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Items: 1 to 20 of 140

1.

Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase.

Gardner CR, Hankey P, Mishin V, Francis M, Yu S, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 Jul 15;262(2):139-48. doi: 10.1016/j.taap.2012.04.027. Epub 2012 May 1.

2.

Exaggerated hepatotoxicity of acetaminophen in mice lacking tumor necrosis factor receptor-1. Potential role of inflammatory mediators.

Gardner CR, Laskin JD, Dambach DM, Chiu H, Durham SK, Zhou P, Bruno M, Gerecke DR, Gordon MK, Laskin DL.

Toxicol Appl Pharmacol. 2003 Oct 15;192(2):119-30.

PMID:
14550746
3.

Role of galectin-3 in classical and alternative macrophage activation in the liver following acetaminophen intoxication.

Dragomir AC, Sun R, Choi H, Laskin JD, Laskin DL.

J Immunol. 2012 Dec 15;189(12):5934-41. doi: 10.4049/jimmunol.1201851. Epub 2012 Nov 21.

4.

Distinct roles of NF-kappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity.

Dambach DM, Durham SK, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2006 Mar 1;211(2):157-65. Epub 2005 Aug 2.

PMID:
16081117
5.

Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production.

Dragomir AC, Sun R, Mishin V, Hall LB, Laskin JD, Laskin DL.

Toxicol Sci. 2012 Jun;127(2):609-19. doi: 10.1093/toxsci/kfs117. Epub 2012 Mar 29.

6.

Role of CCR2 in macrophage migration into the liver during acetaminophen-induced hepatotoxicity in the mouse.

Dambach DM, Watson LM, Gray KR, Durham SK, Laskin DL.

Hepatology. 2002 May;35(5):1093-103.

PMID:
11981759
7.

Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.

Gardner CR, Laskin JD, Dambach DM, Sacco M, Durham SK, Bruno MK, Cohen SD, Gordon MK, Gerecke DR, Zhou P, Laskin DL.

Toxicol Appl Pharmacol. 2002 Oct 1;184(1):27-36.

PMID:
12392966
8.

The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury.

Mandal M, Gardner CR, Sun R, Choi H, Lad S, Mishin V, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2016 Aug 1;304:110-20. doi: 10.1016/j.taap.2016.04.019. Epub 2016 May 7.

PMID:
27163765
9.

Deficiency of interleukin-15 enhances susceptibility to acetaminophen-induced liver injury in mice.

Hou HS, Liao CL, Sytwu HK, Liao NS, Huang TY, Hsieh TY, Chu HC.

PLoS One. 2012;7(9):e44880. doi: 10.1371/journal.pone.0044880. Epub 2012 Sep 18.

10.
11.

Role of nitric oxide in hepatic microvascular injury elicited by acetaminophen in mice.

Ito Y, Abril ER, Bethea NW, McCuskey RS.

Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G60-7. Epub 2003 Sep 11.

12.

The dual role of osteopontin in acetaminophen hepatotoxicity.

He CY, Liang BB, Fan XY, Cao L, Chen R, Guo YJ, Zhao J.

Acta Pharmacol Sin. 2012 Aug;33(8):1004-12. doi: 10.1038/aps.2012.47. Epub 2012 Jun 25.

13.

Distinct roles of tumor necrosis factor-alpha and nitric oxide in acute liver injury induced by carbon tetrachloride in mice.

Morio LA, Chiu H, Sprowles KA, Zhou P, Heck DE, Gordon MK, Laskin DL.

Toxicol Appl Pharmacol. 2001 Apr 1;172(1):44-51.

PMID:
11264022
14.

Role of p55 tumor necrosis factor receptor 1 in acetaminophen-induced antioxidant defense.

Chiu H, Gardner CR, Dambach DM, Brittingham JA, Durham SK, Laskin JD, Laskin DL.

Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G959-66. Epub 2003 Jul 3.

15.

Role of IL-6 in an IL-10 and IL-4 double knockout mouse model uniquely susceptible to acetaminophen-induced liver injury.

Bourdi M, Eiras DP, Holt MP, Webster MR, Reilly TP, Welch KD, Pohl LR.

Chem Res Toxicol. 2007 Feb;20(2):208-16.

PMID:
17305405
16.

Acetaminophen-induced hepatotoxicity.

James LP, Mayeux PR, Hinson JA.

Drug Metab Dispos. 2003 Dec;31(12):1499-506. Review.

17.

Role of STK in mouse liver macrophage and endothelial cell responsiveness during acute endotoxemia.

Laskin DL, Chen L, Hankey PA, Laskin JD.

J Leukoc Biol. 2010 Aug;88(2):373-82. doi: 10.1189/jlb.0210113. Epub 2010 May 7.

18.

Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.

Minamino T, Ito Y, Ohkubo H, Hosono K, Suzuki T, Sato T, Ae T, Shibuya A, Sakagami H, Narumiya S, Koizumi W, Majima M.

Toxicol Appl Pharmacol. 2012 Feb 15;259(1):104-14. doi: 10.1016/j.taap.2011.12.013. Epub 2011 Dec 21.

PMID:
22206755
20.

Complement activation in acetaminophen-induced liver injury in mice.

Singhal R, Ganey PE, Roth RA.

J Pharmacol Exp Ther. 2012 May;341(2):377-85. doi: 10.1124/jpet.111.189837. Epub 2012 Feb 7.

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