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Items: 1 to 20 of 86

1.

Strategies for discovery of small molecule radiation protectors and radiation mitigators.

Greenberger JS, Clump D, Kagan V, Bayir H, Lazo JS, Wipf P, Li S, Gao X, Epperly MW.

Front Oncol. 2012 Jan 13;1:59. doi: 10.3389/fonc.2011.00059. eCollection 2011.

2.

Two strategies for the development of mitochondrion-targeted small molecule radiation damage mitigators.

Rwigema JC, Beck B, Wang W, Doemling A, Epperly MW, Shields D, Goff JP, Franicola D, Dixon T, Frantz MC, Wipf P, Tyurina Y, Kagan VE, Wang H, Greenberger JS.

Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):860-8. doi: 10.1016/j.ijrobp.2011.01.059. Epub 2011 Apr 13.

3.

Can Radiosensitivity Associated with Defects in DNA Repair be Overcome by Mitochondrial-Targeted Antioxidant Radioprotectors.

Greenberger JS, Berhane H, Shinde A, Rhieu BH, Bernard M, Wipf P, Skoda EM, Epperly MW.

Front Oncol. 2014 Feb 17;4:24. doi: 10.3389/fonc.2014.00024. eCollection 2014.

4.

Normal tissue protection for improving radiotherapy: Where are the Gaps?

Prasanna PG, Stone HB, Wong RS, Capala J, Bernhard EJ, Vikram B, Coleman CN.

Transl Cancer Res. 2012 Jun;1(1):35-48.

5.

Antioxidant Approaches to Management of Ionizing Irradiation Injury.

Greenberger J, Kagan V, Bayir H, Wipf P, Epperly M.

Antioxidants (Basel). 2015 Jan 23;4(1):82-101. doi: 10.3390/antiox4010082.

6.

Effectiveness of Analogs of the GS-Nitroxide, JP4-039, as Total Body Irradiation Mitigators.

Epperly MW, Sacher JR, Krainz T, Zhang X, Wipf P, Liang M, Fisher R, Li S, Wang H, Greenberger JS.

In Vivo. 2017 Jan 2;31(1):39-43.

7.

Screening of antimicrobial agents for in vitro radiation protection and mitigation capacity, including those used in supportive care regimens for bone marrow transplant recipients.

Epperly MW, Franicola D, Shields D, Rwigema JC, Stone B, Zhang X, McBride W, Georges G, Wipf P, Greenberger JS.

In Vivo. 2010 Jan-Feb;24(1):9-19.

8.

New approaches to radiation protection.

Rosen EM, Day R, Singh VK.

Front Oncol. 2015 Jan 20;4:381. doi: 10.3389/fonc.2014.00381. eCollection 2014. Review.

9.

Radiosensitizers, radioprotectors, and radiation mitigators.

Raviraj J, Bokkasam VK, Kumar VS, Reddy US, Suman V.

Indian J Dent Res. 2014 Jan-Feb;25(1):83-90. doi: 10.4103/0970-9290.131142. Review.

10.

High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones.

Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH.

Clin Cancer Res. 2009 Dec 1;15(23):7238-45. doi: 10.1158/1078-0432.CCR-09-1964. Epub 2009 Nov 17.

11.

Identification of druggable targets for radiation mitigation using a small interfering RNA screening assay.

Zellefrow CD, Sharlow ER, Epperly MW, Reese CE, Shun T, Lira A, Greenberger JS, Lazo JS.

Radiat Res. 2012 Sep;178(3):150-9. Epub 2012 Jul 2.

12.

Identification of nitroxide radioprotectors.

Hahn SM, Wilson L, Krishna CM, Liebmann J, DeGraff W, Gamson J, Samuni A, Venzon D, Mitchell JB.

Radiat Res. 1992 Oct;132(1):87-93.

PMID:
1410280
13.

A new class of molecular targeted radioprotectors: GSK-3beta inhibitors.

Thotala DK, Geng L, Dickey AK, Hallahan DE, Yazlovitskaya EM.

Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):557-65. doi: 10.1016/j.ijrobp.2009.09.024.

14.

High throughput screening of small molecule libraries for modifiers of radiation responses.

Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH.

Int J Radiat Biol. 2011 Aug;87(8):839-45. doi: 10.3109/09553002.2011.560994. Epub 2011 Mar 14.

15.

The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair.

Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS.

In Vivo. 2009 Sep-Oct;23(5):717-26.

16.

Ionizing irradiation protection and mitigation of murine cells by carbamazepine is p53 and autophagy independent.

Kim H, Bernard ME, Farkas A, Goff J, Kalash R, Houghton F, Shields D, Franicola D, Dixon T, Zhang X, Epperly M, Wang H, Cobanoglu MC, Greenberger JS.

In Vivo. 2012 May-Jun;26(3):341-54.

17.

Radioprotectors and mitigators of radiation-induced normal tissue injury.

Citrin D, Cotrim AP, Hyodo F, Baum BJ, Krishna MC, Mitchell JB.

Oncologist. 2010;15(4):360-71. doi: 10.1634/theoncologist.2009-S104. Review.

18.

Glycogen synthase kinase 3β inhibitors protect hippocampal neurons from radiation-induced apoptosis by regulating MDM2-p53 pathway.

Thotala DK, Hallahan DE, Yazlovitskaya EM.

Cell Death Differ. 2012 Mar;19(3):387-96. doi: 10.1038/cdd.2011.94. Epub 2011 Jul 8.

19.
20.

Small molecule GS-nitroxide ameliorates ionizing irradiation-induced delay in bone wound healing in a novel murine model.

Gokhale A, Rwigema JC, Epperly MW, Glowacki J, Wang H, Wipf P, Goff JP, Dixon T, Patrene K, Greenberger JS.

In Vivo. 2010 Jul-Aug;24(4):377-85.

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