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Items: 1 to 20 of 107

1.

Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.

Siwek W, Czapinska H, Bochtler M, Bujnicki JM, Skowronek K.

Nucleic Acids Res. 2012 Aug;40(15):7563-72. doi: 10.1093/nar/gks428. Epub 2012 May 18.

2.

Structural basis of the methylation specificity of R.DpnI.

Mierzejewska K, Siwek W, Czapinska H, Kaus-Drobek M, Radlinska M, Skowronek K, Bujnicki JM, Dadlez M, Bochtler M.

Nucleic Acids Res. 2014 Jul;42(13):8745-54. doi: 10.1093/nar/gku546. Epub 2014 Jun 25.

3.

Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI.

Shen BW, Xu D, Chan SH, Zheng Y, Zhu Z, Xu SY, Stoddard BL.

Nucleic Acids Res. 2011 Oct;39(18):8223-36. doi: 10.1093/nar/gkr543. Epub 2011 Jun 30.

4.

Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit.

Kachalova GS, Rogulin EA, Yunusova AK, Artyukh RI, Perevyazova TA, Matvienko NI, Zheleznaya LA, Bartunik HD.

J Mol Biol. 2008 Dec 12;384(2):489-502. doi: 10.1016/j.jmb.2008.09.033. Epub 2008 Sep 21.

PMID:
18835275
5.

UbaLAI is a monomeric Type IIE restriction enzyme.

Sasnauskas G, Tamulaitiene G, Tamulaitis G, Calyševa J, Laime M, Rimšeliene R, Lubys A, Siksnys V.

Nucleic Acids Res. 2017 Sep 19;45(16):9583-9594. doi: 10.1093/nar/gkx634.

6.

Mva1269I: a monomeric type IIS restriction endonuclease from Micrococcus varians with two EcoRI- and FokI-like catalytic domains.

Armalyte E, Bujnicki JM, Giedriene J, Gasiunas G, Kosiński J, Lubys A.

J Biol Chem. 2005 Dec 16;280(50):41584-94. Epub 2005 Oct 11.

7.

Restriction endonuclease MvaI is a monomer that recognizes its target sequence asymmetrically.

Kaus-Drobek M, Czapinska H, Sokołowska M, Tamulaitis G, Szczepanowski RH, Urbanke C, Siksnys V, Bochtler M.

Nucleic Acids Res. 2007;35(6):2035-46. Epub 2007 Mar 7.

8.

Functional analysis of MmeI from methanol utilizer Methylophilus methylotrophus, a subtype IIC restriction-modification enzyme related to type I enzymes.

Nakonieczna J, Kaczorowski T, Obarska-Kosinska A, Bujnicki JM.

Appl Environ Microbiol. 2009 Jan;75(1):212-23. doi: 10.1128/AEM.01322-08. Epub 2008 Nov 7.

9.

Methylation-targeted specificity of the DNA binding proteins R.DpnI and MeCP2 studied by molecular dynamics simulations.

Shanak S, Ulucan O, Helms V.

J Mol Model. 2017 May;23(5):152. doi: 10.1007/s00894-017-3318-8. Epub 2017 Apr 3.

PMID:
28374217
10.

Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.

Tamulaitiene G, Jovaisaite V, Tamulaitis G, Songailiene I, Manakova E, Zaremba M, Grazulis S, Xu SY, Siksnys V.

Nucleic Acids Res. 2017 Apr 7;45(6):3547-3558. doi: 10.1093/nar/gkw1310.

11.

Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence.

Grazulis S, Deibert M, Rimseliene R, Skirgaila R, Sasnauskas G, Lagunavicius A, Repin V, Urbanke C, Huber R, Siksnys V.

Nucleic Acids Res. 2002 Feb 15;30(4):876-85.

12.

Structure of the multimodular endonuclease FokI bound to DNA.

Wah DA, Hirsch JA, Dorner LF, Schildkraut I, Aggarwal AK.

Nature. 1997 Jul 3;388(6637):97-100.

PMID:
9214510
13.

The recognition domain of the BpuJI restriction endonuclease in complex with cognate DNA at 1.3-A resolution.

Sukackaite R, Grazulis S, Bochtler M, Siksnys V.

J Mol Biol. 2008 May 16;378(5):1084-93. doi: 10.1016/j.jmb.2008.03.041. Epub 2008 Mar 28.

PMID:
18433771
14.

Characterization of eukaryotic DNA N(6)-methyladenine by a highly sensitive restriction enzyme-assisted sequencing.

Luo GZ, Wang F, Weng X, Chen K, Hao Z, Yu M, Deng X, Liu J, He C.

Nat Commun. 2016 Apr 15;7:11301. doi: 10.1038/ncomms11301.

15.

I-Ssp6803I: the first homing endonuclease from the PD-(D/E)XK superfamily exhibits an unusual mode of DNA recognition.

Orlowski J, Boniecki M, Bujnicki JM.

Bioinformatics. 2007 Mar 1;23(5):527-30. Epub 2007 Jan 22.

PMID:
17242028
16.

Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution.

Lukacs CM, Kucera R, Schildkraut I, Aggarwal AK.

Nat Struct Biol. 2000 Feb;7(2):134-40.

PMID:
10655616
17.

Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI.

Tamulaitis G, Rutkauskas M, Zaremba M, Grazulis S, Tamulaitiene G, Siksnys V.

Nucleic Acids Res. 2015 Sep 18;43(16):8100-10. doi: 10.1093/nar/gkv768. Epub 2015 Aug 3.

18.

Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway.

Moure CM, Gimble FS, Quiocho FA.

Nucleic Acids Res. 2008 Jun;36(10):3287-96. doi: 10.1093/nar/gkn178. Epub 2008 Apr 19.

19.
20.

Type II restriction endonuclease R.Hpy188I belongs to the GIY-YIG nuclease superfamily, but exhibits an unusual active site.

Kaminska KH, Kawai M, Boniecki M, Kobayashi I, Bujnicki JM.

BMC Struct Biol. 2008 Nov 14;8:48. doi: 10.1186/1472-6807-8-48.

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