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Items: 1 to 20 of 87

1.

Tumor promoting effect of podoplanin-positive fibroblasts is mediated by enhanced RhoA activity.

Ito S, Ishii G, Hoshino A, Hashimoto H, Neri S, Kuwata T, Higashi M, Nagai K, Ochiai A.

Biochem Biophys Res Commun. 2012 May 25;422(1):194-9. doi: 10.1016/j.bbrc.2012.04.158. Epub 2012 May 7.

PMID:
22575513
2.

Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma.

Neri S, Ishii G, Hashimoto H, Kuwata T, Nagai K, Date H, Ochiai A.

Int J Cancer. 2015 Aug 15;137(4):784-96. doi: 10.1002/ijc.29464. Epub 2015 Feb 20.

3.

Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation: podoplanin in fibroblast functions for tumor progression.

Hoshino A, Ishii G, Ito T, Aoyagi K, Ohtaki Y, Nagai K, Sasaki H, Ochiai A.

Cancer Res. 2011 Jul 15;71(14):4769-79. doi: 10.1158/0008-5472.CAN-10-3228. Epub 2011 May 24.

4.

Ezrin-expressing lung adenocarcinoma cells and podoplanin-positive fibroblasts form a malignant microenvironment.

Suzuki S, Ishii G, Matsuwaki R, Neri S, Hashimoto H, Yamauchi C, Aokage K, Hishida T, Yoshida J, Kohno M, Nagai K, Ochiai A.

J Cancer Res Clin Oncol. 2015 Mar;141(3):475-84. doi: 10.1007/s00432-014-1851-8. Epub 2014 Oct 11.

PMID:
25304618
5.

Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.

Martín-Villar E, Megías D, Castel S, Yurrita MM, Vilaró S, Quintanilla M.

J Cell Sci. 2006 Nov 1;119(Pt 21):4541-53. Epub 2006 Oct 17.

6.

Podoplanin-expressing cancer-associated fibroblasts inhibit small cell lung cancer growth.

Takahashi A, Ishii G, Neri S, Yoshida T, Hashimoto H, Suzuki S, Umemura S, Matsumoto S, Yoh K, Niho S, Goto K, Ohmatsu H, Nagai K, Gemma A, Ohe Y, Ochiai A.

Oncotarget. 2015 Apr 20;6(11):9531-41.

7.
8.

Integrin alpha 11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cells.

Zhu CQ, Popova SN, Brown ER, Barsyte-Lovejoy D, Navab R, Shih W, Li M, Lu M, Jurisica I, Penn LZ, Gullberg D, Tsao MS.

Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11754-9. Epub 2007 Jun 28.

9.
10.

Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton.

Wicki A, Lehembre F, Wick N, Hantusch B, Kerjaschki D, Christofori G.

Cancer Cell. 2006 Apr;9(4):261-72.

11.

The headpiece domain of dematin regulates cell shape, motility, and wound healing by modulating RhoA activation.

Mohseni M, Chishti AH.

Mol Cell Biol. 2008 Aug;28(15):4712-8. doi: 10.1128/MCB.00237-08. Epub 2008 May 27.

12.

Serines in the intracellular tail of podoplanin (PDPN) regulate cell motility.

Krishnan H, Ochoa-Alvarez JA, Shen Y, Nevel E, Lakshminarayanan M, Williams MC, Ramirez MI, Miller WT, Goldberg GS.

J Biol Chem. 2013 Apr 26;288(17):12215-21. doi: 10.1074/jbc.C112.446823. Epub 2013 Mar 25.

13.

Podoplanin expression identified in stromal fibroblasts as a favorable prognostic marker in patients with colorectal carcinoma.

Yamanashi T, Nakanishi Y, Fujii G, Akishima-Fukasawa Y, Moriya Y, Kanai Y, Watanabe M, Hirohashi S.

Oncology. 2009;77(1):53-62. doi: 10.1159/000226112. Epub 2009 Jun 25.

PMID:
19556810
14.

Podoplanin deficient mice show a RhoA-related hypoplasia of the sinus venosus myocardium including the sinoatrial node.

Mahtab EA, Vicente-Steijn R, Hahurij ND, Jongbloed MR, Wisse LJ, DeRuiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger-de Groot AC.

Dev Dyn. 2009 Jan;238(1):183-93. doi: 10.1002/dvdy.21819.

15.

The role of RhoA in the regulation of cell morphology and motility.

Tkach V, Bock E, Berezin V.

Cell Motil Cytoskeleton. 2005 May;61(1):21-33.

PMID:
15776463
16.

SRC induces podoplanin expression to promote cell migration.

Shen Y, Chen CS, Ichikawa H, Goldberg GS.

J Biol Chem. 2010 Mar 26;285(13):9649-56. doi: 10.1074/jbc.M109.047696. Epub 2010 Feb 1.

17.

Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation.

Takeuchi S, Fukuda K, Yamada T, Arai S, Takagi S, Ishii G, Ochiai A, Iwakiri S, Itoi K, Uehara H, Nishihara H, Fujita N, Yano S.

Cancer Sci. 2017 Apr;108(4):696-703. doi: 10.1111/cas.13190. Epub 2017 Apr 12.

18.

Abrogation of fibroblast activation protein enzymatic activity attenuates tumor growth.

Cheng JD, Valianou M, Canutescu AA, Jaffe EK, Lee HO, Wang H, Lai JH, Bachovchin WW, Weiner LM.

Mol Cancer Ther. 2005 Mar;4(3):351-60.

19.

Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42.

Navarro A, Perez RE, Rezaiekhaligh MH, Mabry SM, Ekekezie II.

Am J Physiol Lung Cell Mol Physiol. 2011 Jan;300(1):L32-42. doi: 10.1152/ajplung.00171.2010. Epub 2010 Oct 29.

20.

Treponema denticola Msp-deduced peptide conjugate, P34BSA, promotes RhoA-dependent actin stress fiber formation independent of its internalization by fibroblasts.

Amin M, Magnusson KE, Kapus A, Glogauer M, Ellen RP.

Cell Motil Cytoskeleton. 2008 May;65(5):406-21. doi: 10.1002/cm.20270. Erratum in: Cell Motil Cytoskeleton. 2008 Jul;65(7):594.

PMID:
18330900

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