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Items: 1 to 20 of 136

1.

Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1.

Gloor JW, Balakrishnan L, Campbell JL, Bambara RA.

Nucleic Acids Res. 2012 Aug;40(14):6774-86. doi: 10.1093/nar/gks388. Epub 2012 May 7.

2.

Flap endonuclease disengages Dna2 helicase/nuclease from Okazaki fragment flaps.

Stewart JA, Campbell JL, Bambara RA.

J Biol Chem. 2006 Dec 15;281(50):38565-72. Epub 2006 Oct 11.

3.

Significance of the dissociation of Dna2 by flap endonuclease 1 to Okazaki fragment processing in Saccharomyces cerevisiae.

Stewart JA, Campbell JL, Bambara RA.

J Biol Chem. 2009 Mar 27;284(13):8283-91. doi: 10.1074/jbc.M809189200. Epub 2009 Jan 29.

4.

Dynamic removal of replication protein A by Dna2 facilitates primer cleavage during Okazaki fragment processing in Saccharomyces cerevisiae.

Stewart JA, Miller AS, Campbell JL, Bambara RA.

J Biol Chem. 2008 Nov 14;283(46):31356-65. doi: 10.1074/jbc.M805965200. Epub 2008 Sep 17.

5.

Pif1 helicase directs eukaryotic Okazaki fragments toward the two-nuclease cleavage pathway for primer removal.

Rossi ML, Pike JE, Wang W, Burgers PM, Campbell JL, Bambara RA.

J Biol Chem. 2008 Oct 10;283(41):27483-93. doi: 10.1074/jbc.M804550200. Epub 2008 Aug 9.

6.

Reconstituted Okazaki fragment processing indicates two pathways of primer removal.

Rossi ML, Bambara RA.

J Biol Chem. 2006 Sep 8;281(36):26051-61. Epub 2006 Jul 11.

7.

The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication.

Levikova M, Cejka P.

Nucleic Acids Res. 2015 Sep 18;43(16):7888-97. doi: 10.1093/nar/gkv710. Epub 2015 Jul 14.

8.

Dynamics of enzymatic interactions during short flap human Okazaki fragment processing by two forms of human DNA polymerase δ.

Lin SH, Wang X, Zhang S, Zhang Z, Lee EY, Lee MY.

DNA Repair (Amst). 2013 Nov;12(11):922-35. doi: 10.1016/j.dnarep.2013.08.008. Epub 2013 Sep 10.

9.

Acetylation of Dna2 endonuclease/helicase and flap endonuclease 1 by p300 promotes DNA stability by creating long flap intermediates.

Balakrishnan L, Stewart J, Polaczek P, Campbell JL, Bambara RA.

J Biol Chem. 2010 Feb 12;285(7):4398-404. doi: 10.1074/jbc.M109.086397. Epub 2009 Dec 17.

10.

Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.

Kao HI, Campbell JL, Bambara RA.

J Biol Chem. 2004 Dec 3;279(49):50840-9. Epub 2004 Sep 22.

11.

Flap endonuclease 1: a central component of DNA metabolism.

Liu Y, Kao HI, Bambara RA.

Annu Rev Biochem. 2004;73:589-615. Review.

PMID:
15189154
12.

Pif1 helicase lengthens some Okazaki fragment flaps necessitating Dna2 nuclease/helicase action in the two-nuclease processing pathway.

Pike JE, Burgers PM, Campbell JL, Bambara RA.

J Biol Chem. 2009 Sep 11;284(37):25170-80. doi: 10.1074/jbc.M109.023325. Epub 2009 Jul 15.

13.

An alternative pathway for Okazaki fragment processing: resolution of fold-back flaps by Pif1 helicase.

Pike JE, Henry RA, Burgers PM, Campbell JL, Bambara RA.

J Biol Chem. 2010 Dec 31;285(53):41712-23. doi: 10.1074/jbc.M110.146894. Epub 2010 Oct 19.

14.

Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates.

Stewart JA, Campbell JL, Bambara RA.

Nucleic Acids Res. 2010 Jan;38(3):920-30. doi: 10.1093/nar/gkp1055. Epub 2009 Nov 24.

15.

Isolation of human Dna2 endonuclease and characterization of its enzymatic properties.

Kim JH, Kim HD, Ryu GH, Kim DH, Hurwitz J, Seo YS.

Nucleic Acids Res. 2006 Apr 4;34(6):1854-64. Print 2006.

16.

Components of the secondary pathway stimulate the primary pathway of eukaryotic Okazaki fragment processing.

Henry RA, Balakrishnan L, Ying-Lin ST, Campbell JL, Bambara RA.

J Biol Chem. 2010 Sep 10;285(37):28496-505. doi: 10.1074/jbc.M110.131870. Epub 2010 Jul 13.

17.

On the roles of Saccharomyces cerevisiae Dna2p and Flap endonuclease 1 in Okazaki fragment processing.

Kao HI, Veeraraghavan J, Polaczek P, Campbell JL, Bambara RA.

J Biol Chem. 2004 Apr 9;279(15):15014-24. Epub 2004 Jan 26.

19.

Okazaki fragment maturation in yeast. I. Distribution of functions between FEN1 AND DNA2.

Ayyagari R, Gomes XV, Gordenin DA, Burgers PM.

J Biol Chem. 2003 Jan 17;278(3):1618-25. Epub 2002 Nov 6.

20.

Flap endonuclease 1.

Balakrishnan L, Bambara RA.

Annu Rev Biochem. 2013;82:119-38. doi: 10.1146/annurev-biochem-072511-122603. Epub 2013 Feb 28. Review.

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