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Items: 1 to 20 of 105

1.

Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases.

Moynié L, Giraud MF, Breton A, Boissier F, Daignan-Fornier B, Dautant A.

Protein Sci. 2012 Aug;21(8):1185-96. doi: 10.1002/pro.2098. Epub 2012 Jun 11.

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Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis.

Chen Q, Liang Y, Su X, Gu X, Zheng X, Luo M.

J Mol Biol. 2005 May 20;348(5):1199-210. Epub 2005 Apr 7.

PMID:
15854655
6.

Crystal structures of free, IMP-, and GMP-bound Escherichia coli hypoxanthine phosphoribosyltransferase.

Guddat LW, Vos S, Martin JL, Keough DT, de Jersey J.

Protein Sci. 2002 Jul;11(7):1626-38.

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Unusual substrate specificity of a chimeric hypoxanthine-guanine phosphoribosyltransferase containing segments from the Plasmodium falciparum and human enzymes.

Sujay Subbayya IN, Sukumaran S, Shivashankar K, Balaram H.

Biochem Biophys Res Commun. 2000 Jun 7;272(2):596-602.

PMID:
10833458
9.

Crystal structure of a chimera of human and Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferases provides insights into oligomerization.

Gayathri P, Sujay Subbayya IN, Ashok CS, Selvi TS, Balaram H, Murthy MR.

Proteins. 2008 Dec;73(4):1010-20. doi: 10.1002/prot.22129.

PMID:
18536021
10.

Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase.

Ullman B, Cyr N, Choi K, Jardim A.

Int J Biochem Cell Biol. 2010 Feb;42(2):253-62. doi: 10.1016/j.biocel.2009.10.020. Epub 2009 Oct 25.

PMID:
19861168
11.

Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase.

Monzani PS, Trapani S, Thiemann OH, Oliva G.

BMC Struct Biol. 2007 Sep 25;7:59.

12.

Structures of hypoxanthine-guanine phosphoribosyltransferase (TTHA0220) from Thermus thermophilus HB8.

Kanagawa M, Baba S, Ebihara A, Shinkai A, Hirotsu K, Mega R, Kim K, Kuramitsu S, Sampei G, Kawai G.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Aug 1;66(Pt 8):893-8. doi: 10.1107/S1744309110023079. Epub 2010 Jul 27.

13.

Crystal structures of Apo and GMP bound hypoxanthine-guanine phosphoribosyltransferase from Legionella pneumophila and the implications in gouty arthritis.

Zhang N, Gong X, Lu M, Chen X, Qin X, Ge H.

J Struct Biol. 2016 Jun;194(3):311-6. doi: 10.1016/j.jsb.2016.03.007. Epub 2016 Mar 8.

PMID:
26968365
14.

First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.

Eng WS, Hocková D, Špaček P, Janeba Z, West NP, Woods K, Naesens LM, Keough DT, Guddat LW.

J Med Chem. 2015 Jun 11;58(11):4822-38. doi: 10.1021/acs.jmedchem.5b00611. Epub 2015 May 13.

PMID:
25915781
15.

A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.

Wang F, Shi W, Nieves E, Angeletti RH, Schramm VL, Grubmeyer C.

Biochemistry. 2001 Jul 10;40(27):8043-54.

PMID:
11434773
16.

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).

Shi W, Munagala NR, Wang CC, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC.

Biochemistry. 2000 Jun 13;39(23):6781-90.

PMID:
10841757
17.

Structural analysis of adenine phosphoribosyltransferase from Saccharomyces cerevisiae.

Shi W, Tanaka KS, Crother TR, Taylor MW, Almo SC, Schramm VL.

Biochemistry. 2001 Sep 11;40(36):10800-9.

PMID:
11535055
18.

Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase.

Canyuk B, Medrano FJ, Wenck MA, Focia PJ, Eakin AE, Craig SP 3rd.

J Mol Biol. 2004 Jan 23;335(4):905-21.

PMID:
14698288
19.

Crystal structure of Escherichia coli xanthine phosphoribosyltransferase.

Vos S, de Jersey J, Martin JL.

Biochemistry. 1997 Apr 8;36(14):4125-34.

PMID:
9100006
20.

Plasmodium falciparum hypoxanthine guanine phosphoribosyltransferase. Stability studies on the product-activated enzyme.

Raman J, Ashok CS, Subbayya SI, Anand RP, Selvi ST, Balaram H.

FEBS J. 2005 Apr;272(8):1900-11.

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