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Items: 1 to 20 of 89

1.

Cytotoxicity of semisynthetic acetal triterpenes from one-pot vicinal diol cleavage following by lactolization: reaction promoted by NaIO4/SiO2 gel in THF.

Sandjo LP, Djoumessi AV, Rincheval V, Poumale HM, Abegaz BM, Ngadjui BT.

Nat Prod Res. 2013 Apr;27(8):711-8. doi: 10.1080/14786419.2012.691494. Epub 2012 May 23.

PMID:
22616577
2.

Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity.

Santos RC, Salvador JA, Marín S, Cascante M.

Bioorg Med Chem. 2009 Sep 1;17(17):6241-50. doi: 10.1016/j.bmc.2009.07.050. Epub 2009 Jul 25.

PMID:
19674909
3.

[Epimerization of hydroxyl group in the lupan series of triterpenes].

Symon AV, Kaplun AP, Vlasenkova NK, Gerasimova GK, Shon le B, Litvin EF, Kozlova LM, Surkova EL, Shvets VI.

Bioorg Khim. 2003 Mar-Apr;29(2):208-13. Russian.

PMID:
12708322
4.

Synthesis, cytotoxicity and liposome preparation of 28-acetylenic betulin derivatives.

Csuk R, Barthel A, Kluge R, Ströhl D.

Bioorg Med Chem. 2010 Oct 15;18(20):7252-9. doi: 10.1016/j.bmc.2010.08.023. Epub 2010 Aug 26.

PMID:
20846866
5.

Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives.

Liu Q, Liu H, Zhang L, Guo T, Wang P, Geng M, Li Y.

Eur J Med Chem. 2013 Jun;64:1-15. doi: 10.1016/j.ejmech.2013.04.016. Epub 2013 Apr 15.

PMID:
23639650
6.

Synthesis, characterization and cytotoxicity of new rotundic acid derivatives.

He YF, Nan ML, Sun JM, Meng ZJ, Yue FG, Zhao QC, Yang XH, Wang H.

Molecules. 2012 Jan 31;17(2):1278-91. doi: 10.3390/molecules17021278.

7.

Hemisynthetic secofriedelane triterpenes with inhibitory activity against the growth of human tumor cell lines in vitro.

Moiteiro C, Manta C, Justino F, Tavares R, Curto MJ, Pedro M, Nascimento MS, Pinto M.

J Nat Prod. 2004 Jul;67(7):1193-6.

PMID:
15270581
8.

Synthesis of betulinic acid derivatives with activity against human melanoma.

Kim DS, Pezzuto JM, Pisha E.

Bioorg Med Chem Lett. 1998 Jul 7;8(13):1707-12.

PMID:
9873420
9.

Design, synthesis and cytotoxicity of cell death mechanism of rotundic acid derivatives.

He YF, Nan ML, Sun JM, Meng ZJ, Li W, Zhang M.

Bioorg Med Chem Lett. 2013 May 1;23(9):2543-7. doi: 10.1016/j.bmcl.2013.03.005. Epub 2013 Mar 13.

PMID:
23558236
10.

Synthesis, encapsulation and antitumor activity of new betulin derivatives.

Csuk R, Barthel A, Sczepek R, Siewert B, Schwarz S.

Arch Pharm (Weinheim). 2011 Jan;344(1):37-49. doi: 10.1002/ardp.201000232. Epub 2010 Dec 16.

PMID:
21213350
11.

[Synthesis and cytotoxicity of triterpenoid seven members cyclic amines].

Kazakova OB, Giniiatullina GV, Medvedeva NI, Lopatina TV, Baĭkova IP, Tolstikov GA, Apryshko GN.

Bioorg Khim. 2014 Mar-Apr;40(2):217-25. Russian.

PMID:
25895342
12.

Glycosidation of lupane-type triterpenoids as potent in vitro cytotoxic agents.

Gauthier C, Legault J, Lebrun M, Dufour P, Pichette A.

Bioorg Med Chem. 2006 Oct 1;14(19):6713-25. Epub 2006 Jun 19.

PMID:
16787747
13.

Synthesis of an antitumor active endoperoxide from 11-keto-beta-boswellic acid.

Csuk R, Niesen-Barthel A, Barthel A, Kluge R, Ströhl D.

Eur J Med Chem. 2010 Sep;45(9):3840-3. doi: 10.1016/j.ejmech.2010.05.036. Epub 2010 May 24.

PMID:
20538386
14.

[Synthesis and antitumor activity of cyclopropane derivatives of betulinic and betulonic acids].

Symon AV, Veselova NN, Kaplun AP, Vlasenkova NK, Fedorova GA, Liutik AI, Gerasimova GK, Shvrts VI.

Bioorg Khim. 2005 May-Jun;31(3):320-5. Russian.

PMID:
16004391
15.

[The synthesis of triterpenic amides based on 2,3-seco-1-cyano-19beta,28-epoxy-18alpha-olean-3-oic acid].

Tolmacheva IA, Igosheva EV, Grishko VV, Zhukova OS, Gerasimova GK.

Bioorg Khim. 2010 May-Jun;36(3):410-5. Russian.

PMID:
20644597
16.

Novel rotundic acid derivatives: synthesis, structural characterization and in vitro antitumor activity.

Chen Y, He YF, Nan ML, Sun WY, Hu J, Cui A, Li F, Wang F.

Int J Mol Med. 2013 Feb;31(2):353-60. doi: 10.3892/ijmm.2012.1206. Epub 2012 Dec 6.

PMID:
23233042
17.

New lupane derived compounds with pro-apoptotic activity in cancer cells: synthesis and structure-activity relationships.

Sarek J, Klinot J, Dzubák P, Klinotová E, Nosková V, Krecek V, Korínková G, Thomson JO, Janost'áková A, Wang S, Parsons S, Fischer PM, Zhelev NZ, Hajdúch M.

J Med Chem. 2003 Dec 4;46(25):5402-15.

PMID:
14640549
18.

Correlation of cytotoxic activity of betulinines and their hydroxy analogues.

Sarek J, Kvasnica M, Urban M, Klinot J, Hajduch M.

Bioorg Med Chem Lett. 2005 Oct 1;15(19):4196-200.

PMID:
16051489
19.

In vitro anticancer studies of alpha- and beta-D-glucopyranose betulin anomers.

Kommera H, Kaluderović GN, Bette M, Kalbitz J, Fuchs P, Fulda S, Mier W, Paschke R.

Chem Biol Interact. 2010 Apr 29;185(2):128-36. doi: 10.1016/j.cbi.2010.02.038. Epub 2010 Mar 1.

PMID:
20193672
20.

Synthesis and cytotoxicity of novel ursolic acid derivatives containing an acyl piperazine moiety.

Liu MC, Yang SJ, Jin LH, Hu DY, Xue W, Song BA, Yang S.

Eur J Med Chem. 2012 Dec;58:128-35. doi: 10.1016/j.ejmech.2012.08.048. Epub 2012 Oct 6.

PMID:
23124210

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