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Items: 1 to 20 of 182

1.

Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.

Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G.

PLoS One. 2012;7(4):e35497. doi: 10.1371/journal.pone.0035497. Epub 2012 Apr 27.

2.

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.

Shultz LD, Lyons BL, Burzenski LM, Gott B, Chen X, Chaleff S, Kotb M, Gillies SD, King M, Mangada J, Greiner DL, Handgretinger R.

J Immunol. 2005 May 15;174(10):6477-89.

3.

Co-transplantation of human fetal thymus, bone and CD34(+) cells into young adult immunodeficient NOD/SCID IL2Rγ(null) mice optimizes humanized mice that mount adaptive antibody responses.

Chung YS, Son JK, Choi B, Joo SY, Lee YS, Park JB, Moon H, Kim TJ, Kim SH, Hong S, Chang J, Kang MS, Kim SJ.

Clin Immunol. 2015 Apr;157(2):156-65. doi: 10.1016/j.clim.2015.02.005. Epub 2015 Feb 25.

PMID:
25725428
4.

Intrinsic bias and public rearrangements in the human immunoglobulin Vλ light chain repertoire.

Hoi KH, Ippolito GC.

Genes Immun. 2013 Jun;14(4):271-6. doi: 10.1038/gene.2013.10. Epub 2013 Mar 28.

PMID:
23535864
5.

Transplantation of human spleen into immunodeficient NOD/SCID IL2Rγ(null) mice generates humanized mice that improve functional B cell development.

Chung YS, Son JK, Choi B, Park JB, Chang J, Kim SJ.

Clin Immunol. 2015 Dec;161(2):308-15. doi: 10.1016/j.clim.2015.09.001. Epub 2015 Sep 7.

PMID:
26360254
6.

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.

Ishikawa F, Yasukawa M, Lyons B, Yoshida S, Miyamoto T, Yoshimoto G, Watanabe T, Akashi K, Shultz LD, Harada M.

Blood. 2005 Sep 1;106(5):1565-73. Epub 2005 May 26.

7.

Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

Joo SY, Chung YS, Choi B, Kim M, Kim JH, Jun TG, Chang J, Sprent J, Surh CD, Joh JW, Kim SJ.

Transplantation. 2012 Dec 15;94(11):1095-102. doi: 10.1097/TP.0b013e318270f392.

PMID:
23222735
8.

Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

Brehm MA, Cuthbert A, Yang C, Miller DM, DiIorio P, Laning J, Burzenski L, Gott B, Foreman O, Kavirayani A, Herlihy M, Rossini AA, Shultz LD, Greiner DL.

Clin Immunol. 2010 Apr;135(1):84-98. doi: 10.1016/j.clim.2009.12.008. Epub 2010 Jan 21.

9.

Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.

Shultz LD, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, Doi T, Sone A, Suzuki N, Fujiwara H, Yasukawa M, Ishikawa F.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13022-7. doi: 10.1073/pnas.1000475107. Epub 2010 Jul 6.

10.

Hematopoietic stem cell-engrafted NOD/SCID/IL2Rgamma null mice develop human lymphoid systems and induce long-lasting HIV-1 infection with specific humoral immune responses.

Watanabe S, Terashima K, Ohta S, Horibata S, Yajima M, Shiozawa Y, Dewan MZ, Yu Z, Ito M, Morio T, Shimizu N, Honda M, Yamamoto N.

Blood. 2007 Jan 1;109(1):212-8. Epub 2006 Sep 5.

11.

Human B cell development and antibody production in humanized NOD/SCID/IL-2Rγ(null) (NSG) mice conditioned by busulfan.

Choi B, Chun E, Kim M, Kim ST, Yoon K, Lee KY, Kim SJ.

J Clin Immunol. 2011 Apr;31(2):253-64. doi: 10.1007/s10875-010-9478-2. Epub 2010 Oct 28.

PMID:
20981478
12.

Reconstitution of functional human B lymphocytes in NOD/SCID mice engrafted with ex vivo expanded CD34(+) cord blood cells.

Li C, Ando K, Kametani Y, Oki M, Hagihara M, Shimamura K, Habu S, Kato S, Hotta T.

Exp Hematol. 2002 Sep;30(9):1036-43.

PMID:
12225795
13.

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL.

Clin Immunol. 2008 Mar;126(3):303-14. Epub 2007 Dec 21.

PMID:
18096436
14.
15.

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.

Shultz LD, Schweitzer PA, Christianson SW, Gott B, Schweitzer IB, Tennent B, McKenna S, Mobraaten L, Rajan TV, Greiner DL, et al.

J Immunol. 1995 Jan 1;154(1):180-91.

PMID:
7995938
16.

Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.

Pearson T, Shultz LD, Miller D, King M, Laning J, Fodor W, Cuthbert A, Burzenski L, Gott B, Lyons B, Foreman O, Rossini AA, Greiner DL.

Clin Exp Immunol. 2008 Nov;154(2):270-84. doi: 10.1111/j.1365-2249.2008.03753.x. Epub 2008 Sep 8.

17.

NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.

Ito M, Kobayashi K, Nakahata T.

Curr Top Microbiol Immunol. 2008;324:53-76. Review.

PMID:
18481452
18.

Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.

Giassi LJ, Pearson T, Shultz LD, Laning J, Biber K, Kraus M, Woda BA, Schmidt MR, Woodland RT, Rossini AA, Greiner DL.

Exp Biol Med (Maywood). 2008 Aug;233(8):997-1012. doi: 10.3181/0802-RM-70.

19.

Generation of transgenic mice on an NOD/SCID background using the conventional microinjection technique.

Kumagai K, Kubota N, Saito TI, Sasako T, Takizawa R, Sudo K, Kurokawa M, Kadowaki T.

Biol Reprod. 2011 Apr;84(4):682-8. doi: 10.1095/biolreprod.110.087106. Epub 2010 Dec 8.

PMID:
21148106
20.

Co-transplantation of fetal bone tissue facilitates the development and reconstitution in human B cells in humanized NOD/SCID/IL-2Rγnull (NSG) mice.

Kim M, Choi B, Kim SY, Yang JH, Roh CR, Lee KY, Kim SJ.

J Clin Immunol. 2011 Aug;31(4):699-709. doi: 10.1007/s10875-011-9538-2. Epub 2011 May 5.

PMID:
21544592

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