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Items: 1 to 20 of 92

1.

Treatment of erythropoietin deficiency in mice with systemically administered siRNA.

Querbes W, Bogorad RL, Moslehi J, Wong J, Chan AY, Bulgakova E, Kuchimanchi S, Akinc A, Fitzgerald K, Koteliansky V, Kaelin WG Jr.

Blood. 2012 Aug 30;120(9):1916-22. doi: 10.1182/blood-2012-04-423715. Epub 2012 May 18.

2.

Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis.

Liu Q, Davidoff O, Niss K, Haase VH.

J Clin Invest. 2012 Dec;122(12):4635-44. doi: 10.1172/JCI63924. Epub 2012 Nov 1.

3.

Reactivation of hepatic EPO synthesis in mice after PHD loss.

Minamishima YA, Kaelin WG Jr.

Science. 2010 Jul 23;329(5990):407. doi: 10.1126/science.1192811.

4.

Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis.

Mastrogiannaki M, Matak P, Mathieu JR, Delga S, Mayeux P, Vaulont S, Peyssonnaux C.

Haematologica. 2012 Jun;97(6):827-34. doi: 10.3324/haematol.2011.056119. Epub 2011 Dec 29.

5.

Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC.

Frede S, Freitag P, Geuting L, Konietzny R, Fandrey J.

Blood. 2011 May 5;117(18):4905-14. doi: 10.1182/blood-2010-07-298083. Epub 2011 Mar 15. Retraction in: Blood. 2014 May 22;123(21):3365.

6.

Analysis of the role of the HIF hydroxylase family members in erythropoiesis.

Fisher TS, Lira PD, Stock JL, Perregaux DG, Brissette WH, Ozolins TR, Li B.

Biochem Biophys Res Commun. 2009 Oct 30;388(4):683-8. doi: 10.1016/j.bbrc.2009.08.058. Epub 2009 Aug 14.

PMID:
19683512
7.
8.

Hepcidin antimicrobial peptide transgenic mice exhibit features of the anemia of inflammation.

Roy CN, Mak HH, Akpan I, Losyev G, Zurakowski D, Andrews NC.

Blood. 2007 May 1;109(9):4038-44. Epub 2007 Jan 11.

9.

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.

Laitala A, Aro E, Walkinshaw G, Mäki JM, Rossi M, Heikkilä M, Savolainen ER, Arend M, Kivirikko KI, Koivunen P, Myllyharju J.

Blood. 2012 Oct 18;120(16):3336-44. doi: 10.1182/blood-2012-07-441824. Epub 2012 Sep 5.

10.

A single dose of EGLN1 siRNA yields increased erythropoiesis in nonhuman primates.

Abrams MT, Koser M, Burchard J, Strapps W, Mehmet H, Gindy M, Zaller D, Sepp-Lorenzino L, Stickens D.

Nucleic Acid Ther. 2014 Dec;24(6):405-12. doi: 10.1089/nat.2014.0495.

PMID:
25272050
11.

Why not the liver instead of the kidney?

Fandrey J.

Blood. 2012 Aug 30;120(9):1760-1. doi: 10.1182/blood-2012-06-433201. No abstract available.

12.

Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.

Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, Suzuki N.

Mol Cell Biol. 2015 Aug;35(15):2658-72. doi: 10.1128/MCB.00161-15. Epub 2015 May 26.

13.

Reevaluation of erythropoietin production by the nephron.

Nagai T, Yasuoka Y, Izumi Y, Horikawa K, Kimura M, Nakayama Y, Uematsu T, Fukuyama T, Yamazaki T, Kohda Y, Hasuike Y, Nanami M, Kuragano T, Kobayashi N, Obinata M, Tomita K, Tanoue A, Nakanishi T, Kawahara K, Nonoguchi H.

Biochem Biophys Res Commun. 2014 Jun 27;449(2):222-8. doi: 10.1016/j.bbrc.2014.05.014. Epub 2014 May 14.

14.

Erythropoietin stimulation decreases hepcidin expression through hematopoietic activity on bone marrow cells in mice.

Sasaki Y, Noguchi-Sasaki M, Yasuno H, Yorozu K, Shimonaka Y.

Int J Hematol. 2012 Dec;96(6):692-700. doi: 10.1007/s12185-012-1217-4. Epub 2012 Nov 16.

PMID:
23160767
15.

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha.

Pinto JP, Ribeiro S, Pontes H, Thowfeequ S, Tosh D, Carvalho F, Porto G.

Blood. 2008 Jun 15;111(12):5727-33. doi: 10.1182/blood-2007-08-106195. Epub 2008 Mar 7.

16.

Phlebotomies or erythropoietin injections allow mobilization of iron stores in a mouse model mimicking intensive care anemia.

Lasocki S, Millot S, Andrieu V, Lettéron P, Pilard N, Muzeau F, Thibaudeau O, Montravers P, Beaumont C.

Crit Care Med. 2008 Aug;36(8):2388-94. doi: 10.1097/CCM.0b013e31818103b9.

PMID:
18664788
17.

A mouse model of adult-onset anaemia due to erythropoietin deficiency.

Yamazaki S, Souma T, Hirano I, Pan X, Minegishi N, Suzuki N, Yamamoto M.

Nat Commun. 2013;4:1950. doi: 10.1038/ncomms2950.

PMID:
23727690
18.

Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages.

Suzuki N, Obara N, Pan X, Watanabe M, Jishage K, Minegishi N, Yamamoto M.

Mol Cell Biol. 2011 Sep;31(18):3896-905. doi: 10.1128/MCB.05463-11. Epub 2011 Jul 11.

19.

Mechanisms of anemia in CKD.

Babitt JL, Lin HY.

J Am Soc Nephrol. 2012 Oct;23(10):1631-4. Epub 2012 Aug 30. Review.

20.

Intestinal inflammation modulates expression of the iron-regulating hormone hepcidin depending on erythropoietic activity and the commensal microbiota.

Shanmugam NK, Trebicka E, Fu LL, Shi HN, Cherayil BJ.

J Immunol. 2014 Aug 1;193(3):1398-407. doi: 10.4049/jimmunol.1400278. Epub 2014 Jun 27.

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