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Transcriptome analysis using next generation sequencing reveals molecular signatures of diabetic retinopathy and efficacy of candidate drugs.

Kandpal RP, Rajasimha HK, Brooks MJ, Nellissery J, Wan J, Qian J, Kern TS, Swaroop A.

Mol Vis. 2012;18:1123-46.


Hyperglycaemia-induced pro-inflammatory responses by retinal Müller glia are regulated by the receptor for advanced glycation end-products (RAGE).

Zong H, Ward M, Madden A, Yong PH, Limb GA, Curtis TM, Stitt AW.

Diabetologia. 2010 Dec;53(12):2656-66. doi: 10.1007/s00125-010-1900-z.


Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice.

McVicar CM, Ward M, Colhoun LM, Guduric-Fuchs J, Bierhaus A, Fleming T, Schlotterer A, Kolibabka M, Hammes HP, Chen M, Stitt AW.

Diabetologia. 2015 May;58(5):1129-37. doi: 10.1007/s00125-015-3523-x.


Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation.

Veluthakal R, Kumar B, Mohammad G, Kowluru A, Kowluru RA.

Cell Physiol Biochem. 2015;36(1):208-20. doi: 10.1159/000374065.


Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.

El-Remessy AB, Rajesh M, Mukhopadhyay P, Horváth B, Patel V, Al-Gayyar MM, Pillai BA, Pacher P.

Diabetologia. 2011 Jun;54(6):1567-78. doi: 10.1007/s00125-011-2061-4.


The role of high mobility group box 1 (HMGB-1) in the diabetic retinopathy inflammation and apoptosis.

Yu Y, Yang L, Lv J, Huang X, Yi J, Pei C, Shao Y.

Int J Clin Exp Pathol. 2015 Jun 1;8(6):6807-13.


Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products.

Kaji Y, Usui T, Ishida S, Yamashiro K, Moore TC, Moore J, Yamamoto Y, Yamamoto H, Adamis AP.

Invest Ophthalmol Vis Sci. 2007 Feb;48(2):858-65.


Pigment-epithelium-derived factor suppresses expression of receptor for advanced glycation end products in the eye of diabetic rats.

Yamagishi S, Matsui T, Nakamura K, Yoshida T, Takeuchi M, Inoue H, Yoshida Y, Imaizumi T.

Ophthalmic Res. 2007;39(2):92-7.


Sulforaphane inhibits advanced glycation end product-induced pericyte damage by reducing expression of receptor for advanced glycation end products.

Maeda S, Matsui T, Ojima A, Takeuchi M, Yamagishi S.

Nutr Res. 2014 Sep;34(9):807-13. doi: 10.1016/j.nutres.2014.08.010.


Diabetes-induced impairment in visual function in mice: contributions of p38 MAPK, rage, leukocytes, and aldose reductase.

Lee CA, Li G, Patel MD, Petrash JM, Benetz BA, Veenstra A, Amengual J, von Lintig J, Burant CJ, Tang J, Kern TS.

Invest Ophthalmol Vis Sci. 2014 May 2;55(5):2904-10. doi: 10.1167/iovs.13-11659.


Receptor for advanced glycation end product expression in experimental diabetic retinopathy.

Wang Y, Vom Hagen F, Pfister F, Bierhaus A, Feng Y, Gans R, Hammes HP.

Ann N Y Acad Sci. 2008 Apr;1126:42-5. doi: 10.1196/annals.1433.063.


Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice.

Mykkänen OT, Kalesnykas G, Adriaens M, Evelo CT, Törrönen R, Kaarniranta K.

Mol Vis. 2012;18:2338-51.


A cross talk between class A scavenger receptor and receptor for advanced glycation end-products contributes to diabetic retinopathy.

Ma K, Xu Y, Wang C, Li N, Li K, Zhang Y, Li X, Yang Q, Zhang H, Zhu X, Bai H, Ben J, Ding Q, Li K, Jiang Q, Xu Y, Chen Q.

Am J Physiol Endocrinol Metab. 2014 Dec 15;307(12):E1153-65. doi: 10.1152/ajpendo.00378.2014.


Retinal localization of the glutamate receptor GluR2 and GluR2-regulating proteins in diabetic rats.

Semkova I, Huemmeke M, Ho MS, Merkl B, Abari E, Paulsson M, Joussen AM, Plomann M.

Exp Eye Res. 2010 Feb;90(2):244-53. doi: 10.1016/j.exer.2009.10.012. Erratum in: Exp Eye Res. 2015 May;134:159-60.


Retinal upregulation of inflammatory and proangiogenic markers in a model of neonatal diabetic rats fed on a high-fat-diet.

Mancini JE, Ortiz G, Croxatto JO, Gallo JE.

BMC Ophthalmol. 2013 Apr 15;13:14. doi: 10.1186/1471-2415-13-14.


Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes.

Klaassen I, Hughes JM, Vogels IM, Schalkwijk CG, Van Noorden CJ, Schlingemann RO.

Exp Eye Res. 2009 Jun 15;89(1):4-15. doi: 10.1016/j.exer.2009.01.006.


Genistein attenuates retinal inflammation associated with diabetes by targeting of microglial activation.

Ibrahim AS, El-Shishtawy MM, Peña A Jr, Liou GI.

Mol Vis. 2010 Oct 8;16:2033-42.

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