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E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.

Sakamoto S, Wakae K, Anzai Y, Murai K, Tamaki N, Miyazaki M, Miyazaki K, Romanow WJ, Ikawa T, Kitamura D, Yanagihara I, Minato N, Murre C, Agata Y.

J Immunol. 2012 Jun 1;188(11):5547-60. doi: 10.4049/jimmunol.1002346. Epub 2012 Apr 27.


Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

Fitzsimmons SP, Bernstein RM, Max EE, Skok JA, Shapiro MA.

J Immunol. 2007 Oct 15;179(8):5264-73.


Regulation of TCR Vγ2 gene rearrangement by the helix-loop-helix protein, E2A.

Nozaki M, Wakae K, Tamaki N, Sakamoto S, Ohnishi K, Uejima T, Minato N, Yanagihara I, Agata Y.

Int Immunol. 2011 May;23(5):297-305. doi: 10.1093/intimm/dxr005. Epub 2011 Mar 18.


The Ig kappa 3' enhancer is activated by gradients of chromatin accessibility and protein association.

McDevit DC, Perkins L, Atchison ML, Nikolajczyk BS.

J Immunol. 2005 Mar 1;174(5):2834-42.


Chromatin remodeling at the Ig loci prior to V(D)J recombination.

Maës J, O'Neill LP, Cavelier P, Turner BM, Rougeon F, Goodhardt M.

J Immunol. 2001 Jul 15;167(2):866-74.


Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.

Langerak AW, Wolvers-Tettero IL, van Gastel-Mol EJ, Oud ME, van Dongen JJ.

Blood. 2001 Oct 15;98(8):2456-65.


Protein acetylation regulates both PU.1 transactivation and Ig kappa 3' enhancer activity.

Bai Y, Srinivasan L, Perkins L, Atchison ML.

J Immunol. 2005 Oct 15;175(8):5160-9.


Localized gene-specific induction of accessibility to V(D)J recombination induced by E2A and early B cell factor in nonlymphoid cells.

Goebel P, Janney N, Valenzuela JR, Romanow WJ, Murre C, Feeney AJ.

J Exp Med. 2001 Sep 3;194(5):645-56.


De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.

Manoharan A, Du Roure C, Rolink AG, Matthias P.

Eur J Immunol. 2015 Aug;45(8):2343-55. doi: 10.1002/eji.201445035. Epub 2015 Jun 16.


Transcription factor NF-kappa B regulates Ig lambda light chain gene rearrangement.

Bendall HH, Sikes ML, Oltz EM.

J Immunol. 2001 Jul 1;167(1):264-9.


Regulation of activation and recombination of the murine Igkappa locus.

Schlissel MS.

Immunol Rev. 2004 Aug;200:215-23. Review.


Pre-B cell receptor signaling induces immunoglobulin κ locus accessibility by functional redistribution of enhancer-mediated chromatin interactions.

Stadhouders R, de Bruijn MJ, Rother MB, Yuvaraj S, Ribeiro de Almeida C, Kolovos P, Van Zelm MC, van Ijcken W, Grosveld F, Soler E, Hendriks RW.

PLoS Biol. 2014 Feb 18;12(2):e1001791. doi: 10.1371/journal.pbio.1001791. eCollection 2014 Feb.


Dynamic Control of Long-Range Genomic Interactions at the Immunoglobulin κ Light-Chain Locus.

Ribeiro de Almeida C, Hendriks RW, Stadhouders R.

Adv Immunol. 2015;128:183-271. doi: 10.1016/ Epub 2015 Aug 14. Review.


Transcriptional activation of mouse TCR Jgamma4 germline promoter by STAT5.

Masui N, Tani-ichi S, Maki K, Ikuta K.

Mol Immunol. 2008 Feb;45(3):849-55. Epub 2007 Jul 30.


Chromatin structural analyses of the mouse Igkappa gene locus reveal new hypersensitive sites specifying a transcriptional silencer and enhancer.

Liu ZM, George-Raizen JB, Li S, Meyers KC, Chang MY, Garrard WT.

J Biol Chem. 2002 Sep 6;277(36):32640-9. Epub 2002 Jun 21.


E2A and EBF act in synergy with the V(D)J recombinase to generate a diverse immunoglobulin repertoire in nonlymphoid cells.

Romanow WJ, Langerak AW, Goebel P, Wolvers-Tettero IL, van Dongen JJ, Feeney AJ, Murre C.

Mol Cell. 2000 Feb;5(2):343-53.

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