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Items: 1 to 20 of 114

1.

Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability.

Lucas R, Yang G, Gorshkov BA, Zemskov EA, Sridhar S, Umapathy NS, Jezierska-Drutel A, Alieva IB, Leustik M, Hossain H, Fischer B, Catravas JD, Verin AD, Pittet JF, Caldwell RB, Mitchell TJ, Cederbaum SD, Fulton DJ, Matthay MA, Caldwell RW, Romero MJ, Chakraborty T.

Am J Respir Cell Mol Biol. 2012 Oct;47(4):445-53. doi: 10.1165/rcmb.2011-0332OC. Epub 2012 May 10.

2.

Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema.

Lucas R, Sridhar S, Rick FG, Gorshkov B, Umapathy NS, Yang G, Oseghale A, Verin AD, Chakraborty T, Matthay MA, Zemskov EA, White R, Block NL, Schally AV.

Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2084-9. doi: 10.1073/pnas.1121075109. Epub 2012 Jan 23.

3.

The lectin-like domain of TNF protects from listeriolysin-induced hyperpermeability in human pulmonary microvascular endothelial cells - a crucial role for protein kinase C-alpha inhibition.

Xiong C, Yang G, Kumar S, Aggarwal S, Leustik M, Snead C, Hamacher J, Fischer B, Umapathy NS, Hossain H, Wendel A, Catravas JD, Verin AD, Fulton D, Black SM, Chakraborty T, Lucas R.

Vascul Pharmacol. 2010 May-Jun;52(5-6):207-13. doi: 10.1016/j.vph.2009.12.010. Epub 2010 Jan 13.

4.

Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction.

Czikora I, Sridhar S, Gorshkov B, Alieva IB, Kasa A, Gonzales J, Potapenko O, Umapathy NS, Pillich H, Rick FG, Block NL, Verin AD, Chakraborty T, Matthay MA, Schally AV, Lucas R.

Front Physiol. 2014 Jul 15;5:259. doi: 10.3389/fphys.2014.00259. eCollection 2014.

5.

Sirolimus-FKBP12.6 impairs endothelial barrier function through protein kinase C-α activation and disruption of the p120-vascular endothelial cadherin interaction.

Habib A, Karmali V, Polavarapu R, Akahori H, Cheng Q, Pachura K, Kolodgie FD, Finn AV.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2425-31. doi: 10.1161/ATVBAHA.113.301659. Epub 2013 Jul 25.

6.
7.

Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction.

Czikora I, Alli AA, Sridhar S, Matthay MA, Pillich H, Hudel M, Berisha B, Gorshkov B, Romero MJ, Gonzales J, Wu G, Huo Y, Su Y, Verin AD, Fulton D, Chakraborty T, Eaton DC, Lucas R.

Front Immunol. 2017 Jul 21;8:842. doi: 10.3389/fimmu.2017.00842. eCollection 2017.

8.

PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity.

Vandenbroucke St Amant E, Tauseef M, Vogel SM, Gao XP, Mehta D, Komarova YA, Malik AB.

Circ Res. 2012 Aug 31;111(6):739-49. doi: 10.1161/CIRCRESAHA.112.269654. Epub 2012 Jul 12.

9.

Heat shock protein 90 inhibitors prevent LPS-induced endothelial barrier dysfunction by disrupting RhoA signaling.

Joshi AD, Dimitropoulou C, Thangjam G, Snead C, Feldman S, Barabutis N, Fulton D, Hou Y, Kumar S, Patel V, Gorshkov B, Verin AD, Black SM, Catravas JD.

Am J Respir Cell Mol Biol. 2014 Jan;50(1):170-9. doi: 10.1165/rcmb.2012-0496OC.

10.

Role of platelet-activating factor in pneumolysin-induced acute lung injury.

Witzenrath M, Gutbier B, Owen JS, Schmeck B, Mitchell TJ, Mayer K, Thomas MJ, Ishii S, Rosseau S, Suttorp N, Schütte H.

Crit Care Med. 2007 Jul;35(7):1756-62.

PMID:
17522574
11.

Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase.

Aslam M, Schluter KD, Rohrbach S, Rafiq A, Nazli S, Piper HM, Noll T, Schulz R, Gündüz D.

J Physiol. 2013 Jan 15;591(2):461-73. doi: 10.1113/jphysiol.2012.237834. Epub 2012 Oct 22.

12.

A novel approach to prevent endothelial hyperpermeability: the Crataegus extract WS® 1442 targets the cAMP/Rap1 pathway.

Bubik MF, Willer EA, Bihari P, Jürgenliemk G, Ammer H, Krombach F, Zahler S, Vollmar AM, Fürst R.

J Mol Cell Cardiol. 2012 Jan;52(1):196-205. doi: 10.1016/j.yjmcc.2011.10.020. Epub 2011 Oct 31.

PMID:
22085704
13.

Changes in endothelial connexin 43 expression inversely correlate with microvessel permeability and VE-cadherin expression in endotoxin-challenged lungs.

Kandasamy K, Escue R, Manna J, Adebiyi A, Parthasarathi K.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 15;309(6):L584-92. doi: 10.1152/ajplung.00211.2014. Epub 2015 Jul 10.

14.

Opposing effects of the angiopoietins on the thrombin-induced permeability of human pulmonary microvascular endothelial cells.

van der Heijden M, van Nieuw Amerongen GP, van Bezu J, Paul MA, Groeneveld AB, van Hinsbergh VW.

PLoS One. 2011;6(8):e23448. doi: 10.1371/journal.pone.0023448. Epub 2011 Aug 15.

15.

Dual function of pneumolysin in the early pathogenesis of murine pneumococcal pneumonia.

Rubins JB, Charboneau D, Paton JC, Mitchell TJ, Andrew PW, Janoff EN.

J Clin Invest. 1995 Jan;95(1):142-50.

16.

RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction.

Venkatesh D, Fredette N, Rostama B, Tang Y, Vary CP, Liaw L, Urs S.

Arterioscler Thromb Vasc Biol. 2011 Apr;31(4):876-82. doi: 10.1161/ATVBAHA.110.221945. Epub 2011 Jan 27.

17.

Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways.

Sun Y, Hu G, Zhang X, Minshall RD.

Circ Res. 2009 Sep 25;105(7):676-85, 15 p following 685. doi: 10.1161/CIRCRESAHA.109.201673. Epub 2009 Aug 27.

18.

Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability.

Zhao YD, Ohkawara H, Vogel SM, Malik AB, Zhao YY.

Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L36-44. doi: 10.1152/ajplung.00064.2009. Epub 2009 Oct 30.

19.

Tissue inhibitor of metalloproteinases 3-dependent microvascular endothelial cell barrier function is disrupted under septic conditions.

Arpino V, Mehta S, Wang L, Bird R, Rohan M, Pape C, Gill SE.

Am J Physiol Heart Circ Physiol. 2016 Jun 1;310(11):H1455-67. doi: 10.1152/ajpheart.00796.2015. Epub 2016 Mar 18.

20.

Arginase 1: an unexpected mediator of pulmonary capillary barrier dysfunction in models of acute lung injury.

Lucas R, Czikora I, Sridhar S, Zemskov EA, Oseghale A, Circo S, Cederbaum SD, Chakraborty T, Fulton DJ, Caldwell RW, Romero MJ.

Front Immunol. 2013 Aug 7;4:228. doi: 10.3389/fimmu.2013.00228. eCollection 2013.

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