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Items: 1 to 20 of 126

1.

Improved input parameters for diffusion models of skin absorption.

Hansen S, Lehr CM, Schaefer UF.

Adv Drug Deliv Rev. 2013 Feb;65(2):251-64. doi: 10.1016/j.addr.2012.04.011. Epub 2012 May 22. Review.

PMID:
22626979
2.

In-silico model of skin penetration based on experimentally determined input parameters. Part II: mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters.

Naegel A, Hansen S, Neumann D, Lehr CM, Schaefer UF, Wittum G, Heisig M.

Eur J Pharm Biopharm. 2008 Feb;68(2):368-79. Epub 2007 Jun 15. Erratum in: Eur J Pharm Biopharm. 2008 Mar;68(3):846.

PMID:
17766097
3.

In-silico model of skin penetration based on experimentally determined input parameters. Part I: experimental determination of partition and diffusion coefficients.

Hansen S, Henning A, Naegel A, Heisig M, Wittum G, Neumann D, Kostka KH, Zbytovska J, Lehr CM, Schaefer UF.

Eur J Pharm Biopharm. 2008 Feb;68(2):352-67. Epub 2007 May 29.

PMID:
17587558
4.

Computational modeling of the skin barrier.

Naegel A, Heisig M, Wittum G.

Methods Mol Biol. 2011;763:1-32. doi: 10.1007/978-1-61779-191-8_1.

PMID:
21874441
5.

Design and performance of a spreadsheet-based model for estimating bioavailability of chemicals from dermal exposure.

Dancik Y, Miller MA, Jaworska J, Kasting GB.

Adv Drug Deliv Rev. 2013 Feb;65(2):221-36. doi: 10.1016/j.addr.2012.01.006. Epub 2012 Jan 23. Review.

PMID:
22285584
6.

A network model of successive partitioning-limited solute diffusion through the stratum corneum.

Schumm P, Scoglio CM, van der Merwe D.

J Theor Biol. 2010 Feb 7;262(3):471-7. doi: 10.1016/j.jtbi.2009.10.016. Epub 2009 Oct 13.

PMID:
19833138
7.

Heterogeneity effects on permeability-partition coefficient relationships in human stratum corneum.

Anderson BD, Higuchi WI, Raykar PV.

Pharm Res. 1988 Sep;5(9):566-73.

PMID:
3247319
8.

The role of corneocytes in skin transport revised--a combined computational and experimental approach.

Hansen S, Naegel A, Heisig M, Wittum G, Neumann D, Kostka KH, Meiers P, Lehr CM, Schaefer UF.

Pharm Res. 2009 Jun;26(6):1379-97. doi: 10.1007/s11095-009-9849-7. Epub 2009 Feb 25.

PMID:
19240984
9.

Modeling of diffusion with partitioning in stratum corneum using a finite element model.

Barbero AM, Frasch HF.

Ann Biomed Eng. 2005 Sep;33(9):1281-92.

PMID:
16133933
10.

An extended database of keratin binding.

Hansen S, Selzer D, Schaefer UF, Kasting GB.

J Pharm Sci. 2011 May;100(5):1712-26. doi: 10.1002/jps.22396. Epub 2010 Nov 30.

PMID:
21374609
11.

Improved method for determining partition and diffusion coefficients in human dermis.

Ibrahim R, Kasting GB.

J Pharm Sci. 2010 Dec;99(12):4928-39. doi: 10.1002/jps.22216.

PMID:
20533434
13.

In vitro human topical bioactive drug transdermal absorption: estradiol.

Xing MM, Hui X, Zhong W, Pan N, Yaghmaie F, Maibach HI.

Cutan Ocul Toxicol. 2009;28(4):171-5. doi: 10.3109/15569520903097622.

PMID:
19888886
14.

Transcellular route of diffusion through stratum corneum: results from finite element models.

Barbero AM, Frasch HF.

J Pharm Sci. 2006 Oct;95(10):2186-94.

PMID:
16883560
15.

Mathematical models to describe iontophoretic transport in vitro and in vivo and the effect of current application on the skin barrier.

Gratieri T, Kalia YN.

Adv Drug Deliv Rev. 2013 Feb;65(2):315-29. doi: 10.1016/j.addr.2012.04.012. Epub 2012 May 22. Review.

PMID:
22626977
16.

Estimation of maximum transdermal flux of nonionized xenobiotics from basic physicochemical determinants.

Milewski M, Stinchcomb AL.

Mol Pharm. 2012 Jul 2;9(7):2111-20. doi: 10.1021/mp300146m. Epub 2012 Jun 15.

17.

Predicting the dermal absorption of thalidomide and its derivatives.

Hadgraft J, Goosen C, du Plessis J, Flynn G.

Skin Pharmacol Appl Skin Physiol. 2003 Mar-Apr;16(2):123-9.

PMID:
12637788
18.

A physiologically based pharmacokinetic model of organophosphate dermal absorption.

van der Merwe D, Brooks JD, Gehring R, Baynes RE, Monteiro-Riviere NA, Riviere JE.

Toxicol Sci. 2006 Jan;89(1):188-204. Epub 2005 Oct 12.

19.

Effect of therapeutic ultrasound on partition and diffusion coefficients in human stratum corneum.

Mitragotri S.

J Control Release. 2001 Mar 12;71(1):23-9. Review.

PMID:
11245905
20.
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