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Items: 1 to 20 of 236

1.

Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice.

Pantelyushin S, Haak S, Ingold B, Kulig P, Heppner FL, Navarini AA, Becher B.

J Clin Invest. 2012 Jun;122(6):2252-6. doi: 10.1172/JCI61862. Epub 2012 May 1.

2.

IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice.

Van Belle AB, de Heusch M, Lemaire MM, Hendrickx E, Warnier G, Dunussi-Joannopoulos K, Fouser LA, Renauld JC, Dumoutier L.

J Immunol. 2012 Jan 1;188(1):462-9. doi: 10.4049/jimmunol.1102224. Epub 2011 Nov 30.

3.

IL-23 from Langerhans cells is required for the development of imiquimod-induced psoriasis-like dermatitis by induction of IL-17A-producing γδ T cells.

Yoshiki R, Kabashima K, Honda T, Nakamizo S, Sawada Y, Sugita K, Yoshioka H, Ohmori S, Malissen B, Tokura Y, Nakamura M.

J Invest Dermatol. 2014 Jul;134(7):1912-1921. doi: 10.1038/jid.2014.98. Epub 2014 Feb 25.

4.

Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.

Skepner J, Ramesh R, Trocha M, Schmidt D, Baloglu E, Lobera M, Carlson T, Hill J, Orband-Miller LA, Barnes A, Boudjelal M, Sundrud M, Ghosh S, Yang J.

J Immunol. 2014 Mar 15;192(6):2564-75. doi: 10.4049/jimmunol.1302190. Epub 2014 Feb 10.

5.

An alternative pathway of imiquimod-induced psoriasis-like skin inflammation in the absence of interleukin-17 receptor a signaling.

El Malki K, Karbach SH, Huppert J, Zayoud M, Reissig S, Schüler R, Nikolaev A, Karram K, Münzel T, Kuhlmann CR, Luhmann HJ, von Stebut E, Wörtge S, Kurschus FC, Waisman A.

J Invest Dermatol. 2013 Feb;133(2):441-51. doi: 10.1038/jid.2012.318. Epub 2012 Sep 6.

6.

TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses.

Massot B, Michel ML, Diem S, Ohnmacht C, Latour S, Dy M, Eberl G, Leite-de-Moraes MC.

J Immunol. 2014 Jun 15;192(12):5635-42. doi: 10.4049/jimmunol.1302089. Epub 2014 May 7.

7.

Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response.

Zákostelská Z, Málková J, Klimešová K, Rossmann P, Hornová M, Novosádová I, Stehlíková Z, Kostovčík M, Hudcovic T, Štepánková R, Jůzlová K, Hercogová J, Tlaskalová-Hogenová H, Kverka M.

PLoS One. 2016 Jul 19;11(7):e0159539. doi: 10.1371/journal.pone.0159539. eCollection 2016.

8.

Pivotal role of dermal IL-17-producing γδ T cells in skin inflammation.

Cai Y, Shen X, Ding C, Qi C, Li K, Li X, Jala VR, Zhang HG, Wang T, Zheng J, Yan J.

Immunity. 2011 Oct 28;35(4):596-610. doi: 10.1016/j.immuni.2011.08.001. Epub 2011 Oct 6. Erratum in: Immunity. 2011 Oct 28;35(4):649.

9.

Antrodia cinnamomea Extract Inhibits Th17 Cell Differentiation and Ameliorates Imiquimod-Induced Psoriasiform Skin Inflammation.

Li MH, Wu HC, Yao HJ, Lin CC, Wen SF, Pan IH.

Am J Chin Med. 2015;43(7):1401-17. doi: 10.1142/S0192415X15500792. Epub 2015 Oct 18.

PMID:
26477794
10.

Dermal γδ T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact Hypersensitivity.

Jiang X, Park CO, Geddes Sweeney J, Yoo MJ, Gaide O, Kupper TS.

PLoS One. 2017 Jan 12;12(1):e0169397. doi: 10.1371/journal.pone.0169397. eCollection 2017.

11.

Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin.

Smith SH, Peredo CE, Takeda Y, Bui T, Neil J, Rickard D, Millerman E, Therrien JP, Nicodeme E, Brusq JM, Birault V, Viviani F, Hofland H, Jetten AM, Cote-Sierra J.

PLoS One. 2016 Feb 12;11(2):e0147979. doi: 10.1371/journal.pone.0147979. eCollection 2016.

12.

IL-6 regulates neutrophil microabscess formation in IL-17A-driven psoriasiform lesions.

Croxford AL, Karbach S, Kurschus FC, Wörtge S, Nikolaev A, Yogev N, Klebow S, Schüler R, Reissig S, Piotrowski C, Brylla E, Bechmann I, Scheller J, Rose-John S, Thomas Wunderlich F, Münzel T, von Stebut E, Waisman A.

J Invest Dermatol. 2014 Mar;134(3):728-735. doi: 10.1038/jid.2013.404. Epub 2013 Sep 25.

13.

IL-27 activates Th1-mediated responses in imiquimod-induced psoriasis-like skin lesions.

Shibata S, Tada Y, Asano Y, Yanaba K, Sugaya M, Kadono T, Kanda N, Watanabe S, Sato S.

J Invest Dermatol. 2013 Feb;133(2):479-88. doi: 10.1038/jid.2012.313. Epub 2012 Sep 6.

14.

Cutting Edge: PD-1 Regulates Imiquimod-Induced Psoriasiform Dermatitis through Inhibition of IL-17A Expression by Innate γδ-Low T Cells.

Imai Y, Ayithan N, Wu X, Yuan Y, Wang L, Hwang ST.

J Immunol. 2015 Jul 15;195(2):421-5. doi: 10.4049/jimmunol.1500448. Epub 2015 Jun 5.

15.

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH.

Immunity. 2009 Aug 21;31(2):331-41. doi: 10.1016/j.immuni.2009.08.001. Epub 2009 Aug 13.

16.

Human mast cells are major IL-22 producers in patients with psoriasis and atopic dermatitis.

Mashiko S, Bouguermouh S, Rubio M, Baba N, Bissonnette R, Sarfati M.

J Allergy Clin Immunol. 2015 Aug;136(2):351-9.e1. doi: 10.1016/j.jaci.2015.01.033. Epub 2015 Mar 16.

PMID:
25792465
17.

In vivo induction of cutaneous inflammation results in the accumulation of extracellular trap-forming neutrophils expressing RORγt and IL-17.

Keijsers RRMC, Hendriks AGM, van Erp PEJ, van Cranenbroek B, van de Kerkhof PCM, Koenen HJPM, Joosten I.

J Invest Dermatol. 2014 May;134(5):1276-1284. doi: 10.1038/jid.2013.526. Epub 2013 Dec 6.

18.

Langerin(neg) conventional dendritic cells produce IL-23 to drive psoriatic plaque formation in mice.

Wohn C, Ober-Blöbaum JL, Haak S, Pantelyushin S, Cheong C, Zahner SP, Onderwater S, Kant M, Weighardt H, Holzmann B, Reizis B, Becher B, Prens EP, Clausen BE.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10723-8. doi: 10.1073/pnas.1307569110. Epub 2013 Jun 10.

19.

Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model.

Ueyama A, Imura C, Fusamae Y, Tsujii K, Furue Y, Aoki M, Suzuki M, Okuda T, Oshima I, Yasui K, Shichijo M, Yamamoto M.

J Dermatol Sci. 2017 Jan;85(1):27-35. doi: 10.1016/j.jdermsci.2016.10.007. Epub 2016 Oct 19.

PMID:
27810232
20.

Dermal IL-17-producing γδ T cells establish long-lived memory in the skin.

Hartwig T, Pantelyushin S, Croxford AL, Kulig P, Becher B.

Eur J Immunol. 2015 Nov;45(11):3022-33. doi: 10.1002/eji.201545883. Epub 2015 Oct 19.

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