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Items: 1 to 20 of 101

1.

A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome.

Clarke G, McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG.

Front Pharmacol. 2012 May 21;3:90. doi: 10.3389/fphar.2012.00090. eCollection 2012.

2.

Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort.

Clarke G, Fitzgerald P, Cryan JF, Cassidy EM, Quigley EM, Dinan TG.

BMC Gastroenterol. 2009 Jan 20;9:6. doi: 10.1186/1471-230X-9-6.

3.

Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-like Receptor Stimulation in Peripheral Monocytes.

Orhan F, Bhat M, Sandberg K, Ståhl S, Piehl F; Karolinska Schizophrenia Project (KaSP) consortium, Svensson C, Erhardt S, Schwieler L.

Scand J Immunol. 2016 Nov;84(5):262-271. doi: 10.1111/sji.12479.

4.

Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome.

Christmas DM, Badawy AA, Hince D, Davies SJ, Probert C, Creed T, Smithson J, Afzal M, Nutt DJ, Potokar JP.

Nutr Res. 2010 Oct;30(10):678-88. doi: 10.1016/j.nutres.2010.09.009.

PMID:
21056283
5.

Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity.

Fitzgerald P, Cassidy Eugene M, Clarke G, Scully P, Barry S, Quigley Eamonn MM, Shanahan F, Cryan J, Dinan Timothy G.

Neurogastroenterol Motil. 2008 Dec;20(12):1291-7. doi: 10.1111/j.1365-2982.2008.01195.x. Epub 2008 Sep 24.

PMID:
18823288
6.

Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome.

Kennedy PJ, Allen AP, O'Neill A, Quigley EM, Cryan JF, Dinan TG, Clarke G.

Psychopharmacology (Berl). 2015 Apr;232(8):1357-71. doi: 10.1007/s00213-014-3767-z. Epub 2014 Oct 23.

PMID:
25338777
7.

Decreased levels of kynurenic acid in the intestinal mucosa of IBS patients: relation to serotonin and psychological state.

Keszthelyi D, Troost FJ, Jonkers DM, Kruimel JW, Leue C, Masclee AA.

J Psychosom Res. 2013 Jun;74(6):501-4. doi: 10.1016/j.jpsychores.2013.01.008. Epub 2013 Feb 15.

8.

The dysfunctional innate immune response triggered by Toll-like receptor activation is restored by TLR7/TLR8 and TLR9 ligands in cutaneous lichen planus.

Domingues R, de Carvalho GC, da Silva Oliveira LM, Futata Taniguchi E, Zimbres JM, Aoki V, da Silva Duarte AJ, Sato MN.

Br J Dermatol. 2015 Jan;172(1):48-55. doi: 10.1111/bjd.13214. Epub 2014 Nov 20.

PMID:
24976336
9.

Toll-like receptor mRNA expression is selectively increased in the colonic mucosa of two animal models relevant to irritable bowel syndrome.

McKernan DP, Nolan A, Brint EK, O'Mahony SM, Hyland NP, Cryan JF, Dinan TG.

PLoS One. 2009 Dec 9;4(12):e8226. doi: 10.1371/journal.pone.0008226.

10.

Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation.

Hughes MM, Carballedo A, McLoughlin DM, Amico F, Harkin A, Frodl T, Connor TJ.

Brain Behav Immun. 2012 Aug;26(6):979-87. doi: 10.1016/j.bbi.2012.05.010. Epub 2012 Jun 6.

PMID:
22683764
11.

Kynurenine pathway in psychosis: evidence of increased tryptophan degradation.

Barry S, Clarke G, Scully P, Dinan TG.

J Psychopharmacol. 2009 May;23(3):287-94. doi: 10.1177/0269881108089583. Epub 2008 Jun 18.

PMID:
18562404
12.
13.

Increased TLR2 expression on blood monocytes in irritable bowel syndrome patients.

Ohman L, Lindmark AC, Isaksson S, Posserud I, Strid H, Sjövall H, Simrén M.

Eur J Gastroenterol Hepatol. 2012 Apr;24(4):398-405. doi: 10.1097/MEG.0b013e3283503f39.

PMID:
22273988
14.

Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.

Miller CL, Llenos IC, Cwik M, Walkup J, Weis S.

Neurochem Int. 2008 May;52(6):1297-303. doi: 10.1016/j.neuint.2008.01.013. Epub 2008 Feb 2.

PMID:
18328600
15.

Tryptophan degradation in multiple trauma patients: survivors compared with non-survivors.

Ploder M, Spittler A, Schroecksnadel K, Neurauter G, Pelinka LE, Roth E, Fuchs D.

Clin Sci (Lond). 2009 Apr;116(7):593-8. doi: 10.1042/CS20080319.

PMID:
18986303
16.

Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome.

Cenac N, Bautzova T, Le Faouder P, Veldhuis NA, Poole DP, Rolland C, Bertrand J, Liedtke W, Dubourdeau M, Bertrand-Michel J, Zecchi L, Stanghellini V, Bunnett NW, Barbara G, Vergnolle N.

Gastroenterology. 2015 Aug;149(2):433-44.e7. doi: 10.1053/j.gastro.2015.04.011. Epub 2015 Apr 22.

PMID:
25911511
18.

Ongoing episode of major depressive disorder is not associated with elevated plasma levels of kynurenine pathway markers.

Dahl J, Andreassen OA, Verkerk R, Malt UF, Sandvik L, Brundin L, Ormstad H.

Psychoneuroendocrinology. 2015 Jun;56:12-22. doi: 10.1016/j.psyneuen.2015.02.011. Epub 2015 Feb 25.

PMID:
25770856
19.

Longitudinal study of tryptophan degradation during and after pregnancy.

Schröcksnadel K, Widner B, Bergant A, Neurauter G, Schennach H, Schröcksnadel H, Fuchs D.

Life Sci. 2003 Jan 3;72(7):785-93.

PMID:
12479977
20.

Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock.

Schefold JC, Zeden JP, Pschowski R, Hammoud B, Fotopoulou C, Hasper D, Fusch G, Von Haehling S, Volk HD, Meisel C, Schütt C, Reinke P.

Scand J Infect Dis. 2010 Mar;42(3):164-71. doi: 10.3109/00365540903405768.

PMID:
19958238

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