Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 131

1.

Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).

Agrawal P, Chen YT, Schilling B, Gibson BW, Hughes RE.

J Biol Chem. 2012 Jun 15;287(25):21164-75. doi: 10.1074/jbc.M111.328021. Epub 2012 Apr 27.

2.

Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).

Ge Y, Yoon MS, Chen J.

J Biol Chem. 2011 Oct 14;286(41):35675-82. doi: 10.1074/jbc.M111.262881. Epub 2011 Aug 18.

3.

Ubiquitin hydrolase UCH-L1 destabilizes mTOR complex 1 by antagonizing DDB1-CUL4-mediated ubiquitination of raptor.

Hussain S, Feldman AL, Das C, Ziesmer SC, Ansell SM, Galardy PJ.

Mol Cell Biol. 2013 Mar;33(6):1188-97. doi: 10.1128/MCB.01389-12. Epub 2013 Jan 7.

4.

The mTORC2 complex regulates terminal differentiation of C2C12 myoblasts.

Shu L, Houghton PJ.

Mol Cell Biol. 2009 Sep;29(17):4691-700. doi: 10.1128/MCB.00764-09. Epub 2009 Jun 29.

5.

PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.

Woo SY, Kim DH, Jun CB, Kim YM, Haar EV, Lee SI, Hegg JW, Bandhakavi S, Griffin TJ, Kim DH.

J Biol Chem. 2007 Aug 31;282(35):25604-12. Epub 2007 Jun 28.

6.

TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.

Wang B, Jie Z, Joo D, Ordureau A, Liu P, Gan W, Guo J, Zhang J, North BJ, Dai X, Cheng X, Bian X, Zhang L, Harper JW, Sun SC, Wei W.

Nature. 2017 May 18;545(7654):365-369. doi: 10.1038/nature22344. Epub 2017 May 10.

PMID:
28489822
7.

The translation regulatory subunit eIF3f controls the kinase-dependent mTOR signaling required for muscle differentiation and hypertrophy in mouse.

Csibi A, Cornille K, Leibovitch MP, Poupon A, Tintignac LA, Sanchez AM, Leibovitch SA.

PLoS One. 2010 Feb 1;5(2):e8994. doi: 10.1371/journal.pone.0008994.

8.

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size.

Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ.

Am J Physiol Cell Physiol. 2009 Jun;296(6):C1258-70. doi: 10.1152/ajpcell.00105.2009. Epub 2009 Apr 8.

9.

mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.

Ekim B, Magnuson B, Acosta-Jaquez HA, Keller JA, Feener EP, Fingar DC.

Mol Cell Biol. 2011 Jul;31(14):2787-801. doi: 10.1128/MCB.05437-11. Epub 2011 May 16.

10.

mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.

Le Bacquer O, Queniat G, Gmyr V, Kerr-Conte J, Lefebvre B, Pattou F.

J Endocrinol. 2013 Jan 2;216(1):21-9. doi: 10.1530/JOE-12-0351. Print 2013 Jan.

11.
12.

Estrogen-related receptor α regulates skeletal myocyte differentiation via modulation of the ERK MAP kinase pathway.

Murray J, Huss JM.

Am J Physiol Cell Physiol. 2011 Sep;301(3):C630-45. doi: 10.1152/ajpcell.00033.2011. Epub 2011 May 11.

13.

Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1.

Huang S, Yang ZJ, Yu C, Sinicrope FA.

J Biol Chem. 2011 Nov 18;286(46):40002-12. doi: 10.1074/jbc.M111.297432. Epub 2011 Sep 23.

14.

Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.

Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M.

Int J Oncol. 2009 Oct;35(4):731-40.

PMID:
19724909
15.

RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.

Gordon BS, Kazi AA, Coleman CS, Dennis MD, Chau V, Jefferson LS, Kimball SR.

Cell Signal. 2014 Mar;26(3):461-7. doi: 10.1016/j.cellsig.2013.11.035. Epub 2013 Dec 3.

16.

Alcohol-induced modulation of rictor and mTORC2 activity in C2C12 myoblasts.

Hong-Brown LQ, Brown CR, Navaratnarajah M, Huber DS, Lang CH.

Alcohol Clin Exp Res. 2011 Aug;35(8):1445-53. doi: 10.1111/j.1530-0277.2011.01480.x. Epub 2011 Mar 25.

17.

mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.

Julien LA, Carriere A, Moreau J, Roux PP.

Mol Cell Biol. 2010 Feb;30(4):908-21. doi: 10.1128/MCB.00601-09. Epub 2009 Dec 7.

18.

mTOR phosphorylated at S2448 binds to raptor and rictor.

Rosner M, Siegel N, Valli A, Fuchs C, Hengstschläger M.

Amino Acids. 2010 Jan;38(1):223-8. doi: 10.1007/s00726-008-0230-7. Epub 2009 Jan 15.

PMID:
19145465
19.
20.

Distribution and association of mTOR with its cofactors, raptor and rictor, in cumulus cells and oocytes during meiotic maturation in mice.

Kogasaka Y, Hoshino Y, Hiradate Y, Tanemura K, Sato E.

Mol Reprod Dev. 2013 Apr;80(4):334-48. doi: 10.1002/mrd.22166. Epub 2013 Mar 26.

PMID:
23440873

Supplemental Content

Support Center