Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

A novel therapeutic approach to treating obesity through modulation of TGFβ signaling.

Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, Kumar R, Grinberg AV, Liharska K, Ucran JA, Howard E, Spiegelman BM, Seehra J, Lachey J.

Endocrinology. 2012 Jul;153(7):3133-46. doi: 10.1210/en.2012-1016. Epub 2012 May 1.

2.

Fat news: A novel ActRIIB decoy receptor in the BAT-tle for obesity.

Bielohuby M.

Endocrinology. 2012 Jul;153(7):2939-41. doi: 10.1210/en.2012-1465. No abstract available.

PMID:
22730280
3.
4.

Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism.

Fournier B, Murray B, Gutzwiller S, Marcaletti S, Marcellin D, Bergling S, Brachat S, Persohn E, Pierrel E, Bombard F, Hatakeyama S, Trendelenburg AU, Morvan F, Richardson B, Glass DJ, Lach-Trifilieff E, Feige JN.

Mol Cell Biol. 2012 Jul;32(14):2871-9. doi: 10.1128/MCB.06575-11. Epub 2012 May 14.

5.

Gene expression profiling of skeletal muscles treated with a soluble activin type IIB receptor.

Rahimov F, King OD, Warsing LC, Powell RE, Emerson CP Jr, Kunkel LM, Wagner KR.

Physiol Genomics. 2011 Apr 27;43(8):398-407. doi: 10.1152/physiolgenomics.00223.2010. Epub 2011 Jan 25.

6.
7.

A soluble activin receptor type IIb prevents the effects of androgen deprivation on body composition and bone health.

Koncarevic A, Cornwall-Brady M, Pullen A, Davies M, Sako D, Liu J, Kumar R, Tomkinson K, Baker T, Umiker B, Monnell T, Grinberg AV, Liharska K, Underwood KW, Ucran JA, Howard E, Barberio J, Spaits M, Pearsall S, Seehra J, Lachey J.

Endocrinology. 2010 Sep;151(9):4289-300. doi: 10.1210/en.2010-0134. Epub 2010 Jun 23.

PMID:
20573726
8.

Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice.

Allen DL, Cleary AS, Speaker KJ, Lindsay SF, Uyenishi J, Reed JM, Madden MC, Mehan RS.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E918-27. doi: 10.1152/ajpendo.00798.2007. Epub 2008 Mar 11.

9.
10.

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure.

Tseng YH, Kokkotou E, Schulz TJ, Huang TL, Winnay JN, Taniguchi CM, Tran TT, Suzuki R, Espinoza DO, Yamamoto Y, Ahrens MJ, Dudley AT, Norris AW, Kulkarni RN, Kahn CR.

Nature. 2008 Aug 21;454(7207):1000-4. doi: 10.1038/nature07221.

11.

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity.

Akpan I, Goncalves MD, Dhir R, Yin X, Pistilli EE, Bogdanovich S, Khurana TS, Ucran J, Lachey J, Ahima RS.

Int J Obes (Lond). 2009 Nov;33(11):1265-73. doi: 10.1038/ijo.2009.162. Epub 2009 Aug 11.

12.

Pretreatment with a soluble activin type IIB receptor/Fc fusion protein improves hypoxia-induced muscle dysfunction.

Pistilli EE, Bogdanovich S, Mosqueira M, Lachey J, Seehra J, Khurana TS.

Am J Physiol Regul Integr Comp Physiol. 2010 Jan;298(1):R96-R103. doi: 10.1152/ajpregu.00138.2009. Epub 2009 Oct 28.

13.

Butyrate improves insulin sensitivity and increases energy expenditure in mice.

Gao Z, Yin J, Zhang J, Ward RE, Martin RJ, Lefevre M, Cefalu WT, Ye J.

Diabetes. 2009 Jul;58(7):1509-17. doi: 10.2337/db08-1637. Epub 2009 Apr 14.

15.

Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents.

Chiu CS, Peekhaus N, Weber H, Adamski S, Murray EM, Zhang HZ, Zhao JZ, Ernst R, Lineberger J, Huang L, Hampton R, Arnold BA, Vitelli S, Hamuro L, Wang WR, Wei N, Dillon GM, Miao J, Alves SE, Glantschnig H, Wang F, Wilkinson HA.

J Gerontol A Biol Sci Med Sci. 2013 Oct;68(10):1181-92. doi: 10.1093/gerona/glt030. Epub 2013 Mar 22.

PMID:
23525481
16.

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.

Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM.

Nature. 2012 Jan 11;481(7382):463-8. doi: 10.1038/nature10777.

17.

Characterization of the ligand binding functionality of the extracellular domain of activin receptor type IIb.

Sako D, Grinberg AV, Liu J, Davies MV, Castonguay R, Maniatis S, Andreucci AJ, Pobre EG, Tomkinson KN, Monnell TE, Ucran JA, Martinez-Hackert E, Pearsall RS, Underwood KW, Seehra J, Kumar R.

J Biol Chem. 2010 Jul 2;285(27):21037-48. doi: 10.1074/jbc.M110.114959. Epub 2010 Apr 12.

18.

Targeting the activin type IIB receptor to improve muscle mass and function in the mdx mouse model of Duchenne muscular dystrophy.

Pistilli EE, Bogdanovich S, Goncalves MD, Ahima RS, Lachey J, Seehra J, Khurana T.

Am J Pathol. 2011 Mar;178(3):1287-97. doi: 10.1016/j.ajpath.2010.11.071.

19.

TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice.

Pan C, Singh S, Sahasrabudhe DM, Chakkalakal JV, Krolewski JJ, Nastiuk KL.

Endocrinology. 2016 Nov;157(11):4461-4472. Epub 2016 Sep 9.

PMID:
27611336
20.

Retinaldehyde dehydrogenase 1 regulates a thermogenic program in white adipose tissue.

Kiefer FW, Vernochet C, O'Brien P, Spoerl S, Brown JD, Nallamshetty S, Zeyda M, Stulnig TM, Cohen DE, Kahn CR, Plutzky J.

Nat Med. 2012 Jun;18(6):918-25. doi: 10.1038/nm.2757.

Supplemental Content

Support Center