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Items: 1 to 20 of 94

1.

Mechanism of BAG1 repair on Parkinson's disease-linked DJ1 mutation.

Chen CY.

J Biomol Struct Dyn. 2012;30(1):1-12. doi: 10.1080/07391102.2012.674182.

PMID:
22571429
2.

Molecular basis for the structural instability of human DJ-1 induced by the L166P mutation associated with Parkinson's disease.

Anderson PC, Daggett V.

Biochemistry. 2008 Sep 9;47(36):9380-93. doi: 10.1021/bi800677k. Epub 2008 Aug 16.

3.

BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.

Deeg S, Gralle M, Sroka K, Bähr M, Wouters FS, Kermer P.

J Cell Biol. 2010 Feb 22;188(4):505-13. doi: 10.1083/jcb.200904103. Epub 2010 Feb 15.

4.

Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease.

Tao X, Tong L.

J Biol Chem. 2003 Aug 15;278(33):31372-9. Epub 2003 May 21.

5.

Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).

Hering R, Strauss KM, Tao X, Bauer A, Woitalla D, Mietz EM, Petrovic S, Bauer P, Schaible W, Müller T, Schöls L, Klein C, Berg D, Meyer PT, Schulz JB, Wollnik B, Tong L, Krüger R, Riess O.

Hum Mutat. 2004 Oct;24(4):321-9.

PMID:
15365989
6.

Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells.

Repici M, Straatman KR, Balduccio N, Enguita FJ, Outeiro TF, Giorgini F.

J Mol Med (Berl). 2013 May;91(5):599-611. doi: 10.1007/s00109-012-0976-y. Epub 2012 Nov 27.

7.

Destabilization of DJ-1 by familial substitution and oxidative modifications: implications for Parkinson's disease.

Hulleman JD, Mirzaei H, Guigard E, Taylor KL, Ray SS, Kay CM, Regnier FE, Rochet JC.

Biochemistry. 2007 May 15;46(19):5776-89. Epub 2007 Apr 24.

PMID:
17451229
8.

Structural effects of Parkinson's disease linked DJ-1 mutations.

Malgieri G, Eliezer D.

Protein Sci. 2008 May;17(5):855-68. doi: 10.1110/ps.073411608.

9.

Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.

Alvarez-Castelao B, Muñoz C, Sánchez I, Goethals M, Vandekerckhove J, Castaño JG.

Biochim Biophys Acta. 2012 Feb;1823(2):524-33. doi: 10.1016/j.bbamcr.2011.11.010. Epub 2011 Dec 8.

10.

Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6.

Vilotti S, Codrich M, Dal Ferro M, Pinto M, Ferrer I, Collavin L, Gustincich S, Zucchelli S.

PLoS One. 2012;7(4):e35051. doi: 10.1371/journal.pone.0035051. Epub 2012 Apr 20.

11.

Crystal structure of DJ-1/RS and implication on familial Parkinson's disease.

Huai Q, Sun Y, Wang H, Chin LS, Li L, Robinson H, Ke H.

FEBS Lett. 2003 Aug 14;549(1-3):171-5.

12.

Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.

Görner K, Holtorf E, Odoy S, Nuscher B, Yamamoto A, Regula JT, Beyer K, Haass C, Kahle PJ.

J Biol Chem. 2004 Feb 20;279(8):6943-51. Epub 2003 Nov 7.

13.

Loss of function of DJ-1 triggered by Parkinson's disease-associated mutation is due to proteolytic resistance to caspase-6.

Giaime E, Sunyach C, Druon C, Scarzello S, Robert G, Grosso S, Auberger P, Goldberg MS, Shen J, Heutink P, Pouysségur J, Pagès G, Checler F, Alves da Costa C.

Cell Death Differ. 2010 Jan;17(1):158-69. doi: 10.1038/cdd.2009.116.

14.

ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1.

Duplan E, Giaime E, Viotti J, Sévalle J, Corti O, Brice A, Ariga H, Qi L, Checler F, Alves da Costa C.

J Cell Sci. 2013 May 1;126(Pt 9):2124-33. doi: 10.1242/jcs.127340. Epub 2013 Feb 27.

15.

Dissection of the dimerization modes in the DJ-1 superfamily.

Jung HJ, Kim S, Kim YJ, Kim MK, Kang SG, Lee JH, Kim W, Cha SS.

Mol Cells. 2012 Feb;33(2):163-71. doi: 10.1007/s10059-012-2220-6. Epub 2012 Jan 2.

16.

The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease.

Honbou K, Suzuki NN, Horiuchi M, Niki T, Taira T, Ariga H, Inagaki F.

J Biol Chem. 2003 Aug 15;278(33):31380-4. Epub 2003 Jun 8.

17.

Clinical genetics of Parkinson's disease and related disorders.

Wider C, Wszolek ZK.

Parkinsonism Relat Disord. 2007;13 Suppl 3:S229-32. doi: 10.1016/S1353-8020(08)70007-5. Review.

PMID:
18267241
18.

Structure of Cu(I)-bound DJ-1 reveals a biscysteinate metal binding site at the homodimer interface: insights into mutational inactivation of DJ-1 in Parkinsonism.

Puno MR, Patel NA, Møller SG, Robinson CV, Moody PC, Odell M.

J Am Chem Soc. 2013 Oct 30;135(43):15974-7. doi: 10.1021/ja406010m. Epub 2013 Oct 21.

PMID:
24144264
19.

DJ-1: a newcomer in Parkinson's disease pathology.

da Costa CA.

Curr Mol Med. 2007 Nov;7(7):650-7. Review.

PMID:
18045143
20.

Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1.

Görner K, Holtorf E, Waak J, Pham TT, Vogt-Weisenhorn DM, Wurst W, Haass C, Kahle PJ.

J Biol Chem. 2007 May 4;282(18):13680-91. Epub 2007 Mar 1.

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