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Items: 1 to 20 of 80

1.

Down-regulation of hepatic CYP3A and CYP2C mediated metabolism in rats with moderate chronic kidney disease.

Velenosi TJ, Fu AY, Luo S, Wang H, Urquhart BL.

Drug Metab Dispos. 2012 Aug;40(8):1508-14. doi: 10.1124/dmd.112.045245. Epub 2012 May 9.

2.

Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease.

Velenosi TJ, Feere DA, Sohi G, Hardy DB, Urquhart BL.

FASEB J. 2014 Dec;28(12):5388-97. doi: 10.1096/fj.14-258780. Epub 2014 Sep 10.

3.

Down-regulation of liver drug-metabolizing enzymes in a murine model of chronic renal failure.

Dani M, Boisvert C, Michaud J, Naud J, Lefrançois S, Leblond FA, Pichette V.

Drug Metab Dispos. 2010 Mar;38(3):357-60. doi: 10.1124/dmd.109.029991. Epub 2009 Dec 9.

4.

Short communication: insulin alters hepatic progesterone catabolic enzymes cytochrome P450 2C and 3A in dairy cows.

Lemley CO, Butler ST, Butler WR, Wilson ME.

J Dairy Sci. 2008 Feb;91(2):641-5. doi: 10.3168/jds.2007-0636.

PMID:
18218751
5.

Effect of erythropoietin on hepatic cytochrome P450 expression and function in an adenine-fed rat model of chronic kidney disease.

Feere DA, Velenosi TJ, Urquhart BL.

Br J Pharmacol. 2015 Jan;172(1):201-13. doi: 10.1111/bph.12932. Epub 2014 Nov 24.

6.

Differential alteration of cytochrome P450 isoenzymes in two experimental models of cirrhosis.

Bastien MC, Leblond F, Pichette V, Villeneuve JP.

Can J Physiol Pharmacol. 2000 Nov;78(11):912-9.

PMID:
11100940
7.

Down-regulation of hepatic cytochrome p450 in chronic renal failure: role of uremic mediators.

Guévin C, Michaud J, Naud J, Leblond FA, Pichette V.

Br J Pharmacol. 2002 Dec;137(7):1039-46.

8.

Downregulation of hepatic cytochrome P450 in chronic renal failure.

Leblond F, Guévin C, Demers C, Pellerin I, Gascon-Barré M, Pichette V.

J Am Soc Nephrol. 2001 Feb;12(2):326-32.

9.

Role of temperature on protein and mRNA cytochrome P450 3A (CYP3A) isozymes expression and midazolam oxidation by cultured rat precision-cut liver slices.

Rekka E, Evdokimova E, Eeckhoudt S, Labar G, Calderon PB.

Biochem Pharmacol. 2002 Aug 15;64(4):633-43.

PMID:
12167482
10.
11.

Effects of chronic renal failure on kidney drug transporters and cytochrome P450 in rats.

Naud J, Michaud J, Beauchemin S, Hébert MJ, Roger M, Lefrancois S, Leblond FA, Pichette V.

Drug Metab Dispos. 2011 Aug;39(8):1363-9. doi: 10.1124/dmd.111.039115. Epub 2011 Apr 27.

12.

Differential expression and function of CYP2C isoforms in human intestine and liver.

Läpple F, von Richter O, Fromm MF, Richter T, Thon KP, Wisser H, Griese EU, Eichelbaum M, Kivistö KT.

Pharmacogenetics. 2003 Sep;13(9):565-75.

PMID:
12972955
13.

Soy protein isolate induces CYP3A1 and CYP3A2 in prepubertal rats.

Ronis MJ, Chen Y, Badeaux J, Laurenzana E, Badger TM.

Exp Biol Med (Maywood). 2006 Jan;231(1):60-9.

PMID:
16380645
14.

Renal and hepatic family 3A cytochromes P450 (CYP3A) in spontaneously hypertensive rats.

Ghosh SS, Basu AK, Ghosh S, Hagley R, Kramer L, Schuetz J, Grogan WM, Guzelian P, Watlington CO.

Biochem Pharmacol. 1995 Jun 29;50(1):49-54.

PMID:
7605344
15.

Effects of serum from patients with chronic renal failure on rat hepatic cytochrome P450.

Michaud J, Dubé P, Naud J, Leblond FA, Desbiens K, Bonnardeaux A, Pichette V.

Br J Pharmacol. 2005 Apr;144(8):1067-77.

16.

Head injury and cytochrome P-450 enzymes. Differential effect on mRNA and protein expression in the Fischer-344 rat.

Toler SM, Young AB, McClain CJ, Shedlofsky SI, Bandyopadhyay AM, Blouin RA.

Drug Metab Dispos. 1993 Nov-Dec;21(6):1064-9.

PMID:
7905385
17.

Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure.

Kusaba J, Kajikawa N, Kawasaki H, Kurosaki Y, Aiba T.

Biopharm Drug Dispos. 2012 Jan;33(1):22-9. doi: 10.1002/bdd.1774. Epub 2012 Feb 27.

PMID:
22351566
18.

Selective induction of cytochrome P450 3A1 by dexamethasone in cultured rat hepatocytes: analysis with a novel reverse transcriptase-polymerase chain reaction assay section sign.

Hoen PA, Commandeur JN, Vermeulen NP, Van Berkel TJ, Bijsterbosch MK.

Biochem Pharmacol. 2000 Nov 15;60(10):1509-18.

PMID:
11020454
19.
20.

Effect of androgen administration during puberty on hepatic CYP2C11, CYP3A, and CYP2A1 expression in adult female rats.

Anderson MD, Bandiera SM, Chang TK, Bellward GD.

Drug Metab Dispos. 1998 Oct;26(10):1031-8.

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