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Items: 1 to 20 of 115

1.

Role of PI3Kα and sarcolemmal ATP-sensitive potassium channels in epoxyeicosatrienoic acid mediated cardioprotection.

Batchu SN, Chaudhary KR, El-Sikhry H, Yang W, Light PE, Oudit GY, Seubert JM.

J Mol Cell Cardiol. 2012 Jul;53(1):43-52. doi: 10.1016/j.yjmcc.2012.04.008. Epub 2012 Apr 27.

PMID:
22561102
2.

Cardioprotective effect of a dual acting epoxyeicosatrienoic acid analogue towards ischaemia reperfusion injury.

Batchu SN, Lee SB, Qadhi RS, Chaudhary KR, El-Sikhry H, Kodela R, Falck JR, Seubert JM.

Br J Pharmacol. 2011 Feb;162(4):897-907. doi: 10.1111/j.1476-5381.2010.01093.x.

3.

Role of B-type natriuretic peptide in epoxyeicosatrienoic acid-mediated improved post-ischaemic recovery of heart contractile function.

Chaudhary KR, Batchu SN, Das D, Suresh MR, Falck JR, Graves JP, Zeldin DC, Seubert JM.

Cardiovasc Res. 2009 Jul 15;83(2):362-70. doi: 10.1093/cvr/cvp134. Epub 2009 Apr 28.

4.

Novel soluble epoxide hydrolase inhibitor protects mitochondrial function following stress.

Batchu SN, Lee SB, Samokhvalov V, Chaudhary KR, El-Sikhry H, Weldon SM, Seubert JM.

Can J Physiol Pharmacol. 2012 Jun;90(6):811-23. doi: 10.1139/y2012-082. Epub 2012 May 24.

PMID:
22624559
5.

Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells.

Katragadda D, Batchu SN, Cho WJ, Chaudhary KR, Falck JR, Seubert JM.

J Mol Cell Cardiol. 2009 Jun;46(6):867-75. doi: 10.1016/j.yjmcc.2009.02.028. Epub 2009 Mar 12.

PMID:
19285984
6.

Epoxyeicosatrienoic acids in cardioprotection: ischemic versus reperfusion injury.

Nithipatikom K, Moore JM, Isbell MA, Falck JR, Gross GJ.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H537-42. Epub 2006 Feb 10.

PMID:
16473964
7.

Protective actions of epoxyeicosatrienoic acid: dual targeting of cardiovascular PI3K and KATP channels.

Bodiga S, Zhang R, Jacobs DE, Larsen BT, Tampo A, Manthati VL, Kwok WM, Zeldin DC, Falck JR, Gutterman DD, Jacobs ER, Medhora MM.

J Mol Cell Cardiol. 2009 Jun;46(6):978-88. doi: 10.1016/j.yjmcc.2009.01.009.

8.
9.

Cytochrome P450 2J3/epoxyeicosatrienoic acids mediate the cardioprotection induced by ischaemic post-conditioning, but not preconditioning, in the rat.

Yu GG, Zeng XJ, Wang HX, Lu LQ, Zheng SP, Ma LQ, Chang J, Wang J, Zhang DM, Du FH, Zhang LK.

Clin Exp Pharmacol Physiol. 2011 Jan;38(1):63-70. doi: 10.1111/j.1440-1681.2010.05464.x.

PMID:
21105892
10.

Early opening of sarcolemmal ATP-sensitive potassium channels is not a key step in PKC-mediated cardioprotection.

Brennan S, Jackson R, Patel M, Sims MW, Hudman D, Norman RI, Lodwick D, Rainbow RD.

J Mol Cell Cardiol. 2015 Feb;79:42-53. doi: 10.1016/j.yjmcc.2014.10.016. Epub 2014 Nov 6.

PMID:
25450614
11.

Cardiac and vascular KATP channels in rats are activated by endogenous epoxyeicosatrienoic acids through different mechanisms.

Lu T, Ye D, Wang X, Seubert JM, Graves JP, Bradbury JA, Zeldin DC, Lee HC.

J Physiol. 2006 Sep 1;575(Pt 2):627-44. Epub 2006 Jun 22.

12.

The protective effect of epoxyeicosatrienoic acids on cerebral ischemia/reperfusion injury is associated with PI3K/Akt pathway and ATP-sensitive potassium channels.

Qu YY, Yuan MY, Liu Y, Xiao XJ, Zhu YL.

Neurochem Res. 2015 Jan;40(1):1-14. doi: 10.1007/s11064-014-1456-2. Epub 2014 Nov 4. Erratum in: Neurochem Res. 2015 Apr;40(4):874.

PMID:
25366463
13.

Epoxyeicosatrienoic acids protect cardiac cells during starvation by modulating an autophagic response.

Samokhvalov V, Alsaleh N, El-Sikhry HE, Jamieson KL, Chen CB, Lopaschuk DG, Carter C, Light PE, Manne R, Falck JR, Seubert JM.

Cell Death Dis. 2013 Oct 24;4:e885. doi: 10.1038/cddis.2013.418.

14.

Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.

Suzuki M, Saito T, Sato T, Tamagawa M, Miki T, Seino S, Nakaya H.

Circulation. 2003 Feb 11;107(5):682-5.

15.

The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel.

Wan TC, Ge ZD, Tampo A, Mio Y, Bienengraeber MW, Tracey WR, Gross GJ, Kwok WM, Auchampach JA.

J Pharmacol Exp Ther. 2008 Jan;324(1):234-43. Epub 2007 Sep 28.

16.

Enhanced postischemic functional recovery in CYP2J2 transgenic hearts involves mitochondrial ATP-sensitive K+ channels and p42/p44 MAPK pathway.

Seubert J, Yang B, Bradbury JA, Graves J, Degraff LM, Gabel S, Gooch R, Foley J, Newman J, Mao L, Rockman HA, Hammock BD, Murphy E, Zeldin DC.

Circ Res. 2004 Sep 3;95(5):506-14. Epub 2004 Jul 15.

17.

Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes.

Lu T, Hoshi T, Weintraub NL, Spector AA, Lee HC.

J Physiol. 2001 Dec 15;537(Pt 3):811-27.

18.

Effect of ischemia reperfusion injury and epoxyeicosatrienoic acids on caveolin expression in mouse myocardium.

Chaudhary KR, Cho WJ, Yang F, Samokhvalov V, El-Sikhry HE, Daniel EE, Seubert JM.

J Cardiovasc Pharmacol. 2013 Mar;61(3):258-63. doi: 10.1097/FJC.0b013e31827afcee.

PMID:
23403888
19.

Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart.

Gross GJ, Gauthier KM, Moore J, Falck JR, Hammock BD, Campbell WB, Nithipatikom K.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2838-44. doi: 10.1152/ajpheart.00186.2008. Epub 2008 Apr 25.

20.

Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts.

Gross GJ, Hsu A, Falck JR, Nithipatikom K.

J Mol Cell Cardiol. 2007 Mar;42(3):687-91. Epub 2007 Jan 10.

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