Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 134


Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.

Chantrathammachart P, Mackman N, Sparkenbaugh E, Wang JG, Parise LV, Kirchhofer D, Key NS, Pawlinski R.

Blood. 2012 Jul 19;120(3):636-46. doi: 10.1182/blood-2012-04-424143.


Excess of heme induces tissue factor-dependent activation of coagulation in mice.

Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R.

Haematologica. 2015 Mar;100(3):308-14. doi: 10.3324/haematol.2014.114728.


Plasma levels of tissue factor and soluble E-selectin in sickle cell disease: relationship to genotype and to inflammation.

Mohan JS, Lip GY, Wright J, Bareford D, Blann AD.

Blood Coagul Fibrinolysis. 2005 Apr;16(3):209-14.


Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease.

Sparkenbaugh EM, Chantrathammachart P, Mickelson J, van Ryn J, Hebbel RP, Monroe DM, Mackman N, Key NS, Pawlinski R.

Blood. 2014 Mar 13;123(11):1747-56. doi: 10.1182/blood-2013-08-523936.


Transgenic sickle mice have vascular inflammation.

Belcher JD, Bryant CJ, Nguyen J, Bowlin PR, Kielbik MC, Bischof JC, Hebbel RP, Vercellotti GM.

Blood. 2003 May 15;101(10):3953-9.


Coagulation activation and inflammation in sickle cell disease-associated pulmonary hypertension.

Ataga KI, Moore CG, Hillery CA, Jones S, Whinna HC, Strayhorn D, Sohier C, Hinderliter A, Parise LV, Orringer EP.

Haematologica. 2008 Jan;93(1):20-6. doi: 10.3324/haematol.11763.


Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice.

Pawlinski R, Wang JG, Owens AP 3rd, Williams J, Antoniak S, Tencati M, Luther T, Rowley JW, Low EN, Weyrich AS, Mackman N.

Blood. 2010 Aug 5;116(5):806-14. doi: 10.1182/blood-2009-12-259267.


Endothelial nitric oxide synthase and nitric oxide regulate endothelial tissue factor expression in vivo in the sickle transgenic mouse.

Solovey A, Kollander R, Milbauer LC, Abdulla F, Chen Y, Kelm RJ Jr, Hebbel RP.

Am J Hematol. 2010 Jan;85(1):41-5. doi: 10.1002/ajh.21582.


The fucosylation inhibitor, 2-fluorofucose, inhibits vaso-occlusion, leukocyte-endothelium interactions and NF-ĸB activation in transgenic sickle mice.

Belcher JD, Chen C, Nguyen J, Abdulla F, Nguyen P, Nguyen M, Okeley NM, Benjamin DR, Senter PD, Vercellotti GM.

PLoS One. 2015 Feb 23;10(2):e0117772. doi: 10.1371/journal.pone.0117772.


Association of coagulation activation with clinical complications in sickle cell disease.

Ataga KI, Brittain JE, Desai P, May R, Jones S, Delaney J, Strayhorn D, Hinderliter A, Key NS.

PLoS One. 2012;7(1):e29786. doi: 10.1371/journal.pone.0029786.


The HDAC inhibitors trichostatin A and suberoylanilide hydroxamic acid exhibit multiple modalities of benefit for the vascular pathobiology of sickle transgenic mice.

Hebbel RP, Vercellotti GM, Pace BS, Solovey AN, Kollander R, Abanonu CF, Nguyen J, Vineyard JV, Belcher JD, Abdulla F, Osifuye S, Eaton JW, Kelm RJ Jr, Slungaard A.

Blood. 2010 Mar 25;115(12):2483-90. doi: 10.1182/blood-2009-02-204990.


Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytes.

Shet AS, Aras O, Gupta K, Hass MJ, Rausch DJ, Saba N, Koopmeiners L, Key NS, Hebbel RP.

Blood. 2003 Oct 1;102(7):2678-83.


Tissue factor haploinsufficiency during endotoxin induced coagulation and inflammation in mice.

Schoenmakers SH, Versteeg HH, Groot AP, Reitsma PH, Spek CA.

J Thromb Haemost. 2004 Dec;2(12):2185-93.


Tissue factor-positive monocytes in children with sickle cell disease: correlation with biomarkers of haemolysis.

Setty BN, Key NS, Rao AK, Gayen-Betal S, Krishnan S, Dampier CD, Stuart MJ.

Br J Haematol. 2012 May;157(3):370-80. doi: 10.1111/j.1365-2141.2012.09065.x.


A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction.

Hoppe C, Kuypers F, Larkin S, Hagar W, Vichinsky E, Styles L.

Br J Haematol. 2011 Jun;153(5):655-63. doi: 10.1111/j.1365-2141.2010.08480.x.


Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.

Luyendyk JP, Flanagan KC, Williams CD, Jaeschke H, Slusser JG, Mackman N, Cantor GH.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):256-62. doi: 10.1016/j.taap.2010.11.002.


Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.

Pawlinski R, Pedersen B, Schabbauer G, Tencati M, Holscher T, Boisvert W, Andrade-Gordon P, Frank RD, Mackman N.

Blood. 2004 Feb 15;103(4):1342-7.


Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients.

Sakamoto TM, Lanaro C, Ozelo MC, Garrido VT, Olalla-Saad ST, Conran N, Costa FF.

Microvasc Res. 2013 Nov;90:173-9. doi: 10.1016/j.mvr.2013.10.002.


Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis.

Nur E, van Beers EJ, Martina S, Cuccovillo I, Otten HM, Schnog JJ, Meijers JC, Mantovani A, Brandjes DP, Bottazzi B, Biemond BJ; CURAMA Study Group..

Blood Cells Mol Dis. 2011 Mar 15;46(3):189-94. doi: 10.1016/j.bcmd.2010.10.016.


Supplemental Content

Support Center