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Alcohol use predicts ER visits in individuals with alpha-1 antitrypsin deficiency (AATD) associated COPD.

Hoth KF, Ford DW, Sandhaus RA, Strange C, Wamboldt FS, Holm KE.

COPD. 2012 Aug;9(4):417-25. doi: 10.3109/15412555.2012.684414. Epub 2012 May 31.


Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD.

Holm KE, Borson S, Sandhaus RA, Ford DW, Strange C, Bowler RP, Make BJ, Wamboldt FS.

COPD. 2013 Apr;10(2):226-34. doi: 10.3109/15412555.2012.719049.


The impact of smoke exposure on the clinical phenotype of alpha-1 antitrypsin deficiency in Ireland: exploiting a national registry to understand a rare disease.

O'Brien ME, Pennycooke K, Carroll TP, Shum J, Fee LT, O'Connor C, Logan PM, Reeves EP, McElvaney NG.

COPD. 2015 May;12 Suppl 1:2-9. doi: 10.3109/15412555.2015.1021913.


The impact of SHS exposure on health status and exacerbations among patients with COPD.

Eisner MD, Iribarren C, Yelin EH, Sidney S, Katz PP, Sanchez G, Blanc PD.

Int J Chron Obstruct Pulmon Dis. 2009;4:169-76. Epub 2009 May 7.


The association between alcohol consumption and risk of COPD exacerbation in a veteran population.

Greene CC, Bradley KA, Bryson CL, Blough DK, Evans LE, Udris EM, Au DH.

Chest. 2008 Oct;134(4):761-7. doi: 10.1378/chest.07-3081. Epub 2008 Jul 14.


Randomized trial of pragmatic education for low-risk COPD patients: impact on hospitalizations and emergency department visits.

Siddique HH, Olson RH, Parenti CM, Rector TS, Caldwell M, Dewan NA, Rice KL.

Int J Chron Obstruct Pulmon Dis. 2012;7:719-28. doi: 10.2147/COPD.S36025. Epub 2012 Oct 25.


PiSZ alpha-1 antitrypsin deficiency (AATD): pulmonary phenotype and prognosis relative to PiZZ AATD and PiMM COPD.

Green CE, Vayalapra S, Hampson JA, Mukherjee D, Stockley RA, Turner AM.

Thorax. 2015 Oct;70(10):939-45. doi: 10.1136/thoraxjnl-2015-206906. Epub 2015 Jul 3.


Characteristics of Alpha-1 Antitrypsin-Deficient Individuals in the Long-term Oxygen Treatment Trial and Comparison with Other Subjects with Chronic Obstructive Pulmonary Disease.

Stoller JK, Aboussouan LS, Kanner RE, Wilson LA, Diaz P, Wise R; LOTT Research Group.

Ann Am Thorac Soc. 2015 Dec;12(12):1796-804. doi: 10.1513/AnnalsATS.201506-389OC.


Clinical characteristics of subjects with symptoms of alpha1-antitrypsin deficiency older than 60 years.

Campos MA, Alazemi S, Zhang G, Salathe M, Wanner A, Sandhaus RA, Baier H.

Chest. 2009 Mar;135(3):600-608. doi: 10.1378/chest.08-1129. Epub 2008 Nov 18.


Utility of brief questionnaires of health-related quality of life (Airways Questionnaire 20 and Clinical COPD Questionnaire) to predict exacerbations in patients with asthma and COPD.

Blanco-Aparicio M, Vázquez I, Pita-Fernández S, Pértega-Diaz S, Verea-Hernando H.

Health Qual Life Outcomes. 2013 May 27;11:85. doi: 10.1186/1477-7525-11-85.


Sex differences in alpha-1-antitrypsin deficiency lung disease-analysis from the German registry.

Fähndrich S, Herr C, Greulich T, Seibert M, Lepper PM, Bernhard N, Lützow C, Vogelmeier C, Bals R.

COPD. 2015 May;12 Suppl 1:58-62. doi: 10.3109/15412555.2015.1023785.


Recent advances in understanding and treating COPD related to α1-antitrypsin deficiency.

Henao MP, Craig TJ.

Expert Rev Respir Med. 2016 Dec;10(12):1281-1294. Epub 2016 Nov 4. Review.


Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency.

Omachi TA, Eisner MD, Rames A, Markovtsova L, Blanc PD.

Respir Res. 2011 Mar 23;12:35. doi: 10.1186/1465-9921-12-35.


Indications for active case searches and intravenous alpha-1 antitrypsin treatment for patients with alpha-1 antitrypsin deficiency chronic pulmonary obstructive disease: an update.

Casas F, Blanco I, Martínez MT, Bustamante A, Miravitlles M, Cadenas S, Hernández JM, Lázaro L, Rodríguez E, Rodríguez-Frías F, Torres M, Lara B.

Arch Bronconeumol. 2015 Apr;51(4):185-92. doi: 10.1016/j.arbres.2014.05.008. Epub 2014 Jul 12. English, Spanish.


Is an integrative laboratory algorithm more effective in detecting alpha-1-antitrypsin deficiency in patients with premature chronic obstructive pulmonary disease than AAT concentration based screening approach?

Beletic A, Dudvarski-Ilic A, Milenkovic B, Nagorni-Obradovic L, Ljujic M, Djordjevic V, Mirkovic D, Radojkovic D, Majkic-Singh N.

Biochem Med (Zagreb). 2014;24(2):293-8. doi: 10.11613/BM.2014.032. Epub 2014 Jun 15.


Predictors of hospital admission for chronic obstructive pulmonary disease exacerbations in Canadian emergency departments.

Rowe BH, Villa-Roel C, Guttman A, Ross S, Mackey D, Sivilotti ML, Worster A, Stiell IG, Willis V, Borgundvaag B.

Acad Emerg Med. 2009 Apr;16(4):316-24. doi: 10.1111/j.1553-2712.2009.00366.x. Epub 2009 Mar 6.


Risk factors for relapse to problem drinking among current and former US military personnel: a prospective study of the Millennium Cohort.

Williams EC, Frasco MA, Jacobson IG, Maynard C, Littman AJ, Seelig AD, Crum-Cianflone NF, Nagel A, Boyko EJ.

Drug Alcohol Depend. 2015 Mar 1;148:93-101. doi: 10.1016/j.drugalcdep.2014.12.031. Epub 2015 Jan 3.


Risk factors of emergency care and admissions in COPD patients with high consumption of health resources.

Soler JJ, Sánchez L, Román P, Martínez MA, Perpiñá M.

Respir Med. 2004 Apr;98(4):318-29.


Usefulness of the CAT, LCOPD, EQ-5D and COPDSS scales in understanding the impact of lung disease in patients with alpha-1 antitrypsin deficiency.

Manca S, Rodriguez E, Huerta A, Torres M, Lazaro L, Curi S, Pirina P, Miravitlles M.

COPD. 2014 Sep;11(5):480-8. doi: 10.3109/15412555.2014.898030. Epub 2014 May 15.


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