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Items: 1 to 20 of 163

1.

Repetitive elements and enforced transcriptional repression co-operate to enhance DNA methylation spreading into a promoter CpG-island.

Zhang Y, Shu J, Si J, Shen L, Estecio MR, Issa JP.

Nucleic Acids Res. 2012 Aug;40(15):7257-68. Epub 2012 May 17.

3.

DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.

Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G.

Hum Mol Genet. 2011 Nov 15;20(22):4299-310. doi: 10.1093/hmg/ddr356. Epub 2011 Aug 11.

4.

Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter.

Strunnikova M, Schagdarsurengin U, Kehlen A, Garbe JC, Stampfer MR, Dammann R.

Mol Cell Biol. 2005 May;25(10):3923-33.

5.

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.

O'Hagan HM, Mohammad HP, Baylin SB.

PLoS Genet. 2008 Aug 15;4(8):e1000155. doi: 10.1371/journal.pgen.1000155.

6.

Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.

Hinshelwood RA, Melki JR, Huschtscha LI, Paul C, Song JZ, Stirzaker C, Reddel RR, Clark SJ.

Hum Mol Genet. 2009 Aug 15;18(16):3098-109. doi: 10.1093/hmg/ddp251. Epub 2009 May 28.

PMID:
19477956
7.

Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

Yuan J, Luo RZ, Fujii S, Wang L, Hu W, Andreeff M, Pan Y, Kadota M, Oshimura M, Sahin AA, Issa JP, Bast RC Jr, Yu Y.

Cancer Res. 2003 Jul 15;63(14):4174-80.

8.
9.

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

Song JZ, Stirzaker C, Harrison J, Melki JR, Clark SJ.

Oncogene. 2002 Feb 7;21(7):1048-61.

10.

CpG content affects gene silencing in mice: evidence from novel transgenes.

Chevalier-Mariette C, Henry I, Montfort L, Capgras S, Forlani S, Muschler J, Nicolas JF.

Genome Biol. 2003;4(9):R53. Epub 2003 Aug 14.

12.
14.

DNA methylation: the nuts and bolts of repression.

Miranda TB, Jones PA.

J Cell Physiol. 2007 Nov;213(2):384-90. Review.

PMID:
17708532
15.
16.

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.

Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod AR.

Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23.

PMID:
12496760
17.

Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.

Aoyama T, Okamoto T, Nagayama S, Nishijo K, Ishibe T, Yasura K, Nakayama T, Nakamura T, Toguchida J.

J Biol Chem. 2004 Jul 2;279(27):28789-97. Epub 2004 Apr 23.

18.
19.

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer.

Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG.

Hum Mol Genet. 2001 Apr;10(7):687-92. Review.

PMID:
11257100
20.

DNA methylation is the primary silencing mechanism for a set of germ line- and tumor-specific genes with a CpG-rich promoter.

De Smet C, Lurquin C, Lethé B, Martelange V, Boon T.

Mol Cell Biol. 1999 Nov;19(11):7327-35.

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