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Items: 1 to 20 of 209

1.

Drug discovery in pharmaceutical industry: productivity challenges and trends.

Khanna I.

Drug Discov Today. 2012 Oct;17(19-20):1088-102. doi: 10.1016/j.drudis.2012.05.007. Epub 2012 May 22. Review.

PMID:
22627006
2.

Productive university, industry, and government relationships in preclinical drug discovery and development: considerations toward a synergistic lingua franca.

Janero DR.

Expert Opin Drug Discov. 2012 Jun;7(6):449-56. doi: 10.1517/17460441.2012.685154. Epub 2012 Apr 28.

PMID:
22540843
3.

Racing to define pharmaceutical R&D external innovation models.

Wang L, Plump A, Ringel M.

Drug Discov Today. 2015 Mar;20(3):361-70. doi: 10.1016/j.drudis.2014.10.008. Epub 2014 Oct 30. Review.

PMID:
25448753
4.

Brazil: An emerging partner in drug R&D.

Rodrigues DG.

IDrugs. 2009 Aug;12(8):497-502. Review.

PMID:
19629884
5.

Mergers and innovation in the pharmaceutical industry.

Comanor WS, Scherer FM.

J Health Econ. 2013 Jan;32(1):106-13. doi: 10.1016/j.jhealeco.2012.09.006. Epub 2012 Sep 29.

PMID:
23220457
6.

An assessment of R&D productivity in the pharmaceutical industry.

Dimitri N.

Trends Pharmacol Sci. 2011 Dec;32(12):683-5. doi: 10.1016/j.tips.2011.09.005. Epub 2011 Oct 24.

PMID:
22030299
7.

How to improve R&D productivity: the pharmaceutical industry's grand challenge.

Paul SM, Mytelka DS, Dunwiddie CT, Persinger CC, Munos BH, Lindborg SR, Schacht AL.

Nat Rev Drug Discov. 2010 Mar;9(3):203-14. doi: 10.1038/nrd3078. Epub 2010 Feb 19. Review.

PMID:
20168317
8.
9.

Can open-source drug R&D repower pharmaceutical innovation?

Munos B.

Clin Pharmacol Ther. 2010 May;87(5):534-6. doi: 10.1038/clpt.2010.26. Review.

PMID:
20407458
10.

China: current trends in pharmaceutical drug discovery.

Luo Y.

IDrugs. 2008 Apr;11(4):279-82.

PMID:
18379963
11.

Is poor research the cause of the declining productivity of the pharmaceutical industry? An industry in need of a paradigm shift.

Sams-Dodd F.

Drug Discov Today. 2013 Mar;18(5-6):211-7. doi: 10.1016/j.drudis.2012.10.010. Epub 2012 Nov 3.

PMID:
23131208
12.

Overcoming the obstacles in the pharma/biotech industry: 2009 update.

Graul AI, Revel L, Tell M, Rosa E, Cruces E.

Drug News Perspect. 2010 Jan-Feb;23(1):48-63. doi: 10.1358/dnp.2010.23.1.1437302. Review.

PMID:
20155219
13.

The value of drug repositioning in the current pharmaceutical market.

Tobinick EL.

Drug News Perspect. 2009 Mar;22(2):119-25. doi: 10.1358/dnp.2009.22.2.1303818. Review.

PMID:
19330170
14.

Open-access public-private partnerships to enable drug discovery--new approaches.

Müller S, Weigelt J.

IDrugs. 2010 Mar;13(3):175-80. Review.

PMID:
20191434
15.

Drug discovery: new models for industry-academic partnerships.

Tralau-Stewart CJ, Wyatt CA, Kleyn DE, Ayad A.

Drug Discov Today. 2009 Jan;14(1-2):95-101. doi: 10.1016/j.drudis.2008.10.003. Epub 2008 Nov 21. Review.

PMID:
18992364
16.

Innovative antibacterial drugs: nothing ventured, nothing gained.

Stein J.

Expert Opin Investig Drugs. 2005 Feb;14(2):107-9.

PMID:
15757389
17.

Outsourcing drug discovery to India and China: from surviving to thriving.

Subramaniam S, Dugar S.

Drug Discov Today. 2012 Oct;17(19-20):1055-8. doi: 10.1016/j.drudis.2012.04.005. Epub 2012 Apr 19.

PMID:
22542471
18.

Medications development for substance-use disorders: contextual influences (dis)incentivizing pharmaceutical-industry positioning.

Janero DR.

Expert Opin Drug Discov. 2014 Nov;9(11):1265-79. doi: 10.1517/17460441.2014.951631. Epub 2014 Aug 27. Review.

PMID:
25162124
19.

Quality by design in lead optimization: a new strategy to address productivity in drug discovery.

Rossi T, Braggio S.

Curr Opin Pharmacol. 2011 Oct;11(5):515-20. doi: 10.1016/j.coph.2011.05.004. Epub 2011 Jun 7. Review.

PMID:
21652263
20.

How should we support pharmaceutical innovation?

Grootendorst P.

Expert Rev Pharmacoecon Outcomes Res. 2009 Aug;9(4):313-20. doi: 10.1586/erp.09.34.

PMID:
19670991

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