Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 138


Elevated cyclin G2 expression intersects with DNA damage checkpoint signaling and is required for a potent G2/M checkpoint arrest response to doxorubicin.

Zimmermann M, Arachchige-Don AS, Donaldson MS, Dallapiazza RF, Cowan CE, Horne MC.

J Biol Chem. 2012 Jun 29;287(27):22838-53. doi: 10.1074/jbc.M112.376855.


Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.

Lossaint G, Besnard E, Fisher D, Piette J, Dulić V.

Oncogene. 2011 Oct 13;30(41):4261-74. doi: 10.1038/onc.2011.135.


Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.

Shibata A, Barton O, Noon AT, Dahm K, Deckbar D, Goodarzi AA, Löbrich M, Jeggo PA.

Mol Cell Biol. 2010 Jul;30(13):3371-83. doi: 10.1128/MCB.01644-09.


RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation.

Yan Y, Greer PM, Cao PT, Kolb RH, Cowan KH.

Breast Cancer Res. 2012 Apr 11;14(2):R60.


Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage.

Tsvetkov L, Stern DF.

Cell Cycle. 2005 Jan;4(1):166-71.


Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.

Bork U, Lee WK, Kuchler A, Dittmar T, Thévenod F.

Am J Physiol Renal Physiol. 2010 Feb;298(2):F255-65. doi: 10.1152/ajprenal.00273.2009.


Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.

Palii SS, Cui Y, Innes CL, Paules RS.

Cell Cycle. 2013 Apr 1;12(7):1105-18. doi: 10.4161/cc.24127.


Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway.

Meng AG, Jiang LL.

Acta Pharmacol Sin. 2009 Apr;30(4):442-50. doi: 10.1038/aps.2009.20.


Large T antigen promotes JC virus replication in G2-arrested cells by inducing ATM- and ATR-mediated G2 checkpoint signaling.

Orba Y, Suzuki T, Makino Y, Kubota K, Tanaka S, Kimura T, Sawa H.

J Biol Chem. 2010 Jan 8;285(2):1544-54. doi: 10.1074/jbc.M109.064311.


Mice lacking protein phosphatase 5 are defective in ataxia telangiectasia mutated (ATM)-mediated cell cycle arrest.

Yong W, Bao S, Chen H, Li D, Sánchez ER, Shou W.

J Biol Chem. 2007 May 18;282(20):14690-4.


STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Retraction in: J Cell Sci. 2015 Mar 1;128(5):1064.


4-Hydroxynonenal induces G2/M phase cell cycle arrest by activation of the ataxia telangiectasia mutated and Rad3-related protein (ATR)/checkpoint kinase 1 (Chk1) signaling pathway.

Chaudhary P, Sharma R, Sahu M, Vishwanatha JK, Awasthi S, Awasthi YC.

J Biol Chem. 2013 Jul 12;288(28):20532-46. doi: 10.1074/jbc.M113.467662.


Resveratrol analogue (E)-8-acetoxy-2-[2-(3,4-diacetoxyphenyl)ethenyl]-quinazoline induces G₂/M cell cycle arrest through the activation of ATM/ATR in human cervical carcinoma HeLa cells.

Kim JY, Choi HE, Lee HH, Shin JS, Shin DH, Choi JH, Lee YS, Lee KT.

Oncol Rep. 2015 May;33(5):2639-47. doi: 10.3892/or.2015.3871.


Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

Zhang X, Succi J, Feng Z, Prithivirajsingh S, Story MD, Legerski RJ.

Mol Cell Biol. 2004 Oct;24(20):9207-20.


Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.

Ouyang G, Yao L, Ruan K, Song G, Mao Y, Bao S.

Cell Biol Int. 2009 Dec;33(12):1237-44. doi: 10.1016/j.cellbi.2009.08.011.


Revised genetic requirements for the decatenation G2 checkpoint: the role of ATM.

Bower JJ, Zhou Y, Zhou T, Simpson DA, Arlander SJ, Paules RS, Cordeiro-Stone M, Kaufmann WK.

Cell Cycle. 2010 Apr 15;9(8):1617-28.


Recruitment of cyclin G2 to promyelocytic leukemia nuclear bodies promotes dephosphorylation of γH2AX following treatment with ionizing radiation.

Naito Y, Yabuta N, Sato J, Ohno S, Sakata M, Kasama T, Ikawa M, Nojima H.

Cell Cycle. 2013 Jun 1;12(11):1773-84. doi: 10.4161/cc.24878.


Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway.

Lee HJ, Hwang HI, Jang YJ.

Cell Cycle. 2010 Jun 15;9(12):2389-98.


Tachpyridine, a metal chelator, induces G2 cell-cycle arrest, activates checkpoint kinases, and sensitizes cells to ionizing radiation.

Turner J, Koumenis C, Kute TE, Planalp RP, Brechbiel MW, Beardsley D, Cody B, Brown KD, Torti FM, Torti SV.

Blood. 2005 Nov 1;106(9):3191-9.

Items per page

Supplemental Content

Support Center