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Items: 1 to 20 of 268

1.

Viral double-stranded RNA sensors induce antiviral, pro-inflammatory, and pro-apoptotic responses in human renal tubular epithelial cells.

Heutinck KM, Rowshani AT, Kassies J, Claessen N, van Donselaar-van der Pant KA, Bemelman FJ, Eldering E, van Lier RA, Florquin S, Ten Berge IJ, Hamann J.

Kidney Int. 2012 Sep;82(6):664-75. doi: 10.1038/ki.2012.206. Epub 2012 May 30.

2.

SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I.

Heutinck KM, Kassies J, Florquin S, ten Berge IJ, Hamann J, Rowshani AT.

Nephrol Dial Transplant. 2012 Jul;27(7):2746-54. doi: 10.1093/ndt/gfr690. Epub 2011 Dec 13.

PMID:
22167597
3.

TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea.

Park GB, Hur DY, Kim YS, Lee HK, Yang JW, Kim D.

J Cell Mol Med. 2015 May;19(5):1042-54. doi: 10.1111/jcmm.12495. Epub 2015 Mar 6.

4.

Activation of innate immune defense mechanisms contributes to polyomavirus BK-associated nephropathy.

Ribeiro A, Wörnle M, Motamedi N, Anders HJ, Gröne EF, Nitschko H, Kurktschiev P, Debiec H, Kretzler M, Cohen CD, Gröne HJ, Schlöndorff D, Schmid H.

Kidney Int. 2012 Jan;81(1):100-11. doi: 10.1038/ki.2011.311. Epub 2011 Sep 14.

5.

Innate immune response to double-stranded RNA in biliary epithelial cells is associated with the pathogenesis of biliary atresia.

Harada K, Sato Y, Itatsu K, Isse K, Ikeda H, Yasoshima M, Zen Y, Matsui A, Nakanuma Y.

Hepatology. 2007 Oct;46(4):1146-54.

PMID:
17661372
6.

Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells.

Bernardo AR, Cosgaya JM, Aranda A, Jiménez-Lara AM.

Cell Death Dis. 2013 Jan 31;4:e479. doi: 10.1038/cddis.2013.5.

7.

The C proteins of human parainfluenza virus type 1 limit double-stranded RNA accumulation that would otherwise trigger activation of MDA5 and protein kinase R.

Boonyaratanakornkit J, Bartlett E, Schomacker H, Surman S, Akira S, Bae YS, Collins P, Murphy B, Schmidt A.

J Virol. 2011 Feb;85(4):1495-506. doi: 10.1128/JVI.01297-10. Epub 2010 Dec 1.

8.

Role of double-stranded RNA pattern recognition receptors in rhinovirus-induced airway epithelial cell responses.

Wang Q, Nagarkar DR, Bowman ER, Schneider D, Gosangi B, Lei J, Zhao Y, McHenry CL, Burgens RV, Miller DJ, Sajjan U, Hershenson MB.

J Immunol. 2009 Dec 1;183(11):6989-97. doi: 10.4049/jimmunol.0901386. Epub 2009 Nov 4.

9.

Regulation and function of the cytosolic viral RNA sensor RIG-I in pancreatic beta cells.

García M, Dogusan Z, Moore F, Sato S, Hartmann G, Eizirik DL, Rasschaert J.

Biochim Biophys Acta. 2009 Nov;1793(11):1768-75. doi: 10.1016/j.bbamcr.2009.09.005. Epub 2009 Sep 10.

10.

Induction of interferon-λ contributes to TLR3 and RIG-I activation-mediated inhibition of herpes simplex virus type 2 replication in human cervical epithelial cells.

Zhou L, Li JL, Zhou Y, Liu JB, Zhuang K, Gao JF, Liu S, Sang M, Wu JG, Ho WZ.

Mol Hum Reprod. 2015 Dec;21(12):917-29. doi: 10.1093/molehr/gav058. Epub 2015 Oct 26.

11.

MDA5 and TLR3 initiate pro-inflammatory signaling pathways leading to rhinovirus-induced airways inflammation and hyperresponsiveness.

Wang Q, Miller DJ, Bowman ER, Nagarkar DR, Schneider D, Zhao Y, Linn MJ, Goldsmith AM, Bentley JK, Sajjan US, Hershenson MB.

PLoS Pathog. 2011 May;7(5):e1002070. doi: 10.1371/journal.ppat.1002070. Epub 2011 May 26.

12.

Interaction between interferon-stimulated gene 56 and melanoma differentiation-associated gene 5 in Toll-like receptor 3 signaling in normal human mesangial cells.

Imaizumi T, Aizawa-Yashiro T, Matsumiya T, Yoshida H, Watanabe S, Tsuruga K, Tatsuta T, Xing F, Hayakari R, Meng P, Tanaka H.

Am J Nephrol. 2013;37(2):118-25. doi: 10.1159/000346415. Epub 2013 Jan 29.

PMID:
23363937
13.

Melanoma differentiation-associated gene 5 regulates the expression of a chemokine CXCL10 in human mesangial cells: implications for chronic inflammatory renal diseases.

Imaizumi T, Aizawa-Yashiro T, Tsuruga K, Tanaka H, Matsumiya T, Yoshida H, Tatsuta T, Xing F, Hayakari R, Satoh K.

Tohoku J Exp Med. 2012 Sep;228(1):17-26.

14.

Rhinovirus and dsRNA induce RIG-I-like receptors and expression of interferon β and λ1 in human bronchial smooth muscle cells.

Calvén J, Yudina Y, Uller L.

PLoS One. 2013 Apr 29;8(4):e62718. doi: 10.1371/journal.pone.0062718. Print 2013.

15.

Triggering of the dsRNA sensors TLR3, MDA5, and RIG-I induces CD55 expression in synovial fibroblasts.

Karpus ON, Heutinck KM, Wijnker PJ, Tak PP, Hamann J.

PLoS One. 2012;7(5):e35606. doi: 10.1371/journal.pone.0035606. Epub 2012 May 10.

16.

Toll-like receptor 3 and RIG-I-like receptor activation induces innate antiviral responses in mouse ovarian granulosa cells.

Yan K, Zhu W, Yu L, Li N, Zhang X, Liu P, Chen Q, Chen Y, Han D.

Mol Cell Endocrinol. 2013 Jun 15;372(1-2):73-85. doi: 10.1016/j.mce.2013.03.027. Epub 2013 Apr 6.

PMID:
23567548
17.

Functional RIG-I-like receptors control the survival of mesenchymal stem cells.

Yang K, Wang J, Xiang AP, Zhan X, Wang Y, Wu M, Huang X.

Cell Death Dis. 2013 Dec 12;4:e967. doi: 10.1038/cddis.2013.504.

18.

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling.

Miyashita M, Oshiumi H, Matsumoto M, Seya T.

Mol Cell Biol. 2011 Sep;31(18):3802-19. doi: 10.1128/MCB.01368-10. Epub 2011 Jul 26.

19.

Cutting Edge: Influenza A virus activates TLR3-dependent inflammatory and RIG-I-dependent antiviral responses in human lung epithelial cells.

Le Goffic R, Pothlichet J, Vitour D, Fujita T, Meurs E, Chignard M, Si-Tahar M.

J Immunol. 2007 Mar 15;178(6):3368-72.

20.

ATP-dependent effector-like functions of RIG-I-like receptors.

Yao H, Dittmann M, Peisley A, Hoffmann HH, Gilmore RH, Schmidt T, Schmidt-Burgk J, Hornung V, Rice CM, Hur S.

Mol Cell. 2015 May 7;58(3):541-548. doi: 10.1016/j.molcel.2015.03.014. Epub 2015 Apr 16.

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