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Promotion of the induction of cell pluripotency through metabolic remodeling by thyroid hormone triiodothyronine-activated PI3K/AKT signal pathway.

Chen M, Zhang H, Wu J, Xu L, Xu D, Sun J, He Y, Zhou X, Wang Z, Wu L, Xu S, Wang J, Jiang S, Zhou X, Hoffman AR, Hu X, Hu J, Li T.

Biomaterials. 2012 Aug;33(22):5514-23. doi: 10.1016/j.biomaterials.2012.04.001.


A thyroid hormone receptor/KLF9 axis in human hepatocytes and pluripotent stem cells.

Cvoro A, Devito L, Milton FA, Noli L, Zhang A, Filippi C, Sakai K, Suh JH, H Sieglaff D, Dhawan A, Sakai T, Ilic D, Webb P.

Stem Cells. 2015 Feb;33(2):416-28. doi: 10.1002/stem.1875.


Doxycycline enhances survival and self-renewal of human pluripotent stem cells.

Chang MY, Rhee YH, Yi SH, Lee SJ, Kim RK, Kim H, Park CH, Lee SH.

Stem Cell Reports. 2014 Aug 12;3(2):353-64. doi: 10.1016/j.stemcr.2014.06.013.


[Progress on PI3K/Akt signaling pathway regulating self-renewal and pluripotency of embryonic stem cells].

Yin MM, Cui YR, Wang L, Wang JY, Gao Y, Xi JY.

Sheng Li Xue Bao. 2014 Apr 25;66(2):223-30. Review. Chinese.


Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells.

Utikal J, Maherali N, Kulalert W, Hochedlinger K.

J Cell Sci. 2009 Oct 1;122(Pt 19):3502-10. doi: 10.1242/jcs.054783.


Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells.

Watanabe S, Umehara H, Murayama K, Okabe M, Kimura T, Nakano T.

Oncogene. 2006 May 4;25(19):2697-707.


Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation.

Cho HJ, Lee CS, Kwon YW, Paek JS, Lee SH, Hur J, Lee EJ, Roh TY, Chu IS, Leem SH, Kim Y, Kang HJ, Park YB, Kim HS.

Blood. 2010 Jul 22;116(3):386-95. doi: 10.1182/blood-2010-02-269589.


Efficient induction of pluripotent stem cells from menstrual blood.

Li Y, Li X, Zhao H, Feng R, Zhang X, Tai D, An G, Wen J, Tan J.

Stem Cells Dev. 2013 Apr 1;22(7):1147-58. doi: 10.1089/scd.2012.0428.


Reprogramming with defined factors: from induced pluripotency to induced transdifferentiation.

Masip M, Veiga A, Izpisúa Belmonte JC, Simón C.

Mol Hum Reprod. 2010 Nov;16(11):856-68. doi: 10.1093/molehr/gaq059. Review.


Serum starvation induced cell cycle synchronization facilitates human somatic cells reprogramming.

Chen M, Huang J, Yang X, Liu B, Zhang W, Huang L, Deng F, Ma J, Bai Y, Lu R, Huang B, Gao Q, Zhuo Y, Ge J.

PLoS One. 2012;7(4):e28203. doi: 10.1371/journal.pone.0028203.


HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2.

Prigione A, Rohwer N, Hoffmann S, Mlody B, Drews K, Bukowiecki R, Blümlein K, Wanker EE, Ralser M, Cramer T, Adjaye J.

Stem Cells. 2014 Feb;32(2):364-76. doi: 10.1002/stem.1552.


PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading.

Zeller KS, Idevall-Hagren O, Stefansson A, Velling T, Jackson SP, Downward J, Tengholm A, Johansson S.

Cell Signal. 2010 Dec;22(12):1838-48. doi: 10.1016/j.cellsig.2010.07.011. Erratum in: Cell Signal. 2012 Apr;24(4):971-2.


Signaling networks in human pluripotent stem cells.

Dalton S.

Curr Opin Cell Biol. 2013 Apr;25(2):241-6. doi: 10.1016/ Review.


Valproic acid enhances Oct4 promoter activity through PI3K/Akt/mTOR pathway activated nuclear receptors.

Teng HF, Li PN, Hou DR, Liu SW, Lin CT, Loo MR, Kao CH, Lin KH, Chen SL.

Mol Cell Endocrinol. 2014 Mar 5;383(1-2):147-58. doi: 10.1016/j.mce.2013.12.008.


Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.

Kim JB, Zaehres H, Wu G, Gentile L, Ko K, Sebastiano V, Araúzo-Bravo MJ, Ruau D, Han DW, Zenke M, Schöler HR.

Nature. 2008 Jul 31;454(7204):646-50. doi: 10.1038/nature07061.


Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity.

Shack S, Wang XT, Kokkonen GC, Gorospe M, Longo DL, Holbrook NJ.

Mol Cell Biol. 2003 Apr;23(7):2407-14.


n-Butylidenephthalide (BP) maintains stem cell pluripotency by activating Jak2/Stat3 pathway and increases the efficiency of iPS cells generation.

Liu SP, Harn HJ, Chien YJ, Chang CH, Hsu CY, Fu RH, Huang YC, Chen SY, Shyu WC, Lin SZ.

PLoS One. 2012;7(9):e44024. doi: 10.1371/journal.pone.0044024.


Pluripotent reprogramming of fibroblasts by lentiviral mediated insertion of SOX2, C-MYC, and TCL-1A.

Picanço-Castro V, Russo-Carbolante E, Reis LC, Fraga AM, de Magalhães DA, Orellana MD, Panepucci RA, Pereira LV, Covas DT.

Stem Cells Dev. 2011 Jan;20(1):169-80. doi: 10.1089/scd.2009.0424.

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