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Items: 1 to 20 of 111

1.

Fibroblast activation protein-α: a key modulator of the microenvironment in multiple pathologies.

Kelly T, Huang Y, Simms AE, Mazur A.

Int Rev Cell Mol Biol. 2012;297:83-116. doi: 10.1016/B978-0-12-394308-8.00003-0. Review.

PMID:
22608558
2.
3.

Fibroblast activation protein in remodeling tissues.

Jacob M, Chang L, Puré E.

Curr Mol Med. 2012 Dec;12(10):1220-43. Review.

PMID:
22834826
4.

Fibroblast activation protein alpha is expressed by transformed and stromal cells and is associated with mesenchymal features in glioblastoma.

Busek P, Balaziova E, Matrasova I, Hilser M, Tomas R, Syrucek M, Zemanova Z, Krepela E, Belacek J, Sedo A.

Tumour Biol. 2016 Oct;37(10):13961-13971. Epub 2016 Aug 4.

PMID:
27492457
5.

Effects of the fibroblast activation protein on the invasion and migration of gastric cancer.

Wang RF, Zhang LH, Shan LH, Sun WG, Chai CC, Wu HM, Ibla JC, Wang LF, Liu JR.

Exp Mol Pathol. 2013 Dec;95(3):350-56.

PMID:
24422232
6.

Identification of selective and potent inhibitors of fibroblast activation protein and prolyl oligopeptidase.

Poplawski SE, Lai JH, Li Y, Jin Z, Liu Y, Wu W, Wu Y, Zhou Y, Sudmeier JL, Sanford DG, Bachovchin WW.

J Med Chem. 2013 May 9;56(9):3467-77. doi: 10.1021/jm400351a. Epub 2013 Apr 29.

7.

Fibroblast activation protein-α in fibrogenic disorders and cancer: more than a prolyl-specific peptidase?

Juillerat-Jeanneret L, Tafelmeyer P, Golshayan D.

Expert Opin Ther Targets. 2017 Oct;21(10):977-991. doi: 10.1080/14728222.2017.1370455. Epub 2017 Aug 30. Review.

PMID:
28829211
8.

Increased expression of fibroblast activation protein-alpha in keloid fibroblasts: implications for development of a novel treatment option.

Dienus K, Bayat A, Gilmore BF, Seifert O.

Arch Dermatol Res. 2010 Dec;302(10):725-31. doi: 10.1007/s00403-010-1084-x. Epub 2010 Sep 26.

PMID:
20872224
9.

Suppression of tumor growth in mice by rationally designed pseudopeptide inhibitors of fibroblast activation protein and prolyl oligopeptidase.

Jackson KW, Christiansen VJ, Yadav VR, Silasi-Mansat R, Lupu F, Awasthi V, Zhang RR, McKee PA.

Neoplasia. 2015 Jan;17(1):43-54. doi: 10.1016/j.neo.2014.11.002.

10.

Fibroblast activation protein: A potential therapeutic target in cancer.

Liu R, Li H, Liu L, Yu J, Ren X.

Cancer Biol Ther. 2012 Feb 1;13(3):123-9. doi: 10.4161/cbt.13.3.18696. Epub 2012 Feb 1. Review.

PMID:
22236832
11.

Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata.

Brokopp CE, Schoenauer R, Richards P, Bauer S, Lohmann C, Emmert MY, Weber B, Winnik S, Aikawa E, Graves K, Genoni M, Vogt P, Lüscher TF, Renner C, Hoerstrup SP, Matter CM.

Eur Heart J. 2011 Nov;32(21):2713-22. doi: 10.1093/eurheartj/ehq519. Epub 2011 Feb 2.

12.

Inhibition of fibroblast activation protein and dipeptidylpeptidase 4 increases cartilage invasion by rheumatoid arthritis synovial fibroblasts.

Ospelt C, Mertens JC, Jüngel A, Brentano F, Maciejewska-Rodriguez H, Huber LC, Hemmatazad H, Wüest T, Knuth A, Gay RE, Michel BA, Gay S, Renner C, Bauer S.

Arthritis Rheum. 2010 May;62(5):1224-35. doi: 10.1002/art.27395.

13.

Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.

Scanlan MJ, Raj BK, Calvo B, Garin-Chesa P, Sanz-Moncasi MP, Healey JH, Old LJ, Rettig WJ.

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5657-61.

14.

Cleavage-site specificity of prolyl endopeptidase FAP investigated with a full-length protein substrate.

Huang CH, Suen CS, Lin CT, Chien CH, Lee HY, Chung KM, Tsai TY, Jiaang WT, Hwang MJ, Chen X.

J Biochem. 2011 Jun;149(6):685-92. doi: 10.1093/jb/mvr017. Epub 2011 Feb 1.

PMID:
21288888
15.

Fibroblast activation protein α in tumor microenvironment: recent progression and implications (review).

Zi F, He J, He D, Li Y, Yang L, Cai Z.

Mol Med Rep. 2015 May;11(5):3203-11. doi: 10.3892/mmr.2015.3197. Epub 2015 Jan 14. Review.

16.

Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathway.

Zi FM, He JS, Li Y, Wu C, Wu WJ, Yang Y, Wang LJ, He DH, Yang L, Zhao Y, Zheng GF, Han XY, Huang H, Yi Q, Cai Z.

Cancer Biol Ther. 2014 Oct;15(10):1413-22. doi: 10.4161/cbt.29924. Epub 2014 Jul 21.

17.

Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy.

Brennen WN, Isaacs JT, Denmeade SR.

Mol Cancer Ther. 2012 Feb;11(2):257-66. doi: 10.1158/1535-7163.MCT-11-0340. Review.

18.

The application of the fibroblast activation protein α-targeted immunotherapy strategy.

Jiang GM, Xu W, Du J, Zhang KS, Zhang QG, Wang XW, Liu ZG, Liu SQ, Xie WY, Liu HF, Liu JS, Wu BP.

Oncotarget. 2016 May 31;7(22):33472-82. doi: 10.18632/oncotarget.8098. Review.

19.

Fibroblast activation protein regulates tumor-associated fibroblasts and epithelial ovarian cancer cells.

Lai D, Ma L, Wang F.

Int J Oncol. 2012 Aug;41(2):541-50. doi: 10.3892/ijo.2012.1475. Epub 2012 May 14.

PMID:
22614695
20.

Specific inhibition of fibroblast activation protein (FAP)-alpha prevents tumor progression in vitro.

Teichgräber V, Monasterio C, Chaitanya K, Boger R, Gordon K, Dieterle T, Jäger D, Bauer S.

Adv Med Sci. 2015 Sep;60(2):264-72. doi: 10.1016/j.advms.2015.04.006. Epub 2015 May 11.

PMID:
26057860

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