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Heterozygosity for the proteasomal Psmc1 ATPase is insufficient to cause neuropathology in mouse brain, but causes cell cycle defects in mouse embryonic fibroblasts.

Rezvani N, Elkharaz J, Lawler K, Mee M, Mayer RJ, Bedford L.

Neurosci Lett. 2012 Jul 19;521(2):130-5. doi: 10.1016/j.neulet.2012.05.070. Epub 2012 Jun 5.


Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

Bedford L, Hay D, Devoy A, Paine S, Powe DG, Seth R, Gray T, Topham I, Fone K, Rezvani N, Mee M, Soane T, Layfield R, Sheppard PW, Ebendal T, Usoskin D, Lowe J, Mayer RJ.

J Neurosci. 2008 Aug 13;28(33):8189-98. doi: 10.1523/JNEUROSCI.2218-08.2008.


PSMC1 Gene in Parkinson's Disease.

Gómez-Garre P, Jesús S, Carrillo F, Cáceres-Redondo MT, Bernal-Bernal I, Carballo M, Gao L, Mir P.

Eur Neurol. 2012;68(4):193-8. doi: 10.1159/000339003. Epub 2012 Aug 29.


TOPORS, a Dual E3 Ubiquitin and Sumo1 Ligase, Interacts with 26 S Protease Regulatory Subunit 4, Encoded by the PSMC1 Gene.

Czub B, Shah AZ, Alfano G, Kruczek PM, Chakarova CF, Bhattacharya SS.

PLoS One. 2016 Feb 12;11(2):e0148678. doi: 10.1371/journal.pone.0148678. eCollection 2016.


NADH binds and stabilizes the 26S proteasomes independent of ATP.

Tsvetkov P, Myers N, Eliav R, Adamovich Y, Hagai T, Adler J, Navon A, Shaul Y.

J Biol Chem. 2014 Apr 18;289(16):11272-81. doi: 10.1074/jbc.M113.537175. Epub 2014 Mar 4.


Pale body-like inclusion formation and neurodegeneration following depletion of 26S proteasomes in mouse brain neurones are independent of α-synuclein.

Paine SM, Anderson G, Bedford K, Lawler K, Mayer RJ, Lowe J, Bedford L.

PLoS One. 2013;8(1):e54711. doi: 10.1371/journal.pone.0054711. Epub 2013 Jan 30.


Global changes to the ubiquitin system in Huntington's disease.

Bennett EJ, Shaler TA, Woodman B, Ryu KY, Zaitseva TS, Becker CH, Bates GP, Schulman H, Kopito RR.

Nature. 2007 Aug 9;448(7154):704-8.


Diverse polyubiquitin chains accumulate following 26S proteasomal dysfunction in mammalian neurones.

Bedford L, Layfield R, Mayer RJ, Peng J, Xu P.

Neurosci Lett. 2011 Mar 10;491(1):44-7. doi: 10.1016/j.neulet.2010.12.064. Epub 2011 Jan 5.


Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression.

Fujii T, Ueda T, Nagata S, Fukunaga R.

J Biol Chem. 2010 Sep 24;285(39):30214-23. doi: 10.1074/jbc.M110.104513. Epub 2010 Jul 7.


Sperm-surface ATP in boar spermatozoa is required for fertilization: relevance to sperm proteasomal function.

Yi YJ, Park CS, Kim ES, Song ES, Jeong JH, Sutovsky P.

Syst Biol Reprod Med. 2009 Mar-Apr;55(2):85-96. doi: 10.1080/19396360802699074.


Activation of a novel ubiquitin-independent proteasome pathway when RNA polymerase II encounters a protein roadblock.

Ban Y, Ho CW, Lin RK, Lyu YL, Liu LF.

Mol Cell Biol. 2013 Oct;33(20):4008-16. doi: 10.1128/MCB.00403-13. Epub 2013 Aug 12.


The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other--or not?

Bedford L, Paine S, Rezvani N, Mee M, Lowe J, Mayer RJ.

Autophagy. 2009 Feb;5(2):224-7. Epub 2009 Feb 13.


Effects of tumor necrosis factor-alpha on the 26S proteasome and 19S regulator in skeletal muscle of severely scalded mice.

Tan Y, Peng X, Wang F, You Z, Dong Y, Wang S.

J Burn Care Res. 2006 Mar-Apr;27(2):226-33.


PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes.

Haddock CJ, Blomenkamp K, Gautam M, James J, Mielcarska J, Gogol E, Teckman J, Skowyra D.

PLoS One. 2014 Sep 11;9(9):e106371. doi: 10.1371/journal.pone.0106371. eCollection 2014.


Mapping, expression, and association study of the bovine PSMC1 gene.

Guo H, Liu WS, Takasuga A, Eyer K, Landrito E, Xu SZ, Gao X, Ren HY.

Biochem Genet. 2008 Jun;46(5-6):347-55. doi: 10.1007/s10528-008-9151-0.


Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury.

Wang S, Ni HM, Dorko K, Kumer SC, Schmitt TM, Nawabi A, Komatsu M, Huang H, Ding WX.

Oncotarget. 2016 Apr 5;7(14):17681-98. doi: 10.18632/oncotarget.6893.


Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases.

Park Y, Hwang YP, Lee JS, Seo SH, Yoon SK, Yoon JB.

Mol Cell Biol. 2005 May;25(9):3842-53.


Erythropoietic defect associated with reduced cell proliferation in mice lacking the 26S proteasome shuttling factor Rad23b.

Bergink S, Theil AF, Toussaint W, De Cuyper IM, Kulu DI, Clapes T, van der Linden R, Demmers JA, Mul EP, van Alphen FP, Marteijn JA, van Gent T, Maas A, Robin C, Philipsen S, Vermeulen W, Mitchell JR, Gutiérrez L.

Mol Cell Biol. 2013 Oct;33(19):3879-92. doi: 10.1128/MCB.05772-11. Epub 2013 Jul 29.


Ubiquitin-independent degradation of cell-cycle inhibitors by the REGgamma proteasome.

Chen X, Barton LF, Chi Y, Clurman BE, Roberts JM.

Mol Cell. 2007 Jun 22;26(6):843-52.

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