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Items: 1 to 20 of 107

1.

Formation of BCR oligomers provides a mechanism for B cell affinity discrimination.

Tsourkas PK, Somkanya C D, Yu-Yang P, Liu W, Pierce SK, Raychaudhuri S.

J Theor Biol. 2012 Aug 21;307:174-82. doi: 10.1016/j.jtbi.2012.05.008. Epub 2012 May 19.

2.

Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement.

Tsourkas PK, Liu W, Das SC, Pierce SK, Raychaudhuri S.

Cell Mol Immunol. 2012 Jan;9(1):62-74. doi: 10.1038/cmi.2011.29. Epub 2011 Sep 12.

3.

Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases.

Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A.

Sci Signal. 2013 Jan 1;6(256):ra1. doi: 10.1126/scisignal.2003220.

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5.

CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.

Fujimoto M, Poe JC, Jansen PJ, Sato S, Tedder TF.

J Immunol. 1999 Jun 15;162(12):7088-94.

6.

B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity.

Khalil AM, Cambier JC, Shlomchik MJ.

Science. 2012 Jun 1;336(6085):1178-81. doi: 10.1126/science.1213368. Epub 2012 May 3.

7.

The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.

Katkere B, Rosa S, Drake JR.

J Biol Chem. 2012 May 11;287(20):16636-44. doi: 10.1074/jbc.M112.357640. Epub 2012 Mar 27.

8.

Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.

Kroczek C, Lang C, Brachs S, Grohmann M, Dütting S, Schweizer A, Nitschke L, Feller SM, Jäck HM, Mielenz D.

J Immunol. 2010 Apr 1;184(7):3665-76. doi: 10.4049/jimmunol.0903642. Epub 2010 Mar 1.

9.

Autoinhibition and adapter function of Syk.

Kulathu Y, Grothe G, Reth M.

Immunol Rev. 2009 Nov;232(1):286-99. doi: 10.1111/j.1600-065X.2009.00837.x. Review.

PMID:
19909371
10.

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt.

Craxton A, Jiang A, Kurosaki T, Clark EA.

J Biol Chem. 1999 Oct 22;274(43):30644-50.

11.
13.

Force generation in B-cell synapses: mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination.

Tolar P, Spillane KM.

Adv Immunol. 2014;123:69-100. doi: 10.1016/B978-0-12-800266-7.00002-9. Review.

PMID:
24840948
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16.

Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling.

Kurosaki T, Takata M, Yamanashi Y, Inazu T, Taniguchi T, Yamamoto T, Yamamura H.

J Exp Med. 1994 May 1;179(5):1725-9.

17.
18.

Reconstitution of B cell antigen receptor-induced signaling events in a nonlymphoid cell line by expressing the Syk protein-tyrosine kinase.

Richards JD, Gold MR, Hourihane SL, DeFranco AL, Matsuuchi L.

J Biol Chem. 1996 Mar 15;271(11):6458-66.

20.

Antigen affinity discrimination is an intrinsic function of the B cell receptor.

Liu W, Meckel T, Tolar P, Sohn HW, Pierce SK.

J Exp Med. 2010 May 10;207(5):1095-111. doi: 10.1084/jem.20092123. Epub 2010 Apr 19.

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