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EGFR exon 19 in-frame deletion and polymorphisms of DNA repair genes in never-smoking female lung adenocarcinoma patients.

Yang SY, Yang TY, Li YJ, Chen KC, Liao KM, Hsu KH, Tsai CR, Chen CY, Hsu CP, Hsia JY, Chuang CY, Tsai YH, Chen KY, Huang MS, Su WC, Chen YM, Hsiung CA, Shen CY, Chang GC, Yang PC, Chen CJ.

Int J Cancer. 2013 Jan 15;132(2):449-58. doi: 10.1002/ijc.27630. Epub 2012 Jun 28.


EGFR L858R mutation and polymorphisms of genes related to estrogen biosynthesis and metabolism in never-smoking female lung adenocarcinoma patients.

Yang SY, Yang TY, Chen KC, Li YJ, Hsu KH, Tsai CR, Chen CY, Hsu CP, Hsia JY, Chuang CY, Tsai YH, Chen KY, Huang MS, Su WC, Chen YM, Hsiung CA, Shen CY, Chang GC, Yang PC, Chen CJ.

Clin Cancer Res. 2011 Apr 15;17(8):2149-58. doi: 10.1158/1078-0432.CCR-10-2045. Epub 2011 Feb 7.


The impact of sex and smoking status on the mutational spectrum of epidermal growth factor receptor gene in non small cell lung cancer.

Toyooka S, Matsuo K, Shigematsu H, Kosaka T, Tokumo M, Yatabe Y, Ichihara S, Inukai M, Suehisa H, Soh J, Kiura K, Fong KM, Lee H, Wistuba II, Gazdar AF, Mitsudomi T, Date H.

Clin Cancer Res. 2007 Oct 1;13(19):5763-8.


EGFR polymorphisms, hormone replacement therapy and lung adenocarcinoma risk: analysis from a genome-wide association study in never-smoking women.

Chen KY, Hsiao CF, Chang GC, Tsai YH, Su WC, Chen YM, Huang MS, Hsiung CA, Chen CJ, Yang PC; GELAC Study Group..

Carcinogenesis. 2013 Mar;34(3):612-9. doi: 10.1093/carcin/bgs385. Epub 2012 Dec 13. Erratum in: Carcinogenesis. 2013 Jun;34(6):1412.


Impact of cigarette smoking on response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in lung adenocarcinoma with activating EGFR mutations.

Kim MH, Kim HR, Cho BC, Bae MK, Kim EY, Lee CY, Lee JS, Kang DR, Kim JH.

Lung Cancer. 2014 May;84(2):196-202. doi: 10.1016/j.lungcan.2014.01.022. Epub 2014 Feb 3.


Polymorphisms of MLH1 and MSH2 genes and the risk of lung cancer among never smokers.

Lo YL, Hsiao CF, Jou YS, Chang GC, Tsai YH, Su WC, Chen KY, Chen YM, Huang MS, Hsieh WS, Chen CJ, Hsiung CA.

Lung Cancer. 2011 Jun;72(3):280-6. doi: 10.1016/j.lungcan.2010.10.009. Epub 2010 Nov 19.


The XPD variant alleles are associated with increased aromatic DNA adduct level and lung cancer risk.

Hou SM, Fält S, Angelini S, Yang K, Nyberg F, Lambert B, Hemminki K.

Carcinogenesis. 2002 Apr;23(4):599-603.


Impact of age on epidermal growth factor receptor mutation in lung cancer.

Ueno T, Toyooka S, Suda K, Soh J, Yatabe Y, Miyoshi S, Matsuo K, Mitsudomi T.

Lung Cancer. 2012 Dec;78(3):207-11. doi: 10.1016/j.lungcan.2012.09.006. Epub 2012 Oct 2.


Association of an EGFR intron 1 SNP with never-smoking female lung adenocarcinoma patients.

Jou YS, Lo YL, Hsiao CF, Chang GC, Tsai YH, Su WC, Chen YM, Huang MS, Chen HL, Chen CJ, Yang PC, Hsiung CA.

Lung Cancer. 2009 Jun;64(3):251-6. doi: 10.1016/j.lungcan.2008.09.014. Epub 2008 Nov 20.


Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis.

Zhang Y, Sun Y, Pan Y, Li C, Shen L, Li Y, Luo X, Ye T, Wang R, Hu H, Li H, Wang L, Pao W, Chen H.

Clin Cancer Res. 2012 Apr 1;18(7):1947-53. doi: 10.1158/1078-0432.CCR-11-2511. Epub 2012 Feb 8.


Mutations within the tyrosine kinase domain of EGFR gene specifically occur in lung adenocarcinoma patients with a low exposure of tobacco smoking.

Sugio K, Uramoto H, Ono K, Oyama T, Hanagiri T, Sugaya M, Ichiki Y, So T, Nakata S, Morita M, Yasumoto K.

Br J Cancer. 2006 Mar 27;94(6):896-903.


Mutation and polymorphism in the EGFR-TK domain associated with lung cancer.

Zhang W, Stabile LP, Keohavong P, Romkes M, Grandis JR, Traynor AM, Siegfried JM.

J Thorac Oncol. 2006 Sep;1(7):635-47.


Association of genetic polymorphisms in DNA repair pathway genes with non-small cell lung cancer risk.

Qian B, Zhang H, Zhang L, Zhou X, Yu H, Chen K.

Lung Cancer. 2011 Aug;73(2):138-46. doi: 10.1016/j.lungcan.2010.11.018. Epub 2010 Dec 30.


Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas.

D'Angelo SP, Pietanza MC, Johnson ML, Riely GJ, Miller VA, Sima CS, Zakowski MF, Rusch VW, Ladanyi M, Kris MG.

J Clin Oncol. 2011 May 20;29(15):2066-70. doi: 10.1200/JCO.2010.32.6181. Epub 2011 Apr 11.


[Detection of epidermal growth factor receptor mutations in non-small cell lung cancer by real-time PCR using TaqMan-MGB probes].

Zhou CC, Zhou SW, Pan H, Su B, Gao ZQ.

Zhonghua Zhong Liu Za Zhi. 2007 Feb;29(2):119-23. Chinese.


[EGFR gene mutation status among lung cancer patients in China].

Li Q, Zhao YL, Hao HJ, Li XH.

Zhonghua Zhong Liu Za Zhi. 2007 Apr;29(4):270-3. Chinese.


Association between polymorphisms in DNA repair genes and survival of non-smoking female patients with lung adenocarcinoma.

Yin Z, Zhou B, He Q, Li M, Guan P, Li X, Cui Z, Xue X, Su M, Ma R, Bai W, Xia S, Jiang Y, Xu S, Lv Y, Li X.

BMC Cancer. 2009 Dec 15;9:439. doi: 10.1186/1471-2407-9-439.


Gene-environment interactions between the smoking habit and polymorphisms in the DNA repair genes, APE1 Asp148Glu and XRCC1 Arg399Gln, in Japanese lung cancer risk.

Ito H, Matsuo K, Hamajima N, Mitsudomi T, Sugiura T, Saito T, Yasue T, Lee KM, Kang D, Yoo KY, Sato S, Ueda R, Tajima K.

Carcinogenesis. 2004 Aug;25(8):1395-401. Epub 2004 Mar 25.


[Mutations in exon 19 of EGFR gene in non-small cell lung cancer from Chinese patients].

Wang HY, Luo H, Zhao YM, Tang L, Zhou CC.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008 Jun;25(3):315-8. Chinese.


Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma.

Ren S, Chen X, Kuang P, Zheng L, Su C, Li J, Li B, Wang Y, Liu L, Hu Q, Zhang J, Tang L, Li X, Zhou C, Schmid-Bindert G.

Cancer. 2012 Nov 15;118(22):5588-94. doi: 10.1002/cncr.27603. Epub 2012 May 8.

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