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Items: 1 to 20 of 60

1.

Modulating telomerase activity in tumor patients by targeting dyskerin binding site for hTR.

Katunaric M, Zamolo G.

Med Hypotheses. 2012 Sep;79(3):319-20. doi: 10.1016/j.mehy.2012.05.021. Epub 2012 May 30.

PMID:
22652042
2.

Multiscale in situ analysis of the role of dyskerin in lung cancer cells.

Fernandez-Garcia I, Marcos T, Muñoz-Barrutia A, Serrano D, Pio R, Montuenga LM, Ortiz-de-Solorzano C.

Integr Biol (Camb). 2013 Feb;5(2):402-13. doi: 10.1039/c2ib20219k.

PMID:
23233094
3.

Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations.

Ashbridge B, Orte A, Yeoman JA, Kirwan M, Vulliamy T, Dokal I, Klenerman D, Balasubramanian S.

Biochemistry. 2009 Nov 24;48(46):10858-65. doi: 10.1021/bi901373e.

5.

Differential regulation of MRN (Mre11-Rad50-Nbs1) complex subunits and telomerase activity in cancer cells.

Kavitha CV, Choudhary B, Raghavan SC, Muniyappa K.

Biochem Biophys Res Commun. 2010 Sep 3;399(4):575-80. doi: 10.1016/j.bbrc.2010.07.117. Epub 2010 Aug 2.

PMID:
20682289
6.

Native gel electrophoresis of human telomerase distinguishes active complexes with or without dyskerin.

Gardano L, Holland L, Oulton R, Le Bihan T, Harrington L.

Nucleic Acids Res. 2012 Mar;40(5):e36. doi: 10.1093/nar/gkr1243. Epub 2011 Dec 19.

7.

A telomerase component is defective in the human disease dyskeratosis congenita.

Mitchell JR, Wood E, Collins K.

Nature. 1999 Dec 2;402(6761):551-5.

PMID:
10591218
8.

Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer.

Montanaro L, Brigotti M, Clohessy J, Barbieri S, Ceccarelli C, Santini D, Taffurelli M, Calienni M, Teruya-Feldstein J, Trerè D, Pandolfi PP, Derenzini M.

J Pathol. 2006 Sep;210(1):10-8.

PMID:
16841302
9.

Inhibition of telomerase RNA decay rescues telomerase deficiency caused by dyskerin or PARN defects.

Shukla S, Schmidt JC, Goldfarb KC, Cech TR, Parker R.

Nat Struct Mol Biol. 2016 Apr;23(4):286-92. doi: 10.1038/nsmb.3184. Epub 2016 Mar 7.

10.

Dyskeratosis congenita: its link to telomerase and aplastic anaemia.

Dokal I, Vulliamy T.

Blood Rev. 2003 Dec;17(4):217-25. Review.

PMID:
14556776
11.

Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation.

Cerone MA, Ward RJ, Londoño-Vallejo JA, Autexier C.

Cell Cycle. 2005 Apr;4(4):585-9. Epub 2005 Apr 3.

PMID:
15753647
12.

Relationship between dyskerin expression and telomerase activity in human breast cancer.

Montanaro L, Calienni M, Ceccarelli C, Santini D, Taffurelli M, Pileri S, Treré D, Derenzini M.

Cell Oncol. 2008;30(6):483-90.

13.

[siRNA targeting telomerase--effective tool in anti-cancer therapy?].

Rubiś B, Półrolniczak A, Rybczyńska M.

Postepy Biochem. 2008;54(4):384-92. Review. Polish.

PMID:
19248585
14.

Correlation of dyskerin expression with active proliferation independent of telomerase.

Alawi F, Lin P, Ziober B, Patel R.

Head Neck. 2011 Jul;33(7):1041-51. doi: 10.1002/hed.21579. Epub 2010 Dec 8.

15.

Mammalian telomeres and telomerase: why they matter for cancer and aging.

Blasco MA.

Eur J Cell Biol. 2003 Sep;82(9):441-6. Review.

PMID:
14582532
16.

Dyskeratosis congenita mutations in the H/ACA domain of human telomerase RNA affect its assembly into a pre-RNP.

Trahan C, Dragon F.

RNA. 2009 Feb;15(2):235-43. doi: 10.1261/rna.1354009. Epub 2008 Dec 17.

17.

Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance.

Kannan K, Nelson AD, Shippen DE.

Mol Cell Biol. 2008 Apr;28(7):2332-41. doi: 10.1128/MCB.01490-07. Epub 2008 Jan 22.

18.
19.

DKC1 overexpression associated with prostate cancer progression.

Sieron P, Hader C, Hatina J, Engers R, Wlazlinski A, Müller M, Schulz WA.

Br J Cancer. 2009 Oct 20;101(8):1410-6. doi: 10.1038/sj.bjc.6605299. Epub 2009 Sep 15.

20.

MYC-Driven Neuroblastomas Are Addicted to a Telomerase-Independent Function of Dyskerin.

O'Brien R, Tran SL, Maritz MF, Liu B, Kong CF, Purgato S, Yang C, Murray J, Russell AJ, Flemming CL, von Jonquieres G, Pickett HA, London WB, Haber M, Gunaratne PH, Norris MD, Perini G, Fletcher JI, MacKenzie KL.

Cancer Res. 2016 Jun 15;76(12):3604-17. doi: 10.1158/0008-5472.CAN-15-0879. Epub 2016 Apr 13.

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