineiras A, Demertzis MA.

J Inorg Biochem. 2011 Sep;105(9):1187-95. doi: 10.1016/j.jinorgbio.2011.05.025. Epub 2011 Jun 13.

PMID:
21718655
11.

Cu(II) complexes with co-planar [Cu(II)(N-N)(HIMC⁻)], their anti-cancer activities, ΔG, ΔE and solid luminescence.

Cheng YF, Lu XM, Wang G.

Dalton Trans. 2014 Apr 14;43(14):5357-63. doi: 10.1039/c3dt53221f.

PMID:
24519174
12.

Mixed ligand copper(II) complexes of N,N-bis(benzimidazol-2-ylmethyl)amine (BBA) with diimine co-ligands: efficient chemical nuclease and protease activities and cytotoxicity.

Loganathan R, Ramakrishnan S, Suresh E, Riyasdeen A, Akbarsha MA, Palaniandavar M.

Inorg Chem. 2012 May 21;51(10):5512-32. doi: 10.1021/ic2017177. Epub 2012 May 4.

PMID:
22559171
13.
14.

DNA binding, nuclease activity, DNA photocleavage and cytotoxic properties of Cu(II) complexes of N-substituted sulfonamides.

García-Giménez JL, Hernández-Gil J, Martínez-Ruíz A, Castiñeiras A, Liu-González M, Pallardó FV, Borrás J, Alzuet Piña G.

J Inorg Biochem. 2013 Apr;121:167-78. doi: 10.1016/j.jinorgbio.2013.01.003. Epub 2013 Jan 11.

PMID:
23384854
15.

Synthesis, structural characterization, formation constants and in vitro cytotoxicity of phenanthroline and imidazolidine-2-thione copper(II) complexes.

Pivetta T, Cannas MD, Demartin F, Castellano C, Vascellari S, Verani G, Isaia F.

J Inorg Biochem. 2011 Mar;105(3):329-38. doi: 10.1016/j.jinorgbio.2010.11.017. Epub 2010 Nov 30.

PMID:
21421120
16.

Mixed copper-platinum complex formation could explain synergistic antiproliferative effect exhibited by binary mixtures of cisplatin and copper-1,10-phenanthroline compounds: An ESI-MS study.

Pivetta T, Lallai V, Valletta E, Trudu F, Isaia F, Perra D, Pinna E, Pani A.

J Inorg Biochem. 2015 Oct;151:107-14. doi: 10.1016/j.jinorgbio.2015.05.004. Epub 2015 May 14.

PMID:
26021964
17.

Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and resistant cancer cell lines.

O'Connor M, Kellett A, McCann M, Rosair G, McNamara M, Howe O, Creaven BS, McClean S, Kia AF, O'Shea D, Devereux M.

J Med Chem. 2012 Mar 8;55(5):1957-68. doi: 10.1021/jm201041d. Epub 2012 Feb 28.

PMID:
22313179
18.

Synthesis and structure of new tetracopper(II) complexes bridged by 2-{N'-[2-(dimethylamino)ethyl]oxamido}benzoate: DNA-binding and anticancer activity.

Zheng YJ, Li XW, Li YT, Wu ZY, Yan CW.

J Photochem Photobiol B. 2012 Sep 3;114:27-37. doi: 10.1016/j.jphotobiol.2012.05.004. Epub 2012 May 29.

PMID:
22704662
19.

Synthesis, characterization, and antitumor activity of unusual pseudo five coordinate gold(III) complexes: distinct cytotoxic mechanism or expensive ligand delivery systems?

Olsen PM, Ruiz C, Lussier D, Le BK, Angel N, Smith M, Hwang CB, Khatib R, Jenkins J, Adams K, Getcher J, Tham F, Chen ZG, Wilson EH, Eichler JF.

J Inorg Biochem. 2014 Dec;141:121-131. doi: 10.1016/j.jinorgbio.2014.08.014. Epub 2014 Sep 6.

PMID:
25243390
20.

Self-assembly of novel molecular complexes of 1,10-phenanthroline and 5-amino-1,10-phenanthroline and evaluation of their in vitro antitumour activity.

Kaloyanov N, Alexandrova R, Wesselinova DW, Mayer-Figge H, Sheldrick WS, Dimitrov GD.

Eur J Med Chem. 2011 Jun;46(6):1992-6. doi: 10.1016/j.ejmech.2011.02.018. Epub 2011 Mar 3.

PMID:
21474217

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