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Items: 1 to 20 of 171

1.

TGF-β autocrine pathway and MAPK signaling promote cell invasiveness and in vivo mammary adenocarcinoma tumor progression.

Daroqui MC, Vazquez P, Bal de Kier Joffé E, Bakin AV, Puricelli LI.

Oncol Rep. 2012 Aug;28(2):567-75. doi: 10.3892/or.2012.1813.

2.

Transforming growth factor-beta signaling-deficient fibroblasts enhance hepatocyte growth factor signaling in mammary carcinoma cells to promote scattering and invasion.

Cheng N, Chytil A, Shyr Y, Joly A, Moses HL.

Mol Cancer Res. 2008 Oct;6(10):1521-33. doi: 10.1158/1541-7786.MCR-07-2203.

4.

Therapeutic targeting of the focal adhesion complex prevents oncogenic TGF-beta signaling and metastasis.

Wendt MK, Schiemann WP.

Breast Cancer Res. 2009;11(5):R68. doi: 10.1186/bcr2360.

6.
7.

A critical role of tropomyosins in TGF-beta regulation of the actin cytoskeleton and cell motility in epithelial cells.

Bakin AV, Safina A, Rinehart C, Daroqui C, Darbary H, Helfman DM.

Mol Biol Cell. 2004 Oct;15(10):4682-94.

8.

Autocrine PDGFR signaling promotes mammary cancer metastasis.

Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, Donovan M, Cordon-Cardo C, Beug H, Grünert S.

J Clin Invest. 2006 Jun;116(6):1561-70.

9.

Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK.

Lofgren KA, Ostrander JH, Housa D, Hubbard GK, Locatelli A, Bliss RL, Schwertfeger KL, Lange CA.

Breast Cancer Res. 2011 Sep 17;13(5):R89. doi: 10.1186/bcr2946.

10.

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells.

Gomes LR, Terra LF, Wailemann RA, Labriola L, Sogayar MC.

BMC Cancer. 2012 Jan 19;12:26. doi: 10.1186/1471-2407-12-26.

11.

Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.

Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL.

Breast Cancer Res. 2012 Jul 2;14(4):R98. doi: 10.1186/bcr3217.

13.

Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

Northey JJ, Chmielecki J, Ngan E, Russo C, Annis MG, Muller WJ, Siegel PM.

Mol Cell Biol. 2008 May;28(10):3162-76. doi: 10.1128/MCB.01734-07.

15.

Attenuation of TGF-β signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model.

Biswas T, Gu X, Yang J, Ellies LG, Sun LZ.

Cancer Lett. 2014 Apr 28;346(1):129-38. doi: 10.1016/j.canlet.2013.12.018.

16.
17.

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.

Janda E, Lehmann K, Killisch I, Jechlinger M, Herzig M, Downward J, Beug H, Grünert S.

J Cell Biol. 2002 Jan 21;156(2):299-313.

18.

ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells.

Safina A, Vandette E, Bakin AV.

Oncogene. 2007 Apr 12;26(17):2407-22.

PMID:
17072348
19.

An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition.

Park CY, Min KN, Son JY, Park SY, Nam JS, Kim DK, Sheen YY.

Cancer Lett. 2014 Aug 28;351(1):72-80. doi: 10.1016/j.canlet.2014.05.006.

PMID:
24887560
20.

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