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Items: 1 to 20 of 252

1.

Pancreatic cancer therapy by systemic administration of VEGF siRNA contained in calcium phosphate/charge-conversional polymer hybrid nanoparticles.

Pittella F, Miyata K, Maeda Y, Suma T, Watanabe S, Chen Q, Christie RJ, Osada K, Nishiyama N, Kataoka K.

J Control Release. 2012 Aug 10;161(3):868-74. doi: 10.1016/j.jconrel.2012.05.005. Epub 2012 May 11.

PMID:
22580114
2.

Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity.

Pittella F, Zhang M, Lee Y, Kim HJ, Tockary T, Osada K, Ishii T, Miyata K, Nishiyama N, Kataoka K.

Biomaterials. 2011 Apr;32(11):3106-14. doi: 10.1016/j.biomaterials.2010.12.057. Epub 2011 Jan 26.

PMID:
21272932
3.

PEG-detachable cationic polyaspartamide derivatives bearing stearoyl moieties for systemic siRNA delivery toward subcutaneous BxPC3 pancreatic tumor.

Kim HJ, Oba M, Pittella F, Nomoto T, Cabral H, Matsumoto Y, Miyata K, Nishiyama N, Kataoka K.

J Drug Target. 2012 Jan;20(1):33-42. doi: 10.3109/1061186X.2011.632010. Epub 2011 Nov 8.

PMID:
22066783
4.

Systemic siRNA delivery to a spontaneous pancreatic tumor model in transgenic mice by PEGylated calcium phosphate hybrid micelles.

Pittella F, Cabral H, Maeda Y, Mi P, Watanabe S, Takemoto H, Kim HJ, Nishiyama N, Miyata K, Kataoka K.

J Control Release. 2014 Mar 28;178:18-24. doi: 10.1016/j.jconrel.2014.01.008. Epub 2014 Jan 15.

PMID:
24440662
5.

PEGylated carboxymethyl chitosan/calcium phosphate hybrid anionic nanoparticles mediated hTERT siRNA delivery for anticancer therapy.

Xie Y, Qiao H, Su Z, Chen M, Ping Q, Sun M.

Biomaterials. 2014 Sep;35(27):7978-91. doi: 10.1016/j.biomaterials.2014.05.068. Epub 2014 Jun 14.

PMID:
24939077
6.

Cytoplasm-responsive nanocarriers conjugated with a functional cell-penetrating peptide for systemic siRNA delivery.

Tanaka K, Kanazawa T, Horiuchi S, Ando T, Sugawara K, Takashima Y, Seta Y, Okada H.

Int J Pharm. 2013 Oct 15;455(1-2):40-7. doi: 10.1016/j.ijpharm.2013.07.069. Epub 2013 Aug 1.

PMID:
23911914
7.

Systemic delivery of therapeutic small interfering RNA using a pH-triggered amphiphilic poly-L-lysine nanocarrier to suppress prostate cancer growth in mice.

Guo J, Cheng WP, Gu J, Ding C, Qu X, Yang Z, O'Driscoll C.

Eur J Pharm Sci. 2012 Apr 11;45(5):521-32. doi: 10.1016/j.ejps.2011.11.024. Epub 2011 Dec 11.

PMID:
22186295
8.
9.

Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles.

Maeda Y, Pittella F, Nomoto T, Takemoto H, Nishiyama N, Miyata K, Kataoka K.

Macromol Rapid Commun. 2014 Jul;35(13):1211-5. doi: 10.1002/marc.201400049. Epub 2014 Apr 8.

PMID:
24715658
10.

Biocompatible and colloidally stabilized mPEG-PE/calcium phosphate hybrid nanoparticles loaded with siRNAs targeting tumors.

Gao P, Zhang X, Wang H, Zhang Q, Li H, Li Y, Duan Y.

Oncotarget. 2016 Jan 19;7(3):2855-66. doi: 10.18632/oncotarget.6428.

11.

A study of the suppressive effect on human pancreatic adenocarcinoma cell proliferation and angiogenesis by stable plasmid-based siRNA silencing of c-Src gene expression.

Zhao X, Li DC, Zhao H, Li Z, Wang JX, Zhu DM, Zhou J, Cen JN.

Oncol Rep. 2012 Mar;27(3):628-36. doi: 10.3892/or.2011.1602. Epub 2011 Dec 21.

PMID:
22200682
12.

Single-step assembly of cationic lipid-polymer hybrid nanoparticles for systemic delivery of siRNA.

Yang XZ, Dou S, Wang YC, Long HY, Xiong MH, Mao CQ, Yao YD, Wang J.

ACS Nano. 2012 Jun 26;6(6):4955-65. doi: 10.1021/nn300500u. Epub 2012 Jun 5.

PMID:
22646867
14.

Intracellular siRNA delivery system using polyelectrolyte complex micelles prepared from VEGF siRNA-PEG conjugate and cationic fusogenic peptide.

Lee SH, Kim SH, Park TG.

Biochem Biophys Res Commun. 2007 Jun 1;357(2):511-6. Epub 2007 Apr 9.

PMID:
17434451
15.

Target-specific delivery of siRNA by stabilized calcium phosphate nanoparticles using dopa-hyaluronic acid conjugate.

Lee MS, Lee JE, Byun E, Kim NW, Lee K, Lee H, Sim SJ, Lee DS, Jeong JH.

J Control Release. 2014 Oct 28;192:122-30. doi: 10.1016/j.jconrel.2014.06.049. Epub 2014 Jul 1.

PMID:
24995950
16.
17.

Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy.

Yang XZ, Dou S, Sun TM, Mao CQ, Wang HX, Wang J.

J Control Release. 2011 Dec 10;156(2):203-11. doi: 10.1016/j.jconrel.2011.07.035. Epub 2011 Aug 1.

PMID:
21839126
18.

Suppression of tumor growth by systemic delivery of anti-VEGF siRNA with cell-penetrating peptide-modified MPEG-PCL nanomicelles.

Kanazawa T, Sugawara K, Tanaka K, Horiuchi S, Takashima Y, Okada H.

Eur J Pharm Biopharm. 2012 Aug;81(3):470-7. doi: 10.1016/j.ejpb.2012.04.021. Epub 2012 May 2.

PMID:
22579732
19.

F127/Calcium phosphate hybrid nanoparticles: a promising vector for improving siRNA delivery and gene silencing.

Qin L, Sun Y, Liu P, Wang Q, Han B, Duan Y.

J Biomater Sci Polym Ed. 2013;24(15):1757-66. doi: 10.1080/09205063.2013.801702. Epub 2013 Jun 8.

PMID:
23746331
20.

Smart multilayered assembly for biocompatible siRNA delivery featuring dissolvable silica, endosome-disrupting polycation, and detachable PEG.

Suma T, Miyata K, Anraku Y, Watanabe S, Christie RJ, Takemoto H, Shioyama M, Gouda N, Ishii T, Nishiyama N, Kataoka K.

ACS Nano. 2012 Aug 28;6(8):6693-705. doi: 10.1021/nn301164a. Epub 2012 Aug 8.

PMID:
22835034

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