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Items: 1 to 20 of 107

1.

A nucleotide-analogue-induced gain of function corrects the error-prone nature of human DNA polymerase iota.

Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL.

J Am Chem Soc. 2012 Jun 27;134(25):10698-705. doi: 10.1021/ja304176q. Epub 2012 Jun 14.

2.

In vitro bypass of the major malondialdehyde- and base propenal-derived DNA adduct by human Y-family DNA polymerases κ, ι, and Rev1.

Maddukuri L, Eoff RL, Choi JY, Rizzo CJ, Guengerich FP, Marnett LJ.

Biochemistry. 2010 Sep 28;49(38):8415-24. doi: 10.1021/bi1009024.

3.

Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct.

Irimia A, Eoff RL, Guengerich FP, Egli M.

J Biol Chem. 2009 Aug 14;284(33):22467-80. doi: 10.1074/jbc.M109.003905. Epub 2009 Jun 19.

5.

Unique active site promotes error-free replication opposite an 8-oxo-guanine lesion by human DNA polymerase iota.

Kirouac KN, Ling H.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3210-5. doi: 10.1073/pnas.1013909108. Epub 2011 Feb 7.

6.

Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues.

Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL.

Biochemistry. 2012 Nov 13;51(45):9234-44. doi: 10.1021/bi301043k. Epub 2012 Oct 30.

7.

Translesion synthesis across 1,N6-(2-hydroxy-3-hydroxymethylpropan-1,3-diyl)-2'-deoxyadenosine (1,N6-γ-HMHP-dA) adducts by human and archebacterial DNA polymerases.

Kotapati S, Maddukuri L, Wickramaratne S, Seneviratne U, Goggin M, Pence MG, Villalta P, Guengerich FP, Marnett L, Tretyakova N.

J Biol Chem. 2012 Nov 9;287(46):38800-11. doi: 10.1074/jbc.M112.396788. Epub 2012 Sep 13.

8.

Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion.

Vasquez-Del Carpio R, Silverstein TD, Lone S, Swan MK, Choudhury JR, Johnson RE, Prakash S, Prakash L, Aggarwal AK.

PLoS One. 2009 Jun 2;4(6):e5766. doi: 10.1371/journal.pone.0005766.

9.

Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η.

Patra A, Su Y, Zhang Q, Johnson KM, Guengerich FP, Egli M.

J Biol Chem. 2016 Jul 1;291(27):14134-45. doi: 10.1074/jbc.M116.732487. Epub 2016 May 16.

PMID:
27226627
10.

Structure of human DNA polymerase iota and the mechanism of DNA synthesis.

Makarova AV, Kulbachinskiy AV.

Biochemistry (Mosc). 2012 Jun;77(6):547-61. doi: 10.1134/S0006297912060016. Review.

PMID:
22817454
11.

Replication by human DNA polymerase-iota occurs by Hoogsteen base-pairing.

Nair DT, Johnson RE, Prakash S, Prakash L, Aggarwal AK.

Nature. 2004 Jul 15;430(6997):377-80.

PMID:
15254543
12.
14.

Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV.

DeCarlo L, Gowda AS, Suo Z, Spratt TE.

Biochemistry. 2008 Aug 5;47(31):8157-64. doi: 10.1021/bi800820m. Epub 2008 Jul 11.

16.

Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η.

Patra A, Zhang Q, Guengerich FP, Egli M.

J Biol Chem. 2016 Nov 11;291(46):24304-24313. Epub 2016 Sep 30.

PMID:
27694439
17.

Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η.

Patra A, Nagy LD, Zhang Q, Su Y, Müller L, Guengerich FP, Egli M.

J Biol Chem. 2014 Jun 13;289(24):16867-82. doi: 10.1074/jbc.M114.551820. Epub 2014 Apr 23.

18.
19.

Structural and kinetic analysis of nucleoside triphosphate incorporation opposite an abasic site by human translesion DNA polymerase η.

Patra A, Zhang Q, Lei L, Su Y, Egli M, Guengerich FP.

J Biol Chem. 2015 Mar 27;290(13):8028-38. doi: 10.1074/jbc.M115.637561. Epub 2015 Feb 9.

20.

Biochemical evidence for the requirement of Hoogsteen base pairing for replication by human DNA polymerase iota.

Johnson RE, Prakash L, Prakash S.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10466-71. Epub 2005 Jul 13.

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