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Items: 1 to 20 of 87


Tumour cell generation of inducible regulatory T-cells in multiple myeloma is contact-dependent and antigen-presenting cell-independent.

Feyler S, Scott GB, Parrish C, Jarmin S, Evans P, Short M, McKinley K, Selby PJ, Cook G.

PLoS One. 2012;7(5):e35981. doi: 10.1371/journal.pone.0035981. Epub 2012 May 29.


Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta.

Scholzen A, Mittag D, Rogerson SJ, Cooke BM, Plebanski M.

PLoS Pathog. 2009 Aug;5(8):e1000543. doi: 10.1371/journal.ppat.1000543. Epub 2009 Aug 14.


Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.

Baratelli F, Lin Y, Zhu L, Yang SC, Heuzé-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM.

J Immunol. 2005 Aug 1;175(3):1483-90.


Extracorporeal photochemotherapy is accompanied by increasing levels of circulating CD4+CD25+GITR+Foxp3+CD62L+ functional regulatory T-cells in patients with graft-versus-host disease.

Biagi E, Di Biaso I, Leoni V, Gaipa G, Rossi V, Bugarin C, Renoldi G, Parma M, Balduzzi A, Perseghin P, Biondi A.

Transplantation. 2007 Jul 15;84(1):31-9.


TGF-beta1 modulates Foxp3 expression and regulatory activity in distinct CD4+ T cell subsets.

Pyzik M, Piccirillo CA.

J Leukoc Biol. 2007 Aug;82(2):335-46. Epub 2007 May 2.


Myeloma cells act as tolerogenic antigen-presenting cells and induce regulatory T cells in vitro.

Frassanito MA, Ruggieri S, Desantis V, Di Marzo L, Leone P, Racanelli V, Fumarulo R, Dammacco F, Vacca A.

Eur J Haematol. 2015 Jul;95(1):65-74. doi: 10.1111/ejh.12481. Epub 2015 Feb 23.


Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

Ko K, Yamazaki S, Nakamura K, Nishioka T, Hirota K, Yamaguchi T, Shimizu J, Nomura T, Chiba T, Sakaguchi S.

J Exp Med. 2005 Oct 3;202(7):885-91. Epub 2005 Sep 26. Erratum in: J Exp Med. 2012 Feb 13;209(2):423.


Endothelial cells augment the suppressive function of CD4+ CD25+ Foxp3+ regulatory T cells: involvement of programmed death-1 and IL-10.

Bedke T, Pretsch L, Karakhanova S, Enk AH, Mahnke K.

J Immunol. 2010 May 15;184(10):5562-70. doi: 10.4049/jimmunol.0902458. Epub 2010 Apr 9.


Dendritic cells partially abrogate the regulatory activity of CD4+CD25+ T cells present in the human peripheral blood.

Ahn JS, Krishnadas DK, Agrawal B.

Int Immunol. 2007 Mar;19(3):227-37. Epub 2007 Feb 7.


Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells.

Vocanson M, Rozieres A, Hennino A, Poyet G, Gaillard V, Renaudineau S, Achachi A, Benetiere J, Kaiserlian D, Dubois B, Nicolas JF.

J Allergy Clin Immunol. 2010 Aug;126(2):280-9, 289.e1-7. doi: 10.1016/j.jaci.2010.05.022. Epub 2010 Jul 10.


Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment.

Bergmann C, Strauss L, Zeidler R, Lang S, Whiteside TL.

Cancer Immunol Immunother. 2007 Sep;56(9):1429-42. Epub 2007 Jan 31.


Murine bone marrow chimeras developing autoimmunity after CTLA-4-blockade show an expansion of T regulatory cells with an activated cytokine profile.

De Somer L, Fevery S, Bullens DM, Rutgeerts O, Lenaerts C, Mathieu C, Boon L, Kasran A, Waer M, Billiau AD.

Immunol Lett. 2010 Sep 6;133(1):49-53. doi: 10.1016/j.imlet.2010.06.005. Epub 2010 Jun 18.


CD4(+)CD25(+)FoxP3(+) regulatory T cells are increased whilst CD3(+)CD4(-)CD8(-)alphabetaTCR(+) Double Negative T cells are decreased in the peripheral blood of patients with multiple myeloma which correlates with disease burden.

Feyler S, von Lilienfeld-Toal M, Jarmin S, Marles L, Rawstron A, Ashcroft AJ, Owen RG, Selby PJ, Cook G.

Br J Haematol. 2009 Mar;144(5):686-95. doi: 10.1111/j.1365-2141.2008.07530.x. Epub 2008 Dec 26.


mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function.

Zeng H, Yang K, Cloer C, Neale G, Vogel P, Chi H.

Nature. 2013 Jul 25;499(7459):485-90. doi: 10.1038/nature12297. Epub 2013 Jun 30.


Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells.

Di Caro V, D'Anneo A, Phillips B, Engman C, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N.

Clin Exp Immunol. 2011 Jul;165(1):60-76. doi: 10.1111/j.1365-2249.2011.04334.x. Epub 2011 Mar 17.


Induction of contact-dependent CD8(+) regulatory T cells through stimulation with staphylococcal and streptococcal superantigens.

Taylor AL, Cross EL, Llewelyn MJ.

Immunology. 2012 Feb;135(2):158-67. doi: 10.1111/j.1365-2567.2011.03529.x.


CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells.

Liu T, Soong L, Liu G, König R, Chopra AK.

Biol Direct. 2009 Oct 23;4:40. doi: 10.1186/1745-6150-4-40.


FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions.

Ahmadzadeh M, Felipe-Silva A, Heemskerk B, Powell DJ Jr, Wunderlich JR, Merino MJ, Rosenberg SA.

Blood. 2008 Dec 15;112(13):4953-60. doi: 10.1182/blood-2008-06-163048. Epub 2008 Sep 26.


ICOS mediates the generation and function of CD4+CD25+Foxp3+ regulatory T cells conveying respiratory tolerance.

Busse M, Krech M, Meyer-Bahlburg A, Hennig C, Hansen G.

J Immunol. 2012 Aug 15;189(4):1975-82. doi: 10.4049/jimmunol.1103581. Epub 2012 Jul 18.

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