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Items: 1 to 20 of 80

1.

A colony-forming assay for determining the establishment efficiency of S/MAR-containing nonviral episomal expression vectors.

Hagedorn C, Baiker A, Postberg J, Ehrhardt A, Lipps HJ.

Cold Spring Harb Protoc. 2012 Jun 1;2012(6):706-8. doi: 10.1101/pdb.prot069500.

PMID:
22661431
2.

Handling S/MAR vectors.

Hagedorn C, Baiker A, Postberg J, Ehrhardt A, Lipps HJ.

Cold Spring Harb Protoc. 2012 Jun 1;2012(6):657-63. doi: 10.1101/pdb.top068262.

PMID:
22661441
3.

Rescue of S/MAR-containing nonviral episomal expression vectors.

Hagedorn C, Baiker A, Postberg J, Ehrhardt A, Lipps HJ.

Cold Spring Harb Protoc. 2012 Jun 1;2012(6):709-11. doi: 10.1101/pdb.prot069518.

PMID:
22661432
4.

Minicircle performance depending on S/MAR-nuclear matrix interactions.

Broll S, Oumard A, Hahn K, Schambach A, Bode J.

J Mol Biol. 2010 Feb 5;395(5):950-65. doi: 10.1016/j.jmb.2009.11.066. Epub 2009 Dec 29.

PMID:
20004666
5.

The functional role of S/MARs in episomal vectors as defined by the stress-induced destabilization profile of the vector sequences.

Giannakopoulos A, Stavrou EF, Zarkadis I, Zoumbos N, Thrasher AJ, Athanassiadou A.

J Mol Biol. 2009 Apr 17;387(5):1239-49. doi: 10.1016/j.jmb.2009.02.043. Epub 2009 Feb 25.

PMID:
19248788
6.

Nuclear scaffold/matrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome.

Jenke AC, Stehle IM, Herrmann F, Eisenberger T, Baiker A, Bode J, Fackelmayer FO, Lipps HJ.

Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11322-7. Epub 2004 Jul 22.

7.

Scaffold/matrix attached region-based nonviral episomal vectors.

Hagedorn C, Wong SP, Harbottle R, Lipps HJ.

Hum Gene Ther. 2011 Aug;22(8):915-23. doi: 10.1089/hum.2011.084. Epub 2011 Jul 27.

PMID:
21644838
8.
9.

Physiological levels of HBB transgene expression from S/MAR element-based replicating episomal vectors.

Sgourou A, Routledge S, Spathas D, Athanassiadou A, Antoniou MN.

J Biotechnol. 2009 Aug 20;143(2):85-94. doi: 10.1016/j.jbiotec.2009.06.018. Epub 2009 Jun 25.

PMID:
19559736
10.
11.

Establishment and mitotic stability of an extra-chromosomal mammalian replicon.

Stehle IM, Postberg J, Rupprecht S, Cremer T, Jackson DA, Lipps HJ.

BMC Cell Biol. 2007 Aug 6;8:33.

12.

A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells.

Piechaczek C, Fetzer C, Baiker A, Bode J, Lipps HJ.

Nucleic Acids Res. 1999 Jan 15;27(2):426-8.

13.

Exploiting a minimal system to study the epigenetic control of DNA replication: the interplay between transcription and replication.

Stehle IM, Scinteie MF, Baiker A, Jenke AC, Lipps HJ.

Chromosome Res. 2003;11(5):413-21.

PMID:
12971718
14.

Efficient recombinant production in mammalian cells using a novel IR/MAR gene amplification method.

Araki Y, Hamafuji T, Noguchi C, Shimizu N.

PLoS One. 2012;7(7):e41787. doi: 10.1371/journal.pone.0041787. Epub 2012 Jul 23.

15.

[Effect of Intron Orientation on the Expression of Transgene Imposed by MAR Expression Vector in Stably Recombinant CHO Cells].

Li Q, Zhao CP, Wang XY, Sun QL, Wang TY.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2016 Mar;47(2):189-91, 243. Chinese.

PMID:
27263292
17.

Mitotic stability of an episomal vector containing a human scaffold/matrix-attached region is provided by association with nuclear matrix.

Baiker A, Maercker C, Piechaczek C, Schmidt SB, Bode J, Benham C, Lipps HJ.

Nat Cell Biol. 2000 Mar;2(3):182-4. No abstract available.

PMID:
10707091
18.

Modified S/MAR episomal vectors for stably expressing fluorescent protein-tagged transgenes with small cell-to-cell fluctuations.

Mizutani A, Kikkawa E, Matsuno A, Shigenari A, Okinaga H, Murakami M, Ishida H, Tanaka M, Inoko H.

Anal Biochem. 2013 Dec 1;443(1):113-6. doi: 10.1016/j.ab.2013.08.009. Epub 2013 Aug 19.

PMID:
23969013
19.

Non-viral S/MAR vectors replicate episomally in vivo when provided with a selective advantage.

Wong SP, Argyros O, Coutelle C, Harbottle RP.

Gene Ther. 2011 Jan;18(1):82-7. doi: 10.1038/gt.2010.116. Epub 2010 Aug 26.

PMID:
20739959
20.

MAR characteristic motifs mediate episomal vector in CHO cells.

Lin Y, Li Z, Wang T, Wang X, Wang L, Dong W, Jing C, Yang X.

Gene. 2015 Apr 1;559(2):137-43. doi: 10.1016/j.gene.2015.01.032. Epub 2015 Jan 15.

PMID:
25598284

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